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Journal Abstract Search

570 related items for PubMed ID: 8103792

  • 1. RP 59037 and RP 60503: anxiolytic cyclopyrrolone derivatives with low sedative potential. interaction with the gamma-aminobutyric acidA/benzodiazepine receptor complex and behavioral effects in the rodent.
    Doble A, Canton T, Dreisler S, Piot O, Boireau A, Stutzmann JM, Bardone MC, Rataud J, Roux M, Roussel G.
    J Pharmacol Exp Ther; 1993 Sep; 266(3):1213-26. PubMed ID: 8103792
    [Abstract] [Full Text] [Related]

  • 2. The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors.
    Popik P, Kostakis E, Krawczyk M, Nowak G, Szewczyk B, Krieter P, Chen Z, Russek SJ, Gibbs TT, Farb DH, Skolnick P, Lippa AS, Basile AS.
    J Pharmacol Exp Ther; 2006 Dec; 319(3):1244-52. PubMed ID: 16971504
    [Abstract] [Full Text] [Related]

  • 3. CGS 20625, a novel pyrazolopyridine anxiolytic.
    Williams M, Bennett DA, Loo PS, Braunwalder AF, Amrick CL, Wilson DE, Thompson TN, Schmutz M, Yokoyoma N, Wasley JW.
    J Pharmacol Exp Ther; 1989 Jan; 248(1):89-96. PubMed ID: 2563294
    [Abstract] [Full Text] [Related]

  • 4. Zolpidem, a novel nonbenzodiazepine hypnotic. I. Neuropharmacological and behavioral effects.
    Depoortere H, Zivkovic B, Lloyd KG, Sanger DJ, Perrault G, Langer SZ, Bartholini G.
    J Pharmacol Exp Ther; 1986 May; 237(2):649-58. PubMed ID: 2871178
    [Abstract] [Full Text] [Related]

  • 5. 5-ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2a]pyridine-4-N-(2-fluorophenyl)carboxamide (RWJ-51204), a new nonbenzodiazepine anxiolytic.
    Dubinsky B, Vaidya AH, Rosenthal DI, Hochman C, Crooke JJ, DeLuca S, DeVine A, Cheo-Isaacs CT, Carter AR, Jordan AD, Reitz AB, Shank RP.
    J Pharmacol Exp Ther; 2002 Nov; 303(2):777-90. PubMed ID: 12388665
    [Abstract] [Full Text] [Related]

  • 6. SL651498: an anxioselective compound with functional selectivity for alpha2- and alpha3-containing gamma-aminobutyric acid(A) (GABA(A)) receptors.
    Griebel G, Perrault G, Simiand J, Cohen C, Granger P, Decobert M, Françon D, Avenet P, Depoortere H, Tan S, Oblin A, Schoemaker H, Evanno Y, Sevrin M, George P, Scatton B.
    J Pharmacol Exp Ther; 2001 Aug; 298(2):753-68. PubMed ID: 11454940
    [Abstract] [Full Text] [Related]

  • 7. The in vivo properties of pagoclone in rat are most likely mediated by 5'-hydroxy pagoclone.
    Atack JR, Pike A, Marshall G, Stanley J, Lincoln R, Cook SM, Lewis RT, Blackaby WP, Goodacre SC, McKernan RM, Dawson GR, Wafford KA, Reynolds DS.
    Neuropharmacology; 2006 May; 50(6):677-89. PubMed ID: 16430927
    [Abstract] [Full Text] [Related]

  • 8. Piperazine imidazo[1,5-a]quinoxaline ureas as high-affinity GABAA ligands of dual functionality.
    Jacobsen EJ, Stelzer LS, TenBrink RE, Belonga KL, Carter DB, Im HK, Im WB, Sethy VH, Tang AH, VonVoigtlander PF, Petke JD, Zhong WZ, Mickelson JW.
    J Med Chem; 1999 Apr 08; 42(7):1123-44. PubMed ID: 10197957
    [Abstract] [Full Text] [Related]

  • 9. Contribution of GABAA receptor subtypes to the anxiolytic-like, motor, and discriminative stimulus effects of benzodiazepines: studies with the functionally selective ligand SL651498 [6-fluoro-9-methyl-2-phenyl-4-(pyrrolidin-1-yl-carbonyl)-2,9-dihydro-1H-pyridol[3,4-b]indol-1-one].
    Licata SC, Platt DM, Cook JM, Sarma PV, Griebel G, Rowlett JK.
    J Pharmacol Exp Ther; 2005 Jun 08; 313(3):1118-25. PubMed ID: 15687371
    [Abstract] [Full Text] [Related]

