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248 related items for PubMed ID: 8193364

  • 1. Novel retinoic acid, 9-cis retinoic acid, in combination with all-trans retinoic acid is an effective inducer of differentiation of retinoic acid-resistant HL-60 cells.
    Kizaki M, Nakajima H, Mori S, Koike T, Morikawa M, Ohta M, Saito M, Koeffler HP, Ikeda Y.
    Blood; 1994 Jun 01; 83(11):3289-97. PubMed ID: 8193364
    [Abstract] [Full Text] [Related]

  • 2. Mechanisms of retinoid resistance in leukemic cells: possible role of cytochrome P450 and P-glycoprotein.
    Kizaki M, Ueno H, Yamazoe Y, Shimada M, Takayama N, Muto A, Matsushita H, Nakajima H, Morikawa M, Koeffler HP, Ikeda Y.
    Blood; 1996 Jan 15; 87(2):725-33. PubMed ID: 8555497
    [Abstract] [Full Text] [Related]

  • 3. Effects of novel RAR- and RXR-selective retinoids on myeloid leukemic proliferation and differentiation in vitro.
    Shiohara M, Dawson MI, Hobbs PD, Sawai N, Higuchi T, Koike K, Komiyama A, Koeffler HP.
    Blood; 1999 Mar 15; 93(6):2057-66. PubMed ID: 10068679
    [Abstract] [Full Text] [Related]

  • 4. 9-cis retinoic acid induces complete remission but does not reverse clinically acquired retinoid resistance in acute promyelocytic leukemia.
    Miller WH, Jakubowski A, Tong WP, Miller VA, Rigas JR, Benedetti F, Gill GM, Truglia JA, Ulm E, Shirley M.
    Blood; 1995 Jun 01; 85(11):3021-7. PubMed ID: 7756637
    [Abstract] [Full Text] [Related]

  • 5. Effects of novel retinoic acid compound, 9-cis-retinoic acid, on proliferation, differentiation, and expression of retinoic acid receptor-alpha and retinoid X receptor-alpha RNA by HL-60 cells.
    Kizaki M, Ikeda Y, Tanosaki R, Nakajima H, Morikawa M, Sakashita A, Koeffler HP.
    Blood; 1993 Dec 15; 82(12):3592-9. PubMed ID: 8260698
    [Abstract] [Full Text] [Related]

  • 6. 1,25-Dihydroxyvitamin D3 induces differentiation of a retinoic acid-resistant acute promyelocytic leukemia cell line (UF-1) associated with expression of p21(WAF1/CIP1) and p27(KIP1).
    Muto A, Kizaki M, Yamato K, Kawai Y, Kamata-Matsushita M, Ueno H, Ohguchi M, Nishihara T, Koeffler HP, Ikeda Y.
    Blood; 1999 Apr 01; 93(7):2225-33. PubMed ID: 10090931
    [Abstract] [Full Text] [Related]

  • 7. 9-cis-retinoic acid: effects on normal and leukemic hematopoiesis in vitro.
    Sakashita A, Kizaki M, Pakkala S, Schiller G, Tsuruoka N, Tomosaki R, Cameron JF, Dawson MI, Koeffler HP.
    Blood; 1993 Feb 15; 81(4):1009-16. PubMed ID: 8427982
    [Abstract] [Full Text] [Related]

  • 8. Mutation in the ligand-binding domain of the retinoic acid receptor alpha in HL-60 leukemic cells resistant to retinoic acid and with increased sensitivity to vitamin D3 analogs.
    Doré BT, Momparler RL.
    Leuk Res; 1996 Sep 15; 20(9):761-9. PubMed ID: 8947586
    [Abstract] [Full Text] [Related]

  • 9. Continuous treatment with all-trans retinoic acid causes a progressive reduction in plasma drug concentrations: implications for relapse and retinoid "resistance" in patients with acute promyelocytic leukemia.
    Muindi J, Frankel SR, Miller WH, Jakubowski A, Scheinberg DA, Young CW, Dmitrovsky E, Warrell RP.
    Blood; 1992 Jan 15; 79(2):299-303. PubMed ID: 1309668
    [Abstract] [Full Text] [Related]

