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Journal Abstract Search

262 related items for PubMed ID: 8104125

  • 1. Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. II. Flavin-containing monooxygenase-mediated N-oxidation.
    Mani C, Hodgson E, Kupfer D.
    Drug Metab Dispos; 1993; 21(4):657-61. PubMed ID: 8104125
    [Abstract] [Full Text] [Related]

  • 2. Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation.
    Mani C, Gelboin HV, Park SS, Pearce R, Parkinson A, Kupfer D.
    Drug Metab Dispos; 1993; 21(4):645-56. PubMed ID: 8104124
    [Abstract] [Full Text] [Related]

  • 3. Cytochrome P-450-mediated activation and irreversible binding of the antiestrogen tamoxifen to proteins in rat and human liver: possible involvement of flavin-containing monooxygenases in tamoxifen activation.
    Mani C, Kupfer D.
    Cancer Res; 1991 Nov 15; 51(22):6052-8. PubMed ID: 1933868
    [Abstract] [Full Text] [Related]

  • 4. Oxidation of tamoxifen by human flavin-containing monooxygenase (FMO) 1 and FMO3 to tamoxifen-N-oxide and its novel reduction back to tamoxifen by human cytochromes P450 and hemoglobin.
    Parte P, Kupfer D.
    Drug Metab Dispos; 2005 Oct 15; 33(10):1446-52. PubMed ID: 15987777
    [Abstract] [Full Text] [Related]

  • 5. Flavin-containing monooxygenase-mediated N-oxidation of the M(1)-muscarinic agonist xanomeline.
    Ring BJ, Wrighton SA, Aldridge SL, Hansen K, Haehner B, Shipley LA.
    Drug Metab Dispos; 1999 Oct 15; 27(10):1099-103. PubMed ID: 10497134
    [Abstract] [Full Text] [Related]

  • 6. The aromatase inactivator 4-hydroxyandrostenedione (4-OH-A) inhibits tamoxifen metabolism by rat hepatic cytochrome P-450 3A: potential for drug-drug interaction of tamoxifen and 4-OH-A in combined anti-breast cancer therapy.
    Dehal SS, Brodie AM, Kupfer D.
    Drug Metab Dispos; 1999 Mar 15; 27(3):389-94. PubMed ID: 10064571
    [Abstract] [Full Text] [Related]

  • 7. Concurrent flavin-containing monooxygenase down-regulation and cytochrome P-450 induction by dietary indoles in rat: implications for drug-drug interaction.
    Katchamart S, Stresser DM, Dehal SS, Kupfer D, Williams DE.
    Drug Metab Dispos; 2000 Aug 15; 28(8):930-6. PubMed ID: 10901703
    [Abstract] [Full Text] [Related]

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  • 9. Methionine S-oxidation in human and rabbit liver microsomes: evidence for a high-affinity methionine S-oxidase activity that is distinct from flavin-containing monooxygenase 3.
    Ripp SL, Itagaki K, Philpot RM, Elfarra AA.
    Arch Biochem Biophys; 1999 Jul 15; 367(2):322-32. PubMed ID: 10395751
    [Abstract] [Full Text] [Related]

  • 10. Oxidation of caffeine to theobromine and theophylline is catalyzed primarily by flavin-containing monooxygenase in liver microsomes.
    Chung WG, Cha YN.
    Biochem Biophys Res Commun; 1997 Jun 27; 235(3):685-8. PubMed ID: 9207220
    [Abstract] [Full Text] [Related]

  • 11. The role of cytochromes P-450 and flavin-containing monooxygenase in the metabolism of (S)-nicotine by rabbit lung.
    Williams DE, Shigenaga MK, Castagnoli N.
    Drug Metab Dispos; 1990 Jun 27; 18(4):418-28. PubMed ID: 1976062
    [Abstract] [Full Text] [Related]

  • 12. CYP2D6 catalyzes tamoxifen 4-hydroxylation in human liver.
    Dehal SS, Kupfer D.
    Cancer Res; 1997 Aug 15; 57(16):3402-6. PubMed ID: 9270005
    [Abstract] [Full Text] [Related]

  • 13. Characterization and modulation by drugs of sheep liver microsomal flavin monooxygenase activity.
    Can Demirdöğen B, Adali O.
    Cell Biochem Funct; 2005 Aug 15; 23(4):245-51. PubMed ID: 15473006
    [Abstract] [Full Text] [Related]

  • 14. Roles of FMO and CYP450 in the metabolism in human liver microsomes of S-methyl-N,N-diethyldithiocarbamate, a disulfiram metabolite.
    Pike MG, Martin YN, Mays DC, Benson LM, Naylor S, Lipsky JJ.
    Alcohol Clin Exp Res; 1999 Jul 15; 23(7):1173-9. PubMed ID: 10443982
    [Abstract] [Full Text] [Related]

  • 15. An assay of flavin-containing monooxygenase activity with benzydamine N-oxidation.
    Kawaji A, Ohara K, Takabatake E.
    Anal Biochem; 1993 Nov 01; 214(2):409-12. PubMed ID: 8109727
    [Abstract] [Full Text] [Related]

  • 16. Loss of rat liver microsomal cytochrome P-450 during methimazole metabolism. Role of flavin-containing monooxygenase.
    Kedderis GL, Rickert DE.
    Drug Metab Dispos; 1985 Nov 01; 13(1):58-61. PubMed ID: 2858378
    [Abstract] [Full Text] [Related]

  • 17. Metabolism of ketoconazole and deacetylated ketoconazole by rat hepatic microsomes and flavin-containing monooxygenases.
    Rodriguez RJ, Acosta D.
    Drug Metab Dispos; 1997 Jun 01; 25(6):772-7. PubMed ID: 9193882
    [Abstract] [Full Text] [Related]

  • 18. Stereoselective N-oxygenation of zimeldine and homozimeldine by the flavin-containing monooxygenase.
    Cashman JR, Proudfoot J, Pate DW, Högberg T.
    Drug Metab Dispos; 1988 Jun 01; 16(4):616-22. PubMed ID: 2903032
    [Abstract] [Full Text] [Related]

  • 19. Liver microsome and flavin-containing monooxygenase catalyzed oxidation of organic selenium compounds.
    Chen GP, Ziegler DM.
    Arch Biochem Biophys; 1994 Aug 01; 312(2):566-72. PubMed ID: 8037472
    [Abstract] [Full Text] [Related]

  • 20. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug 01; (59):1-66, A1-E7. PubMed ID: 11803702
    [Abstract] [Full Text] [Related]

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