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293 related items for PubMed ID: 8152525

  • 1. Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5-dimethyladamantan).
    Parsons CG, Gruner R, Rozental J, Millar J, Lodge D.
    Neuropharmacology; 1993 Dec; 32(12):1337-50. PubMed ID: 8152525
    [Abstract] [Full Text] [Related]

  • 2. Comparative patch-clamp studies with freshly dissociated rat hippocampal and striatal neurons on the NMDA receptor antagonistic effects of amantadine and memantine.
    Parsons CG, Panchenko VA, Pinchenko VO, Tsyndrenko AY, Krishtal OA.
    Eur J Neurosci; 1996 Mar; 8(3):446-54. PubMed ID: 8963435
    [Abstract] [Full Text] [Related]

  • 3. Comparison of the potency, kinetics and voltage-dependency of a series of uncompetitive NMDA receptor antagonists in vitro with anticonvulsive and motor impairment activity in vivo.
    Parsons CG, Quack G, Bresink I, Baran L, Przegalinski E, Kostowski W, Krzascik P, Hartmann S, Danysz W.
    Neuropharmacology; 1995 Oct; 34(10):1239-58. PubMed ID: 8570022
    [Abstract] [Full Text] [Related]

  • 4. Effects of memantine and MK-801 on NMDA-induced currents in cultured neurones and on synaptic transmission and LTP in area CA1 of rat hippocampal slices.
    Frankiewicz T, Potier B, Bashir ZI, Collingridge GL, Parsons CG.
    Br J Pharmacol; 1996 Feb; 117(4):689-97. PubMed ID: 8646415
    [Abstract] [Full Text] [Related]

  • 5. Budipine is a low affinity, N-methyl-D-aspartate receptor antagonist: patch clamp studies in cultured striatal, hippocampal, cortical and superior colliculus neurones.
    Parsons CG, Hartmann S, Spielmanns P.
    Neuropharmacology; 1998 Jun; 37(6):719-27. PubMed ID: 9707285
    [Abstract] [Full Text] [Related]

  • 6. Agonist concentration dependency of blocking kinetics but not equilibrium block of N-methyl-D-aspartate receptors by memantine.
    Gilling KE, Jatzke C, Parsons CG.
    Neuropharmacology; 2007 Sep; 53(3):415-20. PubMed ID: 17632186
    [Abstract] [Full Text] [Related]

  • 7. Potency, voltage-dependency, agonist concentration-dependency, blocking kinetics and partial untrapping of the uncompetitive N-methyl-D-aspartate (NMDA) channel blocker memantine at human NMDA (GluN1/GluN2A) receptors.
    Gilling KE, Jatzke C, Hechenberger M, Parsons CG.
    Neuropharmacology; 2009 Apr; 56(5):866-75. PubMed ID: 19371579
    [Abstract] [Full Text] [Related]

  • 8. Effects of memantine on recombinant rat NMDA receptors expressed in HEK 293 cells.
    Bresink I, Benke TA, Collett VJ, Seal AJ, Parsons CG, Henley JM, Collingridge GL.
    Br J Pharmacol; 1996 Sep; 119(2):195-204. PubMed ID: 8886398
    [Abstract] [Full Text] [Related]

  • 9. Comparative patch clamp studies on the kinetics and selectivity of glutamate receptor antagonism by 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) and 1-(4-amino-phenyl)-4-methyl-7,8-methyl-endioxyl-5H-2,3-benzodiaze pine (GYKI 52466).
    Parsons CG, Gruner R, Rozental J.
    Neuropharmacology; 1994 May; 33(5):589-604. PubMed ID: 7523977
    [Abstract] [Full Text] [Related]

  • 10. Arcaine blocks N-methyl-D-aspartate receptor responses by an open channel mechanism: whole-cell and single-channel recording studies in cultured hippocampal neurons.
    Donevan SD, Jones SM, Rogawski MA.
    Mol Pharmacol; 1992 Apr; 41(4):727-35. PubMed ID: 1373801
    [Abstract] [Full Text] [Related]

