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Journal Abstract Search

262 related items for PubMed ID: 8104125

  • 1. Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. II. Flavin-containing monooxygenase-mediated N-oxidation.
    Mani C, Hodgson E, Kupfer D.
    Drug Metab Dispos; 1993; 21(4):657-61. PubMed ID: 8104125
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  • 2. Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation.
    Mani C, Gelboin HV, Park SS, Pearce R, Parkinson A, Kupfer D.
    Drug Metab Dispos; 1993; 21(4):645-56. PubMed ID: 8104124
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  • 3. Cytochrome P-450-mediated activation and irreversible binding of the antiestrogen tamoxifen to proteins in rat and human liver: possible involvement of flavin-containing monooxygenases in tamoxifen activation.
    Mani C, Kupfer D.
    Cancer Res; 1991 Nov 15; 51(22):6052-8. PubMed ID: 1933868
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  • 4. Oxidation of tamoxifen by human flavin-containing monooxygenase (FMO) 1 and FMO3 to tamoxifen-N-oxide and its novel reduction back to tamoxifen by human cytochromes P450 and hemoglobin.
    Parte P, Kupfer D.
    Drug Metab Dispos; 2005 Oct 15; 33(10):1446-52. PubMed ID: 15987777
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  • 5. Flavin-containing monooxygenase-mediated N-oxidation of the M(1)-muscarinic agonist xanomeline.
    Ring BJ, Wrighton SA, Aldridge SL, Hansen K, Haehner B, Shipley LA.
    Drug Metab Dispos; 1999 Oct 15; 27(10):1099-103. PubMed ID: 10497134
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  • 6. The aromatase inactivator 4-hydroxyandrostenedione (4-OH-A) inhibits tamoxifen metabolism by rat hepatic cytochrome P-450 3A: potential for drug-drug interaction of tamoxifen and 4-OH-A in combined anti-breast cancer therapy.
    Dehal SS, Brodie AM, Kupfer D.
    Drug Metab Dispos; 1999 Mar 15; 27(3):389-94. PubMed ID: 10064571
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  • 7. Concurrent flavin-containing monooxygenase down-regulation and cytochrome P-450 induction by dietary indoles in rat: implications for drug-drug interaction.
    Katchamart S, Stresser DM, Dehal SS, Kupfer D, Williams DE.
    Drug Metab Dispos; 2000 Aug 15; 28(8):930-6. PubMed ID: 10901703
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  • 9. Methionine S-oxidation in human and rabbit liver microsomes: evidence for a high-affinity methionine S-oxidase activity that is distinct from flavin-containing monooxygenase 3.
    Ripp SL, Itagaki K, Philpot RM, Elfarra AA.
    Arch Biochem Biophys; 1999 Jul 15; 367(2):322-32. PubMed ID: 10395751
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  • 12. CYP2D6 catalyzes tamoxifen 4-hydroxylation in human liver.
    Dehal SS, Kupfer D.
    Cancer Res; 1997 Aug 15; 57(16):3402-6. PubMed ID: 9270005
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  • 17. Metabolism of ketoconazole and deacetylated ketoconazole by rat hepatic microsomes and flavin-containing monooxygenases.
    Rodriguez RJ, Acosta D.
    Drug Metab Dispos; 1997 Jun 15; 25(6):772-7. PubMed ID: 9193882
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  • 18. Stereoselective N-oxygenation of zimeldine and homozimeldine by the flavin-containing monooxygenase.
    Cashman JR, Proudfoot J, Pate DW, Högberg T.
    Drug Metab Dispos; 1988 Jun 15; 16(4):616-22. PubMed ID: 2903032
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  • 19. Liver microsome and flavin-containing monooxygenase catalyzed oxidation of organic selenium compounds.
    Chen GP, Ziegler DM.
    Arch Biochem Biophys; 1994 Aug 01; 312(2):566-72. PubMed ID: 8037472
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  • 20. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug 01; (59):1-66, A1-E7. PubMed ID: 11803702
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