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111 related items for PubMed ID: 8129749

  • 1. Liarozole fumarate inhibits the metabolism of 4-keto-all-trans-retinoic acid.
    Van Wauwe J, Coene MC, Cools W, Goossens J, Lauwers W, Le Jeune L, Van Hove C, Van Nyen G.
    Biochem Pharmacol; 1994 Feb 11; 47(4):737-41. PubMed ID: 8129749
    [Abstract] [Full Text] [Related]

  • 2. Liarozole, an inhibitor of retinoic acid metabolism, exerts retinoid-mimetic effects in vivo.
    Van Wauwe J, Van Nyen G, Coene MC, Stoppie P, Cools W, Goossens J, Borghgraef P, Janssen PA.
    J Pharmacol Exp Ther; 1992 May 11; 261(2):773-9. PubMed ID: 1374473
    [Abstract] [Full Text] [Related]

  • 3. The antiproliferative activity of all-trans-retinoic acid catabolites and isomers is differentially modulated by liarozole-fumarate in MCF-7 human breast cancer cells.
    Van heusden J, Wouters W, Ramaekers FC, Krekels MD, Dillen L, Borgers M, Smets G.
    Br J Cancer; 1998 Apr 11; 77(8):1229-35. PubMed ID: 9579827
    [Abstract] [Full Text] [Related]

  • 4. Effects of liarozole, a new antitumoral compound, on retinoic acid-induced inhibition of cell growth and on retinoic acid metabolism in MCF-7 human breast cancer cells.
    Wouters W, van Dun J, Dillen A, Coene MC, Cools W, De Coster R.
    Cancer Res; 1992 May 15; 52(10):2841-6. PubMed ID: 1581897
    [Abstract] [Full Text] [Related]

  • 5. Ketoconazole inhibits the in vitro and in vivo metabolism of all-trans-retinoic acid.
    Van Wauwe JP, Coene MC, Goossens J, Van Nijen G, Cools W, Lauwers W.
    J Pharmacol Exp Ther; 1988 May 15; 245(2):718-22. PubMed ID: 3367313
    [Abstract] [Full Text] [Related]

  • 6. Modulation of all-trans retinoic acid pharmacokinetics by liarozole.
    Miller VA, Rigas JR, Muindi JR, Tong WP, Venkatraman E, Kris MG, Warrell RP.
    Cancer Chemother Pharmacol; 1994 May 15; 34(6):522-6. PubMed ID: 7923564
    [Abstract] [Full Text] [Related]

  • 7. Cytochrome-P-450-dependent metabolism of retinoic acid in rat skin microsomes: inhibition by ketoconazole.
    Vanden Bossche H, Willemsens G, Janssen PA.
    Skin Pharmacol; 1988 May 15; 1(3):176-85. PubMed ID: 2856164
    [Abstract] [Full Text] [Related]

  • 8. Liarozole inhibits human epidermal retinoic acid 4-hydroxylase activity and differentially augments human skin responses to retinoic acid and retinol in vivo.
    Kang S, Duell EA, Kim KJ, Voorhees JJ.
    J Invest Dermatol; 1996 Aug 15; 107(2):183-7. PubMed ID: 8757760
    [Abstract] [Full Text] [Related]

  • 9. Induction of the oxidative catabolism of retinoid acid in MCF-7 cells.
    Krekels MD, Verhoeven A, van Dun J, Cools W, Van Hove C, Dillen L, Coene MC, Wouters W.
    Br J Cancer; 1997 Aug 15; 75(8):1098-104. PubMed ID: 9099955
    [Abstract] [Full Text] [Related]

  • 10. Metabolism of all-trans-retinoic acid in hamster liver microsomes: oxidation of 4-hydroxy- to 4-keto-retinoic acid.
    Roberts AB, Lamb LC, Sporn MB.
    Arch Biochem Biophys; 1980 Feb 15; 199(2):374-83. PubMed ID: 7362233
    [No Abstract] [Full Text] [Related]

  • 11. Metabolism of vitamin A and its active metabolite all-trans-retinoic acid in small intestinal enterocytes.
    Lampen A, Meyer S, Arnhold T, Nau H.
    J Pharmacol Exp Ther; 2000 Dec 15; 295(3):979-85. PubMed ID: 11082432
    [Abstract] [Full Text] [Related]

  • 12. Both all-trans retinoic acid and cytochrome P450 (CYP26) inhibitors affect the expression of vitamin A metabolizing enzymes and retinoid biomarkers in organotypic epidermis.
    Pavez Loriè E, Chamcheu JC, Vahlquist A, Törmä H.
    Arch Dermatol Res; 2009 Aug 15; 301(7):475-85. PubMed ID: 19294396
    [Abstract] [Full Text] [Related]

  • 13. Recent advances in the in vivo and in vitro metabolism of retinoic acid.
    Roberts AB, Frolik CA.
    Fed Proc; 1979 Oct 15; 38(11):2524-7. PubMed ID: 488375
    [Abstract] [Full Text] [Related]

  • 14. Ethanol enhances retinoic acid metabolism into polar metabolites in rat liver via induction of cytochrome P4502E1.
    Liu C, Russell RM, Seitz HK, Wang XD.
    Gastroenterology; 2001 Jan 15; 120(1):179-89. PubMed ID: 11208727
    [Abstract] [Full Text] [Related]

  • 15. Analysis of the oxidative catabolism of retinoic acid in rat Dunning R3327G prostate tumors.
    Krekels MD, Zimmerman J, Janssens B, Van Ginckel R, Cools W, Van Hove C, Coene MC, Wouters W.
    Prostate; 1996 Jul 15; 29(1):36-41. PubMed ID: 8685053
    [Abstract] [Full Text] [Related]

  • 16. Liarozole markedly increases all trans-retinoic acid toxicity in mouse limb bud cell cultures: a model to explain the potency of the aromatic retinoid (E)-4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylenyl)-1-propenyl] benzoic acid.
    Pignatello MA, Kauffman FC, Levin AA.
    Toxicol Appl Pharmacol; 2002 Feb 01; 178(3):186-94. PubMed ID: 11858735
    [Abstract] [Full Text] [Related]

  • 17. Experimental studies with liarozole (R 75,251): an antitumoral agent which inhibits retinoic acid breakdown.
    De Coster R, Wouters W, Van Ginckel R, End D, Krekels M, Coene MC, Bowden C.
    J Steroid Biochem Mol Biol; 1992 Sep 01; 43(1-3):197-201. PubMed ID: 1525060
    [Abstract] [Full Text] [Related]

  • 18. Liarozole potentiates the cancer chemopreventive activity of and the up-regulation of gap junctional communication and connexin43 expression by retinoic acid and beta-carotene in 10T1/2 cells.
    Acevedo P, Bertram JS.
    Carcinogenesis; 1995 Sep 01; 16(9):2215-22. PubMed ID: 7554078
    [Abstract] [Full Text] [Related]

  • 19. Glucuronidation and isomerization of all-trans- and 13-cis-retinoic acid by liver microsomes of phenobarbital- or 3-methylcholanthrene-treated rats.
    Sass JO, Forster A, Bock KW, Nau H.
    Biochem Pharmacol; 1994 Feb 09; 47(3):485-92. PubMed ID: 8117316
    [Abstract] [Full Text] [Related]

  • 20. Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.
    Marill J, Cresteil T, Lanotte M, Chabot GG.
    Mol Pharmacol; 2000 Dec 09; 58(6):1341-8. PubMed ID: 11093772
    [Abstract] [Full Text] [Related]

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