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480 related items for PubMed ID: 8168639

  • 21. Resident macrophages mediate islet amyloid polypeptide-induced islet IL-1β production and β-cell dysfunction.
    Westwell-Roper CY, Ehses JA, Verchere CB.
    Diabetes; 2014 May; 63(5):1698-711. PubMed ID: 24222351
    [Abstract] [Full Text] [Related]

  • 22. Comparative molecular dynamics study of human islet amyloid polypeptide (IAPP) and rat IAPP oligomers.
    Liang G, Zhao J, Yu X, Zheng J.
    Biochemistry; 2013 Feb 12; 52(6):1089-100. PubMed ID: 23331123
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  • 23. Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model.
    Höppener JW, Oosterwijk C, Nieuwenhuis MG, Posthuma G, Thijssen JH, Vroom TM, Ahrén B, Lips CJ.
    Diabetologia; 1999 Apr 12; 42(4):427-34. PubMed ID: 10230646
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  • 24. IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice.
    Westwell-Roper CY, Chehroudi CA, Denroche HC, Courtade JA, Ehses JA, Verchere CB.
    Diabetologia; 2015 Mar 12; 58(3):575-85. PubMed ID: 25491100
    [Abstract] [Full Text] [Related]

  • 25. Islet amyloid polypeptide: a review of its biology and potential roles in the pathogenesis of diabetes mellitus.
    O'Brien TD, Butler PC, Westermark P, Johnson KH.
    Vet Pathol; 1993 Jul 12; 30(4):317-32. PubMed ID: 8212454
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  • 26. Postnatally disturbed pancreatic islet cell distribution in human islet amyloid polypeptide transgenic mice.
    Wong HY, Ahrén B, Lips CJ, Höppener JW, Sundler F.
    Regul Pept; 2003 May 15; 113(1-3):89-94. PubMed ID: 12686466
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  • 27. The β-cell assassin: IAPP cytotoxicity.
    Raleigh D, Zhang X, Hastoy B, Clark A.
    J Mol Endocrinol; 2017 Oct 15; 59(3):R121-R140. PubMed ID: 28811318
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  • 28. Islet amyloid polypeptide (IAPP) and pancreatic islet amyloid deposition in diabetic and non-diabetic patients.
    Narita R, Toshimori H, Nakazato M, Kuribayashi T, Toshimori T, Kawabata K, Takahashi K, Masukura S.
    Diabetes Res Clin Pract; 1992 Jan 15; 15(1):3-14. PubMed ID: 1541232
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  • 29. Macrophages and pancreatic islet amyloidosis.
    de Koning EJ, van den Brand JJ, Mott VL, Chargé SB, Hansen BC, Bodkin NL, Morris JF, Clark A.
    Amyloid; 1998 Dec 15; 5(4):247-54. PubMed ID: 10036582
    [Abstract] [Full Text] [Related]

  • 30. Islet pathology of non-insulin-dependent diabetes mellitus (NIDDM).
    Westermark P.
    Diabet Med; 1996 Sep 15; 13(9 Suppl 6):S46-8. PubMed ID: 8894481
    [Abstract] [Full Text] [Related]

  • 31. Islet amyloid in type 2 (non-insulin-dependent) diabetes.
    Clark A, Chargé SB, Badman MK, de Koning EJ.
    APMIS; 1996 Jan 15; 104(1):12-8. PubMed ID: 8645452
    [Abstract] [Full Text] [Related]

  • 32. Induction of negative curvature as a mechanism of cell toxicity by amyloidogenic peptides: the case of islet amyloid polypeptide.
    Smith PE, Brender JR, Ramamoorthy A.
    J Am Chem Soc; 2009 Apr 01; 131(12):4470-8. PubMed ID: 19278224
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  • 33. A single mutation in the nonamyloidogenic region of islet amyloid polypeptide greatly reduces toxicity.
    Brender JR, Hartman K, Reid KR, Kennedy RT, Ramamoorthy A.
    Biochemistry; 2008 Dec 02; 47(48):12680-8. PubMed ID: 18989933
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  • 34. Structural and energetic insight into the cross-seeding amyloid assemblies of human IAPP and rat IAPP.
    Zhang M, Hu R, Liang G, Chang Y, Sun Y, Peng Z, Zheng J.
    J Phys Chem B; 2014 Jun 26; 118(25):7026-36. PubMed ID: 24892388
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  • 35. Two novel immortal pancreatic beta-cell lines expressing and secreting human islet amyloid polypeptide do not spontaneously develop islet amyloid.
    Andrikopoulos S, Verchere CB, Teague JC, Howell WM, Fujimoto WY, Wight TN, Kahn SE.
    Diabetes; 1999 Oct 26; 48(10):1962-70. PubMed ID: 10512360
    [Abstract] [Full Text] [Related]

  • 36. Islet amyloid polypeptide in pancreatic islets from type 2 diabetic subjects.
    Tomita T.
    Islets; 2012 Oct 26; 4(3):223-32. PubMed ID: 22847497
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  • 37. Expression of human islet amyloid polypeptide/amylin impairs insulin secretion in mouse pancreatic beta cells.
    Tokuyama T, Yagui K, Yamaguchi T, Huang CI, Kuramoto N, Shimada F, Miyazaki J, Horie H, Saito Y, Makino H, Kanatsuka A.
    Metabolism; 1997 Sep 26; 46(9):1044-51. PubMed ID: 9284894
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  • 38. Immunolocalization of islet amyloid polypeptide (IAPP) in pancreatic beta cells by means of peroxidase-antiperoxidase (PAP) and protein A-gold techniques.
    Johnson KH, O'Brien TD, Hayden DW, Jordan K, Ghobrial HK, Mahoney WC, Westermark P.
    Am J Pathol; 1988 Jan 26; 130(1):1-8. PubMed ID: 3276206
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  • 39. The islet tissue plasminogen activator/plasmin system is upregulated with human islet amyloid polypeptide aggregation and protects beta cells from aggregation-induced toxicity.
    Esser N, Hogan MF, Templin AT, Akter R, Fountaine BS, Castillo JJ, El-Osta A, Manathunga L, Zhyvoloup A, Raleigh DP, Zraika S, Hull RL, Kahn SE.
    Diabetologia; 2024 Sep 26; 67(9):1897-1911. PubMed ID: 39245780
    [Abstract] [Full Text] [Related]

  • 40. Human islet amyloid polypeptide transgenic mice: in vivo and ex vivo models for the role of hIAPP in type 2 diabetes mellitus.
    Höppener JW, Jacobs HM, Wierup N, Sotthewes G, Sprong M, de Vos P, Berger R, Sundler F, Ahrén B.
    Exp Diabetes Res; 2008 Sep 26; 2008():697035. PubMed ID: 18497871
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