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Journal Abstract Search

186 related items for PubMed ID: 8182711

  • 1. Synthesis and structure-activity relationships of deazaxanthines: analogs of potent A1- and A2-adenosine receptor antagonists.
    Grahner B, Winiwarter S, Lanzner W, Müller CE.
    J Med Chem; 1994 May 13; 37(10):1526-34. PubMed ID: 8182711
    [Abstract] [Full Text] [Related]

  • 2. 1,8-disubstituted xanthine derivatives: synthesis of potent A2B-selective adenosine receptor antagonists.
    Hayallah AM, Sandoval-Ramírez J, Reith U, Schobert U, Preiss B, Schumacher B, Daly JW, Müller CE.
    J Med Chem; 2002 Mar 28; 45(7):1500-10. PubMed ID: 11906291
    [Abstract] [Full Text] [Related]

  • 3. Xanthines with C8 chiral substituents as potent and selective adenosine A1 antagonists.
    Peet NP, Lentz NL, Dudley MW, Ogden AM, McCarty DR, Racke MM.
    J Med Chem; 1993 Dec 10; 36(25):4015-20. PubMed ID: 8258823
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  • 6. 1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships.
    Stefanachi A, Nicolotti O, Leonetti F, Cellamare S, Campagna F, Loza MI, Brea JM, Mazza F, Gavuzzo E, Carotti A.
    Bioorg Med Chem; 2008 Nov 15; 16(22):9780-9. PubMed ID: 18938084
    [Abstract] [Full Text] [Related]

  • 7. Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.
    Kim SA, Marshall MA, Melman N, Kim HS, Müller CE, Linden J, Jacobson KA.
    J Med Chem; 2002 May 23; 45(11):2131-8. PubMed ID: 12014951
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  • 8. 8-Azaxanthine derivatives as antagonists of adenosine receptors.
    Franchetti P, Messini L, Cappellacci L, Grifantini M, Lucacchini A, Martini C, Senatore G.
    J Med Chem; 1994 Sep 02; 37(18):2970-5. PubMed ID: 8071944
    [Abstract] [Full Text] [Related]

  • 9. Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors.
    Jacobson KA, Shi D, Gallo-Rodriguez C, Manning M, Müller C, Daly JW, Neumeyer JL, Kiriasis L, Pfleiderer W.
    J Med Chem; 1993 Sep 03; 36(18):2639-44. PubMed ID: 8410976
    [Abstract] [Full Text] [Related]

  • 10. Aza-analogs of 8-styrylxanthines as A2A-adenosine receptor antagonists.
    Müller CE, Sauer R, Geis U, Frobenius W, Talik P, Pawlowski M.
    Arch Pharm (Weinheim); 1997 Jun 03; 330(6):181-9. PubMed ID: 9264243
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and pharmacological evaluation of novel 1,3,8- and 1,3,7,8-substituted xanthines as adenosine receptor antagonists.
    Rodríguez-Borges JE, García-Mera X, Balo MC, Brea J, Caamaño O, Fernández F, López C, Loza MI, Nieto MI.
    Bioorg Med Chem; 2010 Mar 01; 18(5):2001-9. PubMed ID: 20137957
    [Abstract] [Full Text] [Related]

  • 12. Structure-activity relationships in a series of 8-substituted xanthines as A1-adenosine receptor antagonists.
    Strappaghetti G, Corsano S, Barbaro R, Giannaccini G, Betti L.
    Bioorg Med Chem; 2001 Mar 01; 9(3):575-83. PubMed ID: 11310591
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  • 13. Synthesis and pharmacological evaluation of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists.
    Balo MC, Brea J, Caamaño O, Fernández F, García-Mera X, López C, Loza MI, Nieto MI, Rodríguez-Borges JE.
    Bioorg Med Chem; 2009 Sep 15; 17(18):6755-60. PubMed ID: 19682912
    [Abstract] [Full Text] [Related]

  • 14. Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptors.
    Müller CE, Shi D, Manning M, Daly JW.
    J Med Chem; 1993 Oct 29; 36(22):3341-9. PubMed ID: 8230124
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and biological evaluation of the enantiomers of the potent and selective A1-adenosine antagonist 1,3-dipropyl-8-[2-(5,6-epoxynorbonyl)]-xanthine.
    Pfister JR, Belardinelli L, Lee G, Lum RT, Milner P, Stanley WC, Linden J, Baker SP, Schreiner G.
    J Med Chem; 1997 Jun 06; 40(12):1773-8. PubMed ID: 9191953
    [Abstract] [Full Text] [Related]

  • 16. Chiral pyrrolo[2,3-d]pyrimidine and pyrimido[4,5-b]indole derivatives: structure-activity relationships of potent, highly stereoselective A1-adenosine receptor antagonists.
    Müller CE, Geis U, Grahner B, Lanzner W, Eger K.
    J Med Chem; 1996 Jun 21; 39(13):2482-91. PubMed ID: 8691445
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and pharmacological evaluation of novel substituted 9-deazaxanthines as A2B receptor antagonists.
    Nieto MI, Balo MC, Brea J, Caamaño O, Fernández F, García-Mera X, López C, Loza MI, Rodríguez-Borges JE, Vidal B.
    Eur J Med Chem; 2010 Jul 21; 45(7):2884-92. PubMed ID: 20371139
    [Abstract] [Full Text] [Related]

  • 18. 1,3,7-Triethyl-substituted xanthines--possess nanomolar affinity for the adenosine A1 receptor.
    Van der Walt MM, Terre'Blanche G.
    Bioorg Med Chem; 2015 Oct 15; 23(20):6641-9. PubMed ID: 26392370
    [Abstract] [Full Text] [Related]

  • 19. Molecular simulation of 8-styrylxanthines.
    Mager PP, Reinhardt R, Richter M, Walther H, Rockel B.
    Drug Des Discov; 1995 Nov 15; 13(2):89-107. PubMed ID: 8872454
    [Abstract] [Full Text] [Related]

  • 20. 8-(Sulfostyryl)xanthines: water-soluble A2A-selective adenosine receptor antagonists.
    Müller CE, Sandoval-Ramírez J, Schobert U, Geis U, Frobenius W, Klotz KN.
    Bioorg Med Chem; 1998 Jun 15; 6(6):707-19. PubMed ID: 9681137
    [Abstract] [Full Text] [Related]

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