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Journal Abstract Search

198 related items for PubMed ID: 8142400

  • 1. Mapping of the thrombin des-ETW conformation by using site-directed mutants of hirudin. Evidence for the induction of nonlocal modifications by mutagenesis.
    Le Bonniec BF, Betz A, Guinto ER, Esmon CT, Stone SR.
    Biochemistry; 1994 Apr 05; 33(13):3959-66. PubMed ID: 8142400
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  • 2. Interaction of thrombin des-ETW with antithrombin III, the Kunitz inhibitors, thrombomodulin and protein C. Structural link between the autolysis loop and the Tyr-Pro-Pro-Trp insertion of thrombin.
    Le Bonniec BF, Guinto ER, Esmon CT.
    J Biol Chem; 1992 Sep 25; 267(27):19341-8. PubMed ID: 1326550
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  • 3. Interaction of the N-terminal region of hirudin with the active-site cleft of thrombin.
    Betz A, Hofsteenge J, Stone SR.
    Biochemistry; 1992 May 19; 31(19):4557-62. PubMed ID: 1581311
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  • 4. Electrostatic steering and ionic tethering in the formation of thrombin-hirudin complexes: the role of the thrombin anion-binding exosite-I.
    Myles T, Le Bonniec BF, Betz A, Stone SR.
    Biochemistry; 2001 Apr 24; 40(16):4972-9. PubMed ID: 11305913
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  • 5. Contribution of interactions with the core domain of hirudin to the stability of its complex with thrombin.
    Betz A, Hopkins PC, Le Bonniec BF, Stone SR.
    Biochem J; 1994 Mar 01; 298 ( Pt 2)(Pt 2):507-10. PubMed ID: 8135762
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  • 6. Heparin enhances the catalytic activity of des-ETW-thrombin.
    Goodwin CA, Deadman JJ, Le Bonniec BF, Elgendy S, Kakkar VV, Scully MF.
    Biochem J; 1996 Apr 01; 315 ( Pt 1)(Pt 1):77-83. PubMed ID: 8670135
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  • 7. Role of interactions involving C-terminal nonpolar residues of hirudin in the formation of the thrombin-hirudin complex.
    Betz A, Hofsteenge J, Stone SR.
    Biochemistry; 1991 Oct 15; 30(41):9848-53. PubMed ID: 1911777
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  • 9. Thermodynamic investigation of hirudin binding to the slow and fast forms of thrombin: evidence for folding transitions in the inhibitor and protease coupled to binding.
    Ayala YM, Vindigni A, Nayal M, Spolar RS, Record MT, Di Cera E.
    J Mol Biol; 1995 Nov 10; 253(5):787-98. PubMed ID: 7473752
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  • 12. Interactions of hirudin-based inhibitor with thrombin: critical role of the IleH59 side chain of the inhibitor.
    Tsuda Y, Szewczuk Z, Wang J, Yue SY, Purisima E, Konishi Y.
    Biochemistry; 1995 Jul 11; 34(27):8708-14. PubMed ID: 7612610
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  • 15. Molecular recognition by thrombin. Role of the slow-->fast transition, site-specific ion binding energetics and thermodynamic mapping of structural components.
    Ayala Y, Di Cera E.
    J Mol Biol; 1994 Jan 14; 235(2):733-46. PubMed ID: 8289292
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  • 16. Identification of regions of alpha-thrombin involved in its interaction with hirudin.
    Stone SR, Braun PJ, Hofsteenge J.
    Biochemistry; 1987 Jul 28; 26(15):4617-24. PubMed ID: 3663613
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  • 17. Identification of thrombin residues that modulate its interactions with antithrombin III and alpha 1-antitrypsin.
    Le Bonniec BF, Guinto ER, Stone SR.
    Biochemistry; 1995 Sep 26; 34(38):12241-8. PubMed ID: 7547966
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