  • 11. Block of the N-methyl-D-aspartate receptor by remacemide and its des-glycine metabolite.
    Subramaniam S, Donevan SD, Rogawski MA.
    J Pharmacol Exp Ther; 1996 Jan; 276(1):161-8. PubMed ID: 8558426
    [Abstract] [Full Text] [Related]

  • 12. Effects of the N-methyl-D-aspartate antagonists on the rise in [Ca2+]i following depolarization in aged rat brain synaptosomes.
    Okada M, Urae A, Iwasaki K, Mine K, Fujiwara M.
    Brain Res; 1992 Jun 26; 583(1-2):227-36. PubMed ID: 1387038
    [Abstract] [Full Text] [Related]

  • 13. Recovery of NMDA receptor currents from MK-801 blockade is accelerated by Mg2+ and memantine under conditions of agonist exposure.
    McKay S, Bengtson CP, Bading H, Wyllie DJ, Hardingham GE.
    Neuropharmacology; 2013 Nov 26; 74():119-25. PubMed ID: 23402996
    [Abstract] [Full Text] [Related]

  • 14. Kynurenic acid analogues with improved affinity and selectivity for the glycine site on the N-methyl-D-aspartate receptor from rat brain.
    Foster AC, Kemp JA, Leeson PD, Grimwood S, Donald AE, Marshall GR, Priestley T, Smith JD, Carling RW.
    Mol Pharmacol; 1992 May 26; 41(5):914-22. PubMed ID: 1375317
    [Abstract] [Full Text] [Related]

  • 15. Mechanism of memantine block of NMDA-activated channels in rat retinal ganglion cells: uncompetitive antagonism.
    Chen HS, Lipton SA.
    J Physiol; 1997 Feb 15; 499 ( Pt 1)(Pt 1):27-46. PubMed ID: 9061638
    [Abstract] [Full Text] [Related]

  • 16. The in vivo relevance of the varied channel-blocking properties of uncompetitive NMDA antagonists: tests on spinal neurones.
    Jones MW, McClean M, Parsons CG, Headley PM.
    Neuropharmacology; 2001 Jul 15; 41(1):50-61. PubMed ID: 11445185
    [Abstract] [Full Text] [Related]

  • 17. Whole cell and single channel analysis of the kinetics of glycine-sensitive N-methyl-D-aspartate receptor desensitization.
    Parsons CG, Zong X, Lux HD.
    Br J Pharmacol; 1993 May 15; 109(1):213-21. PubMed ID: 8098640
    [Abstract] [Full Text] [Related]

  • 18. A novel class of amino-alkylcyclohexanes as uncompetitive, fast, voltage-dependent, N-methyl-D-aspartate (NMDA) receptor antagonists--in vitro characterization.
    Gilling K, Jatzke C, Wollenburg C, Vanejevs M, Kauss V, Jirgensons A, Parsons CG.
    J Neural Transm (Vienna); 2007 May 15; 114(12):1529-37. PubMed ID: 17728997
    [Abstract] [Full Text] [Related]

  • 19. Quinoxaline derivatives: structure-activity relationships and physiological implications of inhibition of N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor-mediated currents and synaptic potentials.
    Randle JC, Guet T, Bobichon C, Moreau C, Curutchet P, Lambolez B, de Carvalho LP, Cordi A, Lepagnol JM.
    Mol Pharmacol; 1992 Feb 15; 41(2):337-45. PubMed ID: 1371583
    [Abstract] [Full Text] [Related]

  • 20. Amino-alkyl-cyclohexanes are novel uncompetitive NMDA receptor antagonists with strong voltage-dependency and fast blocking kinetics: in vitro and in vivo characterization.
    Parsons CG, Danysz W, Bartmann A, Spielmanns P, Frankiewicz T, Hesselink M, Eilbacher B, Quack G.
    Neuropharmacology; 1999 Jan 15; 38(1):85-108. PubMed ID: 10193901
    [Abstract] [Full Text] [Related]

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