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207 related items for PubMed ID: 8170469

  • 1. Identification of a point mutation in the thyrotropin receptor of the hyt/hyt hypothyroid mouse.
    Stein SA, Oates EL, Hall CR, Grumbles RM, Fernandez LM, Taylor NA, Puett D, Jin S.
    Mol Endocrinol; 1994 Feb; 8(2):129-38. PubMed ID: 8170469
    [Abstract] [Full Text] [Related]

  • 2. The thyrotropin (TSH) receptor transmembrane domain mutation (Pro556-Leu) in the hypothyroid hyt/hyt mouse results in plasma membrane targeting but defective TSH binding.
    Gu WX, Du GG, Kopp P, Rentoumis A, Albanese C, Kohn LD, Madison LD, Jameson JL.
    Endocrinology; 1995 Jul; 136(7):3146-53. PubMed ID: 7789342
    [Abstract] [Full Text] [Related]

  • 3. Expression of functional TSH receptor in white adipose tissues of hyt/hyt mice induces lipolysis in vivo.
    Endo T, Kobayashi T.
    Am J Physiol Endocrinol Metab; 2012 Jun 15; 302(12):E1569-75. PubMed ID: 22496347
    [Abstract] [Full Text] [Related]

  • 4. Mutations of the human thyrotropin receptor gene causing thyroid hypoplasia and persistent congenital hypothyroidism.
    Biebermann H, Schöneberg T, Krude H, Schultz G, Gudermann T, Grüters A.
    J Clin Endocrinol Metab; 1997 Oct 15; 82(10):3471-80. PubMed ID: 9329388
    [Abstract] [Full Text] [Related]

  • 5. The site of the molecular defect in the thyroid gland of the hyt/hyt mouse: abnormalities in the TSH receptor-G protein complex.
    Stein SA, Zakarija M, McKenzie JM, Shanklin DR, Palnitkar MB, Adams PM.
    Thyroid; 1991 Oct 15; 1(3):257-66. PubMed ID: 1668617
    [Abstract] [Full Text] [Related]

  • 6. Thyroid-stimulating hormone receptor in brown adipose tissue is involved in the regulation of thermogenesis.
    Endo T, Kobayashi T.
    Am J Physiol Endocrinol Metab; 2008 Aug 15; 295(2):E514-8. PubMed ID: 18559984
    [Abstract] [Full Text] [Related]

  • 7. Dominant negative effect of mutated thyroid stimulating hormone receptor (P556L) causes hypothyroidism in C.RF-Tshr(hyt/wild) mice.
    Endo T, Kobayashi T.
    PLoS One; 2012 Aug 15; 7(8):e42358. PubMed ID: 22916127
    [Abstract] [Full Text] [Related]

  • 8. Biology of the congenitally hypothyroid hyt/hyt mouse.
    Biesiada E, Adams PM, Shanklin DR, Bloom GS, Stein SA.
    Adv Neuroimmunol; 1996 Aug 15; 6(4):309-46. PubMed ID: 9183515
    [Abstract] [Full Text] [Related]

  • 9. Substitutions of different regions of the third cytoplasmic loop of the thyrotropin (TSH) receptor have selective effects on constitutive, TSH-, and TSH receptor autoantibody-stimulated phosphoinositide and 3',5'-cyclic adenosine monophosphate signal generation.
    Kosugi S, Okajima F, Ban T, Hidaka A, Shenker A, Kohn LD.
    Mol Endocrinol; 1993 Aug 15; 7(8):1009-20. PubMed ID: 7901757
    [Abstract] [Full Text] [Related]

  • 10. Excess TSH causes abnormal skeletal development in young mice with hypothyroidism via suppressive effects on the growth plate.
    Endo T, Kobayashi T.
    Am J Physiol Endocrinol Metab; 2013 Sep 01; 305(5):E660-6. PubMed ID: 23880310
    [Abstract] [Full Text] [Related]