  • 10. Relationship between benzodiazepine receptor occupancy and functional effects in vivo of four ligands of differing intrinsic efficacies.
    Facklam M, Schoch P, Bonetti EP, Jenck F, Martin JR, Moreau JL, Haefely WE.
    J Pharmacol Exp Ther; 1992 Jun 08; 261(3):1113-21. PubMed ID: 1318371
    [Abstract] [Full Text] [Related]

  • 11. Ethyl loflazepate: a prodrug from the benzodiazepine series designed to dissociate anxiolytic and sedative activities.
    Chambon JP, Perio A, Demarne H, Hallot A, Dantzer R, Roncucci R, Bizière K.
    Arzneimittelforschung; 1985 Jun 08; 35(10):1573-7. PubMed ID: 2866771
    [Abstract] [Full Text] [Related]

  • 12. CGS 9896: agonist-antagonist benzodiazepine receptor activity revealed by anxiolytic, anticonvulsant and muscle relaxation assessment in rodents.
    Bernard PS, Bennett DA, Pastor G, Yokoyama N, Liebman JM.
    J Pharmacol Exp Ther; 1985 Oct 08; 235(1):98-105. PubMed ID: 2995650
    [Abstract] [Full Text] [Related]

  • 13. Anticonvulsant, anxiolytic, and non-sedating actions of imidazenil and other imidazo-benzodiazepine carboxamide derivatives.
    Auta J, Kadriu B, Giusti P, Costa E, Guidotti A.
    Pharmacol Biochem Behav; 2010 Jun 08; 95(4):383-9. PubMed ID: 20227434
    [Abstract] [Full Text] [Related]

  • 14. Anxiolytic activity of a novel potent serotonin 5-HT2C receptor antagonist FR260010: a comparison with diazepam and buspirone.
    Harada K, Aota M, Inoue T, Matsuda R, Mihara T, Yamaji T, Ishibashi K, Matsuoka N.
    Eur J Pharmacol; 2006 Dec 28; 553(1-3):171-84. PubMed ID: 17074317
    [Abstract] [Full Text] [Related]

  • 15. A novel selective GABA(A) alpha1 receptor agonist displaying sedative and anxiolytic-like properties in rodents.
    Selleri S, Bruni F, Costagli C, Costanzo A, Guerrini G, Ciciani G, Gratteri P, Besnard F, Costa B, Montali M, Martini C, Fohlin J, De Siena G, Aiello PM.
    J Med Chem; 2005 Oct 20; 48(21):6756-60. PubMed ID: 16220991
    [Abstract] [Full Text] [Related]

  • 16. 3-Hydroxy-2'-methoxy-6-methylflavone: a potent anxiolytic with a unique selectivity profile at GABA(A) receptor subtypes.
    Karim N, Gavande N, Wellendorph P, Johnston GA, Hanrahan JR, Chebib M.
    Biochem Pharmacol; 2011 Dec 15; 82(12):1971-83. PubMed ID: 21924247
    [Abstract] [Full Text] [Related]

  • 17. Native gamma-aminobutyric acid type A receptors from rat hippocampus, containing both alpha 1 and alpha 5 subunits, exhibit a single benzodiazepine binding site with alpha 5 pharmacological properties.
    Araujo F, Ruano D, Vitorica J.
    J Pharmacol Exp Ther; 1999 Sep 15; 290(3):989-97. PubMed ID: 10454469
    [Abstract] [Full Text] [Related]

  • 18. Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.
    Rudolph U, Crestani F, Benke D, Brünig I, Benson JA, Fritschy JM, Martin JR, Bluethmann H, Möhler H.
    Nature; 1999 Oct 21; 401(6755):796-800. PubMed ID: 10548105
    [Abstract] [Full Text] [Related]

  • 19. Protracted treatment with diazepam reduces benzodiazepine1 receptor-mediated potentiation of gamma-aminobutyric acid-induced currents in dissociated rat hippocampal neurons.
    Itier V, Granger P, Perrault G, Depoortere H, Scatton B, Avenet P.
    J Pharmacol Exp Ther; 1996 Dec 21; 279(3):1092-9. PubMed ID: 8968329
    [Abstract] [Full Text] [Related]

  • 20. Pharmacological profile of the novel putative anxiolytic agent 1-amino-5-bromouracil.
    Imaizumi M, Miyazaki S, Watanabe Y, Machida H.
    Arzneimittelforschung; 1994 Mar 21; 44(3):285-8. PubMed ID: 7910744
    [Abstract] [Full Text] [Related]

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