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Journal Abstract Search

164 related items for PubMed ID: 8164262

  • 1. Dibasic (amidinoaryl)propanoic acid derivatives as novel blood coagulation factor Xa inhibitors.
    Nagahara T, Yokoyama Y, Inamura K, Katakura S, Komoriya S, Yamaguchi H, Hara T, Iwamoto M.
    J Med Chem; 1994 Apr 15; 37(8):1200-7. PubMed ID: 8164262
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  • 2. Design, synthesis and biological activity of amidinobicyclic compounds (derivatives of DX-9065a) as factor Xa inhibitors: SAR study of S1 and aryl binding sites.
    Komoriya S, Kanaya N, Nagahara T, Yokoyama A, Inamura K, Yokoyama Y, Katakura S, Hara T.
    Bioorg Med Chem; 2004 May 01; 12(9):2099-114. PubMed ID: 15080912
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  • 3. Antithrombotic and hemorrhagic effects of DX-9065a, a direct and selective factor Xa inhibitor: comparison with a direct thrombin inhibitor and antithrombin III-dependent anticoagulants.
    Morishima Y, Tanabe K, Terada Y, Hara T, Kunitada S.
    Thromb Haemost; 1997 Nov 01; 78(5):1366-71. PubMed ID: 9408021
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  • 4. Inactivation of factor Xa by the synthetic inhibitor DX-9065a causes strong anticoagulant and antiplatelet actions in human blood.
    Kaiser B, Jeske W, Walenga JM, Fareed J.
    Blood Coagul Fibrinolysis; 1999 Dec 01; 10(8):495-501. PubMed ID: 10636461
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  • 6. Effects of DX-9065a, an inhibitor of factor Xa, on ellagic acid-induced plantar skin thrombosis assessed in tetrodotoxin- and N(omega)-nitro-L-arginine-treated rats.
    Chino D, Fujita Y, Ishii K, Nakayama K.
    J Pharmacol Sci; 2003 Apr 01; 91(4):319-29. PubMed ID: 12719661
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  • 8. A specific inhibitor of factor Xa, DX-9065a, exerts effective protection against experimental tumor induced disseminated intravascular coagulation in rats.
    Tanabe K, Terada Y, Shibutani T, Kunitada S, Kondo T.
    Thromb Res; 1999 Oct 15; 96(2):135-43. PubMed ID: 10574591
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  • 11. Inhibition of thrombin generation in plasma by inhibitors of factor Xa.
    Prasa D, Svendsen L, Stürzebecher J.
    Thromb Haemost; 1997 Oct 15; 78(4):1215-20. PubMed ID: 9364987
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  • 12. DX-9065a, a new synthetic, potent anticoagulant and selective inhibitor for factor Xa.
    Hara T, Yokoyama A, Ishihara H, Yokoyama Y, Nagahara T, Iwamoto M.
    Thromb Haemost; 1994 Mar 15; 71(3):314-9. PubMed ID: 8029795
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  • 13. Evaluation of proposed modes of binding of (2S)-2-[4-[[(3S)-1-acetimidoyl-3-pyrrolidinyl]oxy]phenyl]-3-(7-am idino- 2- naphthyl)propanoic acid hydrochloride and some analogs to factor Xa using a comparative molecular field analysis.
    Vaz RJ, McLean LR, Pelton JT.
    J Comput Aided Mol Des; 1998 Mar 15; 12(2):99-110. PubMed ID: 9690170
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  • 14. Discovery of N-[(1R,2S,5S)-2-{[(5-chloroindol-2-yl)carbonyl]amino}-5-(dimethylcarbamoyl)cyclohexyl]-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide hydrochloride: a novel, potent and orally active direct inhibitor of factor Xa.
    Nagata T, Yoshino T, Haginoya N, Yoshikawa K, Nagamochi M, Kobayashi S, Komoriya S, Yokomizo A, Muto R, Yamaguchi M, Osanai K, Suzuki M, Kanno H.
    Bioorg Med Chem; 2009 Feb 01; 17(3):1193-206. PubMed ID: 19128974
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  • 18. Design, synthesis and biological activity of YM-60828 derivatives: potent and orally-bioavailable factor Xa inhibitors based on naphthoanilide and naphthalensulfonanilide templates.
    Hirayama F, Koshio H, Ishihara T, Watanuki S, Hachiya S, Kaizawa H, Kuramochi T, Katayama N, Kurihara H, Taniuchi Y, Sato K, Sakai-Moritani Y, Kaku S, Kawasaki T, Matsumoto Y, Sakamoto S, Tsukamoto S.
    Bioorg Med Chem; 2002 Aug 01; 10(8):2597-610. PubMed ID: 12057649
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  • 19. Global anticoagulant effects of a synthetic anti-factor Xa inhibitor (DX-9065a): implications for interventional use.
    Tobu M, Iqbal O, Ma Q, Schultz C, Jeske W, Hoppensteadt D, Lewis B, Fareed D, Fareed J.
    Clin Appl Thromb Hemost; 2003 Jan 01; 9(1):1-17. PubMed ID: 12643318
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