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Journal Abstract Search

132 related items for PubMed ID: 8099375

  • 1. Expression of dihydrofolate reductase and multidrug resistance genes in trimetrexate-resistant human leukemia cell lines.
    Li XK, Kobayashi H, Holland JF, Ohnuma T.
    Leuk Res; 1993 Jun; 17(6):483-90. PubMed ID: 8099375
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  • 3. Expression of variant dihydrofolate reductase with decreased binding affinity to antifolates in MOLT-3 human leukemia cell lines resistant to trimetrexate.
    Miyachi H, Takemura Y, Kobayashi H, Ando Y.
    Cancer Lett; 1995 Jan 06; 88(1):93-9. PubMed ID: 7850779
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  • 8. Cytotoxicity of trimetrexate against antifolate-resistant human T-cell leukemia cell lines developed in oxidized or reduced folate.
    Miyachi H, Takemura Y, Kobayashi H, Ando Y.
    Jpn J Cancer Res; 1997 Sep 06; 88(9):900-6. PubMed ID: 9369939
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  • 9. A phenotype conferring selective resistance to lipophilic antifolates in Chinese hamster ovary cells.
    Sharma RC, Assaraf YG, Schimke RT.
    Cancer Res; 1991 Jun 01; 51(11):2949-59. PubMed ID: 1674447
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  • 10. Differential reversal of lipophilic antifolate resistance in mammalian cells with modulators of the multidrug resistance phenotype.
    Assaraf YG, Borgnia MJ.
    Anticancer Drugs; 1993 Jun 01; 4(3):395-406. PubMed ID: 8102912
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  • 13. Protection of CCRF-CEM human lymphoid cells from antifolates by retroviral gene transfer of variants of murine dihydrofolate reductase.
    Mareya SM, Sorrentino BP, Blakley RL.
    Cancer Gene Ther; 1998 Jun 01; 5(4):225-35. PubMed ID: 9694074
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  • 14. Determinants of trimetrexate lethality in human colon cancer cells.
    Grem JL, Voeller DM, Geoffroy F, Horak E, Johnston PG, Allegra CJ.
    Br J Cancer; 1994 Dec 01; 70(6):1075-84. PubMed ID: 7981057
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  • 16. Identification of a distinctive P-glycoprotein-mediated resistance phenotype in human ovarian carcinoma cells after their in vitro exposure to fractionated X-irradiation.
    Hill BT, Whelan RD, Hurst HC, McClean S.
    Cancer; 1994 Jun 15; 73(12):2990-9. PubMed ID: 7911070
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  • 17. Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate.
    Diddens H, Niethammer D, Jackson RC.
    Cancer Res; 1983 Nov 15; 43(11):5286-92. PubMed ID: 6225514
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  • 18. Severe folate restriction results in depletion of and alteration in the composition of the intracellular folate pool, moderate sensitization to methotrexate and trimetrexate, upregulation of endogenous DHFR activity, and overexpression of metallothionein II and folate receptor alpha that, upon folate repletion, confer drug resistance to CHL cells.
    Zhu WY, Bunni M, Priest DG, DiCapua JL, Dressler JM, Chen Z, Melera PW.
    J Exp Ther Oncol; 2002 Nov 15; 2(5):264-77. PubMed ID: 12416030
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  • 20. Specificity of ribozyme designed for mutated DHFR mRNA.
    Kobayashi H, Kim N, Halatsch ME, Ohnuma T.
    Biochem Pharmacol; 1994 Apr 29; 47(9):1607-13. PubMed ID: 8185675
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