  • 11. Mutations in the mouse TSH receptor equivalent to human constitutively activating TSH receptor mutations also cause constitutive activity.
    Neumann S, Krohn K, Chey S, Paschke R.
    Horm Metab Res; 2001 May 01; 33(5):263-9. PubMed ID: 11440271
    [Abstract] [Full Text] [Related]

  • 12. Identification of thyroid-stimulating antibody-specific interaction sites in the N-terminal region of the thyrotropin receptor.
    Kosugi S, Ban T, Kohn LD.
    Mol Endocrinol; 1993 Jan 01; 7(1):114-30. PubMed ID: 8095322
    [Abstract] [Full Text] [Related]

  • 13. Evaluation and characterization of the hyt/hyt hypothyroid mouse. II. Abnormalities of TSH and the thyroid gland.
    Stein SA, Shanklin DR, Krulich L, Roth MG, Chubb CM, Adams PM.
    Neuroendocrinology; 1989 May 01; 49(5):509-19. PubMed ID: 2725843
    [Abstract] [Full Text] [Related]

  • 14. Identification of a new thyrotropin receptor germline mutation (Leu629Phe) in a family with neonatal onset of autosomal dominant nonautoimmune hyperthyroidism.
    Führer D, Wonerow P, Willgerodt H, Paschke R.
    J Clin Endocrinol Metab; 1997 Dec 01; 82(12):4234-8. PubMed ID: 9398746
    [Abstract] [Full Text] [Related]

  • 15. Delayed ultrastructural lung maturation in the fetal and newborn hypothyroid (Hyt/Hyt) mouse.
    deMello DE, Heyman S, Govindarajan R, Sosenko IR, Devaskar UP.
    Pediatr Res; 1994 Sep 01; 36(3):380-6. PubMed ID: 7808836
    [Abstract] [Full Text] [Related]

  • 16. Congenital hypothyroidism with impaired thyroid response to thyrotropin (TSH) and absent circulating thyroglobulin: evidence for a new inactivating mutation of the TSH receptor gene.
    Tonacchera M, Agretti P, Pinchera A, Rosellini V, Perri A, Collecchi P, Vitti P, Chiovato L.
    J Clin Endocrinol Metab; 2000 Mar 01; 85(3):1001-8. PubMed ID: 10720030
    [Abstract] [Full Text] [Related]

  • 17. Development of auditory brainstem responses (ABRs) in Tshr mutant mice derived from euthyroid and hypothyroid dams.
    Sprenkle PM, McGee J, Bertoni JM, Walsh EJ.
    J Assoc Res Otolaryngol; 2001 Dec 01; 2(4):330-47. PubMed ID: 11833607
    [Abstract] [Full Text] [Related]

  • 18. Single strand DNA-binding proteins and thyroid transcription factor-1 conjointly regulate thyrotropin receptor gene expression.
    Shimura H, Shimura Y, Ohmori M, Ikuyama S, Kohn LD.
    Mol Endocrinol; 1995 May 01; 9(5):527-39. PubMed ID: 7565801
    [Abstract] [Full Text] [Related]

  • 19. Identification of TSH receptor mutations in three families with resistance to TSH.
    Tonacchera M, Di Cosmo C, De Marco G, Agretti P, Banco M, Perri A, Gianetti E, Montanelli L, Vitti P, Pinchera A.
    Clin Endocrinol (Oxf); 2007 Nov 01; 67(5):712-8. PubMed ID: 17697008
    [Abstract] [Full Text] [Related]

  • 20. Sequence analysis of the thyrotropin (TSH) receptor gene in congenital primary hypothyroidism associated with TSH unresponsiveness.
    Takeshita A, Nagayama Y, Yamashita S, Takamatsu J, Ohsawa N, Maesaka H, Tachibana K, Tokuhiro E, Ashizawa K, Yokoyama N.
    Thyroid; 1994 Nov 01; 4(3):255-9. PubMed ID: 7833660
    [Abstract] [Full Text] [Related]

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