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Journal Abstract Search

293 related items for PubMed ID: 8149894

  • 1. In vitro biotransformation of finasteride in rat hepatic microsomes. Isolation and characterization of metabolites.
    Ishii Y, Mukoyama H, Ohtawa M.
    Drug Metab Dispos; 1994; 22(1):79-84. PubMed ID: 8149894
    [Abstract] [Full Text] [Related]

  • 2. Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride.
    Huskey SW, Dean DC, Miller RR, Rasmusson GH, Chiu SH.
    Drug Metab Dispos; 1995 Oct; 23(10):1126-35. PubMed ID: 8654202
    [Abstract] [Full Text] [Related]

  • 3. Metabolism of the proestrogenic pesticide methoxychlor by hepatic P450 monooxygenases in rats and humans. Dual pathways involving novel ortho ring-hydroxylation by CYP2B.
    Dehal SS, Kupfer D.
    Drug Metab Dispos; 1994 Oct; 22(6):937-46. PubMed ID: 7895613
    [Abstract] [Full Text] [Related]

  • 4. Metabolism of finasteride in rat hepatic microsomes: age and sex differences and effects of P450 inducers.
    Ishii Y, Mukoyama H, Hata S.
    Xenobiotica; 1994 Sep; 24(9):863-72. PubMed ID: 7810168
    [Abstract] [Full Text] [Related]

  • 5. Metabolism of 2-amino-alpha-carboline. A food-borne heterocyclic amine mutagen and carcinogen by human and rodent liver microsomes and by human cytochrome P4501A2.
    Raza H, King RS, Squires RB, Guengerich FP, Miller DW, Freeman JP, Lang NP, Kadlubar FF.
    Drug Metab Dispos; 1996 Apr; 24(4):395-400. PubMed ID: 8801053
    [Abstract] [Full Text] [Related]

  • 6. Biotransformation of lovastatin. II. In vitro metabolism by rat and mouse liver microsomes and involvement of cytochrome P-450 in dehydrogenation of lovastatin.
    Vyas KP, Kari PH, Prakash SR, Duggan DE.
    Drug Metab Dispos; 1990 Apr; 18(2):218-22. PubMed ID: 1971576
    [Abstract] [Full Text] [Related]

  • 7. 3-ketocholanoic acid is the major in vitro human hepatic microsomal metabolite of lithocholic acid.
    Deo AK, Bandiera SM.
    Drug Metab Dispos; 2009 Sep; 37(9):1938-47. PubMed ID: 19487251
    [Abstract] [Full Text] [Related]

  • 8. Characterization of verlukast metabolites arising from an epoxide intermediate produced with hepatic microsomes from beta-naphthoflavone-treated rodents (P-4501A1).
    Nicoll-Griffith DA, Chauret N, Yergey JA, Trimble LA, Favreau L, Zamboni R, Grossman SJ, Drey J, Herold E.
    Drug Metab Dispos; 1993 Sep; 21(5):861-7. PubMed ID: 7902249
    [Abstract] [Full Text] [Related]

  • 9. Metabolism of a nitrogen-containing steroid by rat hepatocytes and hepatic subcellular fractions.
    Kedderis GL, Argenbright LS, Walsh JS, Smith JL, Stearns RA, Arison BA, Miwa GT.
    Drug Metab Dispos; 1989 Sep; 17(6):606-11. PubMed ID: 2575495
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  • 12. In vitro metabolism of L-696,229, an HIV-1 reverse transcriptase inhibitor in rats and humans. Hepatic and extrahepatic metabolism and identification of enzymes involved in the hepatic metabolism.
    Prueksaritanont T, Dwyer LM, Balani SK, Theoharides AD.
    Drug Metab Dispos; 1994 Sep; 22(2):281-8. PubMed ID: 7516854
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  • 14. In vitro metabolism of the antianxiety drug buspirone as a predictor of its metabolism in vivo.
    Jajoo HK, Blair IA, Klunk LJ, Mayol RF.
    Xenobiotica; 1990 Aug; 20(8):779-86. PubMed ID: 2219961
    [Abstract] [Full Text] [Related]

  • 15. Metabolism of the cytochrome P450 mechanism-based inhibitor N-benzyl-1-aminobenzotriazole to products that covalently bind with protein in guinea pig liver and lung microsomes: comparative study with 1-aminobenzotriazole.
    Woodcroft KJ, Webb CD, Yao M, Weedon AC, Bend JR.
    Chem Res Toxicol; 1997 May; 10(5):589-99. PubMed ID: 9168258
    [Abstract] [Full Text] [Related]

  • 16. Enzymatic C-demethylation of 1-[2-(5-tert-butyl-[1,3,4] oxadiazole-2-carbonyl)-4-fluoro-pyrrolidin-1-yl]-2-(2-hydroxy-1,1-dimethyl-ethylamino)-ethanone (LC15-0133) in rat liver microsomes.
    Yoo HH, Chung HJ, Lee J, Lee CS, Kang MJ, Kim DH.
    Drug Metab Dispos; 2008 Mar; 36(3):485-9. PubMed ID: 18057116
    [Abstract] [Full Text] [Related]

  • 17. In vitro hydroxylation and epoxidation of some isomeric lauric acid analogs by rat liver microsomes. Identification of metabolites and effects of clofibrate or phenobarbital pretreatment.
    Boucher JL, Delaforge M, Salaün JP, Pinot F, Durst F, Pflieger P, Mioskowski C.
    Drug Metab Dispos; 1996 Apr; 24(4):462-8. PubMed ID: 8801062
    [Abstract] [Full Text] [Related]

  • 18. In vitro metabolism of ethoxidine by human CYP1A1 and rat microsomes: identification of metabolites by high-performance liquid chromatography combined with electrospray tandem mass spectrometry and accurate mass measurements by time-of-flight mass spectrometry.
    Deroussent A, Ré M, Hoellinger H, Vanquelef E, Duval O, Sonnier M, Cresteil T.
    Rapid Commun Mass Spectrom; 2004 Apr; 18(4):474-82. PubMed ID: 14966856
    [Abstract] [Full Text] [Related]

  • 19. In vitro biotransformation of 3,4-dihydro-6-hydroxy-2,2-dimethyl-7-methoxy-1(2H)-benzopyran (CR-6), a potent lipid peroxidation inhibitor and nitric oxide scavenger, in rat liver microsomes.
    Yenes S, Commandeur JN, Vermeulen NP, Messeguer A.
    Chem Res Toxicol; 2004 Jul; 17(7):904-13. PubMed ID: 15257615
    [Abstract] [Full Text] [Related]

  • 20. Enhanced inhibition of microsomal cytochrome P450 3A2 in rat liver during diltiazem biotransformation.
    Murray M, Butler AM.
    J Pharmacol Exp Ther; 1996 Dec; 279(3):1447-52. PubMed ID: 8968370
    [Abstract] [Full Text] [Related]

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