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480 related items for PubMed ID: 8168639
1. Human islet amyloid polypeptide accumulates at similar sites in islets of transgenic mice and humans. de Koning EJ, Höppener JW, Verbeek JS, Oosterwijk C, van Hulst KL, Baker CA, Lips CJ, Morris JF, Clark A. Diabetes; 1994 May; 43(5):640-4. PubMed ID: 8168639 [Abstract] [Full Text] [Related]
2. Intra- and extracellular amyloid fibrils are formed in cultured pancreatic islets of transgenic mice expressing human islet amyloid polypeptide. de Koning EJ, Morris ER, Hofhuis FM, Posthuma G, Höppener JW, Morris JF, Capel PJ, Clark A, Verbeek JS. Proc Natl Acad Sci U S A; 1994 Aug 30; 91(18):8467-71. PubMed ID: 8078905 [Abstract] [Full Text] [Related]
3. Formation of islet amyloid fibrils in beta-secretory granules of transgenic mice expressing human islet amyloid polypeptide/amylin. Yagui K, Yamaguchi T, Kanatsuka A, Shimada F, Huang CI, Tokuyama Y, Ohsawa H, Yamamura K, Miyazaki J, Mikata A. Eur J Endocrinol; 1995 Apr 30; 132(4):487-96. PubMed ID: 7711888 [Abstract] [Full Text] [Related]
4. Pancreatic beta-cell granule peptides form heteromolecular complexes which inhibit islet amyloid polypeptide fibril formation. Jaikaran ET, Nilsson MR, Clark A. Biochem J; 2004 Feb 01; 377(Pt 3):709-16. PubMed ID: 14565847 [Abstract] [Full Text] [Related]
5. Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology. Jaikaran ET, Clark A. Biochim Biophys Acta; 2001 Nov 29; 1537(3):179-203. PubMed ID: 11731221 [Abstract] [Full Text] [Related]
6. Pancreatic expression and secretion of human islet amyloid polypeptide in a transgenic mouse. D'Alessio DA, Verchere CB, Kahn SE, Hoagland V, Baskin DG, Palmiter RD, Ensinck JW. Diabetes; 1994 Dec 29; 43(12):1457-61. PubMed ID: 7958499 [Abstract] [Full Text] [Related]
7. beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes. Andrikopoulos S, Verchere CB, Terauchi Y, Kadowaki T, Kahn SE. Diabetes; 2000 Dec 29; 49(12):2056-62. PubMed ID: 11118007 [Abstract] [Full Text] [Related]
8. Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide. Janson J, Soeller WC, Roche PC, Nelson RT, Torchia AJ, Kreutter DK, Butler PC. Proc Natl Acad Sci U S A; 1996 Jul 09; 93(14):7283-8. PubMed ID: 8692984 [Abstract] [Full Text] [Related]
9. [Construction of transgenic mouse system expressing human islet amyloid polypeptide (IAPP)/amylin]. Yagui K, Kanatsuka A, Makino H. Nihon Rinsho; 1994 Oct 09; 52(10):2746-50. PubMed ID: 7983808 [Abstract] [Full Text] [Related]
11. Effects of free fatty acid on polymerization of islet amyloid polypeptide (IAPP) in vitro and on amyloid fibril formation in cultivated isolated islets of transgenic mice overexpressing human IAPP. Ma Z, Westermark GT. Mol Med; 2002 Dec 09; 8(12):863-8. PubMed ID: 12606822 [Abstract] [Full Text] [Related]
12. An in vitro model of early islet amyloid polypeptide (IAPP) fibrillogenesis using human IAPP-transgenic mouse islets. Henson MS, Buman BL, Jordan K, Rahrmann EP, Hardy RM, Johnson KH, O'Brien TD. Amyloid; 2006 Dec 09; 13(4):250-9. PubMed ID: 17107885 [Abstract] [Full Text] [Related]
14. Differences in amyloid deposition in islets of transgenic mice expressing human islet amyloid polypeptide versus human islets implanted into nude mice. Westermark G, Westermark P, Eizirik DL, Hellerström C, Fox N, Steiner DF, Andersson A. Metabolism; 1999 Apr 09; 48(4):448-54. PubMed ID: 10206436 [Abstract] [Full Text] [Related]