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174 related items for PubMed ID: 8175732

  • 1. A beta-adrenergic receptor kinase dominant negative mutant attenuates desensitization of the beta 2-adrenergic receptor.
    Kong G, Penn R, Benovic JL.
    J Biol Chem; 1994 May 06; 269(18):13084-7. PubMed ID: 8175732
    [Abstract] [Full Text] [Related]

  • 2. Role of beta ARK in long-term agonist-promoted desensitisation of the beta 2-adrenergic receptor.
    McGraw DW, Donnelly ET, Eason MG, Green SA, Liggett SB.
    Cell Signal; 1998 Mar 06; 10(3):197-204. PubMed ID: 9607143
    [Abstract] [Full Text] [Related]

  • 3. The palmitoylation state of the beta(2)-adrenergic receptor regulates the synergistic action of cyclic AMP-dependent protein kinase and beta-adrenergic receptor kinase involved in its phosphorylation and desensitization.
    Moffett S, Rousseau G, Lagacé M, Bouvier M.
    J Neurochem; 2001 Jan 06; 76(1):269-79. PubMed ID: 11146000
    [Abstract] [Full Text] [Related]

  • 4. Role of phosphorylation in agonist-promoted beta 2-adrenergic receptor sequestration. Rescue of a sequestration-defective mutant receptor by beta ARK1.
    Ferguson SS, Ménard L, Barak LS, Koch WJ, Colapietro AM, Caron MG.
    J Biol Chem; 1995 Oct 20; 270(42):24782-9. PubMed ID: 7559596
    [Abstract] [Full Text] [Related]

  • 5. Phosphorylation and desensitization of the human beta 1-adrenergic receptor. Involvement of G protein-coupled receptor kinases and cAMP-dependent protein kinase.
    Freedman NJ, Liggett SB, Drachman DE, Pei G, Caron MG, Lefkowitz RJ.
    J Biol Chem; 1995 Jul 28; 270(30):17953-61. PubMed ID: 7629102
    [Abstract] [Full Text] [Related]

  • 6. Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms.
    Pitcher J, Lohse MJ, Codina J, Caron MG, Lefkowitz RJ.
    Biochemistry; 1992 Mar 31; 31(12):3193-7. PubMed ID: 1348186
    [Abstract] [Full Text] [Related]

  • 7. Four consecutive serines in the third intracellular loop are the sites for beta-adrenergic receptor kinase-mediated phosphorylation and desensitization of the alpha 2A-adrenergic receptor.
    Eason MG, Moreira SP, Liggett SB.
    J Biol Chem; 1995 Mar 03; 270(9):4681-8. PubMed ID: 7876239
    [Abstract] [Full Text] [Related]

  • 8. Beta-adrenergic receptor kinase. Agonist-dependent receptor binding promotes kinase activation.
    Chen CY, Dion SB, Kim CM, Benovic JL.
    J Biol Chem; 1993 Apr 15; 268(11):7825-31. PubMed ID: 8096517
    [Abstract] [Full Text] [Related]

  • 9. Oligodeoxynucleotides antisense to mRNA encoding protein kinase A, protein kinase C, and beta-adrenergic receptor kinase reveal distinctive cell-type-specific roles in agonist-induced desensitization.
    Shih M, Malbon CC.
    Proc Natl Acad Sci U S A; 1994 Dec 06; 91(25):12193-7. PubMed ID: 7991605
    [Abstract] [Full Text] [Related]

  • 10. Characterization and inhibition of beta-adrenergic receptor kinase in intact myocytes.
    Laugwitz KL, Kronsbein K, Schmitt M, Hoffmann K, Seyfarth M, Schömig A, Ungerer M.
    Cardiovasc Res; 1997 Aug 06; 35(2):324-33. PubMed ID: 9349395
    [Abstract] [Full Text] [Related]

  • 11. c-Src tyrosine kinase binds the beta 2-adrenergic receptor via phospho-Tyr-350, phosphorylates G-protein-linked receptor kinase 2, and mediates agonist-induced receptor desensitization.
    Fan G, Shumay E, Malbon CC, Wang H.
    J Biol Chem; 2001 Apr 20; 276(16):13240-7. PubMed ID: 11278940
    [Abstract] [Full Text] [Related]

  • 12. Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism.
    Liggett SB, Ostrowski J, Chesnut LC, Kurose H, Raymond JR, Caron MG, Lefkowitz RJ.
    J Biol Chem; 1992 Mar 05; 267(7):4740-6. PubMed ID: 1311318
    [Abstract] [Full Text] [Related]

  • 13. Differences in desensitization between human beta 1- and beta 2-adrenergic receptors stably expressed in transfected hamster cells.
    Zhou XM, Pak M, Wang Z, Fishman PH.
    Cell Signal; 1995 Mar 05; 7(3):207-17. PubMed ID: 7662509
    [Abstract] [Full Text] [Related]

  • 14. The beta-adrenergic receptor kinase: role in homologous desensitization in S49 lymphoma cells.
    Strasser RH, Benovic JL, Lefkowitz RJ, Caron MG.
    Adv Exp Med Biol; 1988 Mar 05; 231():503-17. PubMed ID: 2843012
    [Abstract] [Full Text] [Related]

  • 15. The full-length, cytoplasmic C-terminus of the beta 2-adrenergic receptor expressed in E. coli acts as a substrate for phosphorylation by protein kinase A, insulin receptor tyrosine kinase, GRK2, but not protein kinase C and suppresses desensitization when expressed in vivo.
    Doronin S, Lin F, Wang HY, Malbon CC.
    Protein Expr Purif; 2000 Dec 05; 20(3):451-61. PubMed ID: 11087685
    [Abstract] [Full Text] [Related]

  • 16. Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase.
    Roth NS, Campbell PT, Caron MG, Lefkowitz RJ, Lohse MJ.
    Proc Natl Acad Sci U S A; 1991 Jul 15; 88(14):6201-4. PubMed ID: 1648731
    [Abstract] [Full Text] [Related]

  • 17. The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2.
    Kwatra MM, Schwinn DA, Schreurs J, Blank JL, Kim CM, Benovic JL, Krause JE, Caron MG, Lefkowitz RJ.
    J Biol Chem; 1993 May 05; 268(13):9161-4. PubMed ID: 7683643
    [Abstract] [Full Text] [Related]

  • 18. High expression of beta-adrenergic receptor kinase in human peripheral blood leukocytes. Isoproterenol and platelet activating factor can induce kinase translocation.
    Chuang TT, Sallese M, Ambrosini G, Parruti G, De Blasi A.
    J Biol Chem; 1992 Apr 05; 267(10):6886-92. PubMed ID: 1339451
    [Abstract] [Full Text] [Related]

  • 19. Mechanism of beta-adrenergic receptor kinase activation by G proteins.
    Kim CM, Dion SB, Benovic JL.
    J Biol Chem; 1993 Jul 25; 268(21):15412-8. PubMed ID: 8393441
    [Abstract] [Full Text] [Related]

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