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Journal Abstract Search

113 related items for PubMed ID: 8135801

  • 1. Point mutations of the thyrotropin receptor determining structural requirements for its ability to bind thyrotropin and to stimulate adenylate cyclase activity.
    Gustavsson B, Westermark B, Heldin NE.
    Biochem Biophys Res Commun; 1994 Mar 15; 199(2):612-8. PubMed ID: 8135801
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  • 2. The intracellular region adjacent to plasma membrane (residues 684-692) of the thyrotropin receptor is important for phosphoinositide signaling but not for agonist-induced adenylate cyclase activation.
    Kosugi S, Mori T.
    Biochem Biophys Res Commun; 1994 Mar 30; 199(3):1497-503. PubMed ID: 8147896
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  • 3. Role of cysteine residues in the extracellular domain and exoplasmic loops of the transmembrane domain of the TSH receptor: effect of mutation to serine on TSH receptor activity and response to thyroid stimulating autoantibodies.
    Kosugi S, Ban T, Akamizu T, Kohn LD.
    Biochem Biophys Res Commun; 1992 Dec 30; 189(3):1754-62. PubMed ID: 1336379
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  • 4. Germline mutations in the thyrotropin receptor gene cause non-autoimmune autosomal dominant hyperthyroidism.
    Duprez L, Parma J, Van Sande J, Allgeier A, Leclère J, Schvartz C, Delisle MJ, Decoulx M, Orgiazzi J, Dumont J.
    Nat Genet; 1994 Jul 30; 7(3):396-401. PubMed ID: 7920658
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  • 5. Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas.
    Parma J, Duprez L, Van Sande J, Cochaux P, Gervy C, Mockel J, Dumont J, Vassart G.
    Nature; 1993 Oct 14; 365(6447):649-51. PubMed ID: 8413627
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  • 9. Mutations of thyrotropin receptor isolated from thyroid autonomous functioning adenomas confer TSH-independent growth to thyroid cells.
    Porcellini A, Ruggiano G, Pannain S, Ciullo I, Amabile G, Fenzi G, Avvedimento EV.
    Oncogene; 1997 Aug 14; 15(7):781-9. PubMed ID: 9266964
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  • 10. Identification of TSH receptor mutations in three families with resistance to TSH.
    Tonacchera M, Di Cosmo C, De Marco G, Agretti P, Banco M, Perri A, Gianetti E, Montanelli L, Vitti P, Pinchera A.
    Clin Endocrinol (Oxf); 2007 Nov 14; 67(5):712-8. PubMed ID: 17697008
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  • 12. Further studies of amino acids (268-304) in thyrotropin (TSH)--lutropin/chorionic gonadotropin (LH/CG) receptor chimeras: cysteine-301 is important in TSH binding and receptor tertiary structure.
    Akamizu T, Inoue D, Kosugi S, Kohn LD, Mori T.
    Thyroid; 1994 Nov 14; 4(1):43-8. PubMed ID: 8054860
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  • 14. Further characterization of a high affinity thyrotropin binding site on the rat thyrotropin receptor which is an epitope for blocking antibodies from idiopathic myxedema patients but not thyroid stimulating antibodies from Graves' patients.
    Kosugi S, Ban T, Akamizu T, Kohn LD.
    Biochem Biophys Res Commun; 1991 Oct 31; 180(2):1118-24. PubMed ID: 1719963
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  • 16. Constitutive activation of the thyrotropin receptor by mutating CYS-636 in the sixth transmembrane segment.
    Kosugi S, Mori T.
    Biochem Biophys Res Commun; 1996 May 24; 222(3):713-7. PubMed ID: 8651910
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  • 18. Functional significance of cysteine residues in the delta opioid receptor studied by site-directed mutagenesis.
    Ehrlich GK, Andria ML, Zheng X, Kieffer B, Gioannini TL, Hiller JM, Rosenkranz JE, Veksler BM, Zukin RS, Simon EJ.
    Can J Physiol Pharmacol; 1998 Mar 24; 76(3):269-77. PubMed ID: 9673790
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  • 19. Expression of the human TSH receptor in a human thyroid carcinoma cell line that lacks an endogenous TSH receptor: growth inhibition by cAMP.
    Derwahl M, Kuemmel M, Goretzki P, Schatz H, Broecker M.
    Biochem Biophys Res Commun; 1993 Mar 31; 191(3):1131-8. PubMed ID: 8385451
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  • 20. Cysteine residues are involved in structure and function of melanocortin 1 receptor: Substitution of a cysteine residue in transmembrane segment two converts an agonist to antagonist.
    Frändberg PA, Doufexis M, Kapas S, Chhajlani V.
    Biochem Biophys Res Commun; 2001 Mar 09; 281(4):851-7. PubMed ID: 11237737
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