  • 10. Establishment and characterization of a novel acute promyelocytic leukemia cell line (UF-1) with retinoic acid-resistant features.
    Kizaki M, Matsushita H, Takayama N, Muto A, Ueno H, Awaya N, Kawai Y, Asou H, Kamada N, Ikeda Y.
    Blood; 1996 Sep 01; 88(5):1824-33. PubMed ID: 8781440
    [Abstract] [Full Text] [Related]

  • 11. Effects of novel retinoid X receptor-selective ligands on myeloid leukemia differentiation and proliferation in vitro.
    Kizaki M, Dawson MI, Heyman R, Elster E, Morosetti R, Pakkala S, Chen DL, Ueno H, Chao W, Morikawa M, Ikeda Y, Heber D, Pfahl M, Koeffler HP.
    Blood; 1996 Mar 01; 87(5):1977-84. PubMed ID: 8634447
    [Abstract] [Full Text] [Related]

  • 12. Restoration of retinoid sensitivity by MDR1 ribozymes in retinoic acid-resistant myeloid leukemic cells.
    Matsushita H, Kizaki M, Kobayashi H, Ueno H, Muto A, Takayama N, Awaya N, Kinjo K, Hattori Y, Ikeda Y.
    Blood; 1998 Apr 01; 91(7):2452-8. PubMed ID: 9516145
    [Abstract] [Full Text] [Related]

  • 13. The catalytic DNA topoisomerase II inhibitor ICRF-193 and all-trans retinoic acid cooperatively induce granulocytic differentiation of acute promyelocytic leukemia cells: candidate drugs for chemo-differentiation therapy against acute promyelocytic leukemia.
    Niitsu N, Higashihara M, Honma Y.
    Exp Hematol; 2002 Nov 01; 30(11):1273-82. PubMed ID: 12423680
    [Abstract] [Full Text] [Related]

  • 14. Infrequent alterations of the RAR alpha gene in acute myelogenous leukemias, retinoic acid-resistant acute promyelocytic leukemias, myelodysplastic syndromes, and cell lines.
    Morosetti R, Grignani F, Liberatore C, Pelicci PG, Schiller GJ, Kizaki M, Bartram CR, Miller CW, Koeffler HP.
    Blood; 1996 May 15; 87(10):4399-403. PubMed ID: 8639801
    [Abstract] [Full Text] [Related]

  • 15. Combination of a potent 20-epi-vitamin D3 analogue (KH 1060) with 9-cis-retinoic acid irreversibly inhibits clonal growth, decreases bcl-2 expression, and induces apoptosis in HL-60 leukemic cells.
    Elstner E, Linker-Israeli M, Umiel T, Le J, Grillier I, Said J, Shintaku IP, Krajewski S, Reed JC, Binderup L, Koeffler HP.
    Cancer Res; 1996 Aug 01; 56(15):3570-6. PubMed ID: 8758928
    [Abstract] [Full Text] [Related]

  • 16. Myeloid differentiation mediated through retinoic acid receptor/retinoic X receptor (RXR) not RXR/RXR pathway.
    Dawson MI, Elstner E, Kizaki M, Chen DL, Pakkala S, Kerner B, Koeffler HP.
    Blood; 1994 Jul 15; 84(2):446-52. PubMed ID: 8025272
    [Abstract] [Full Text] [Related]

  • 17. A novel retinoic acid receptor (RAR)-selective antagonist inhibits differentiation and apoptosis of HL-60 cells: implications of RARalpha-mediated signals in myeloid leukemic cells.
    Ueno H, Kizaki M, Matsushita H, Muto A, Yamato K, Nishihara T, Hida T, Yoshimura H, Koeffler HP, Ikeda Y.
    Leuk Res; 1998 Jun 15; 22(6):517-25. PubMed ID: 9678718
    [Abstract] [Full Text] [Related]

  • 18. Synergistic decrease of clonal proliferation, induction of differentiation, and apoptosis of acute promyelocytic leukemia cells after combined treatment with novel 20-epi vitamin D3 analogs and 9-cis retinoic acid.
    Elstner E, Linker-Israeli M, Le J, Umiel T, Michl P, Said JW, Binderup L, Reed JC, Koeffler HP.
    J Clin Invest; 1997 Jan 15; 99(2):349-60. PubMed ID: 9006004
    [Abstract] [Full Text] [Related]

  • 19. Induction of differentiation in acute promyelocytic leukemia cells by 9-cis retinoic acid alpha-tocopherol ester (9-cis tretinoin tocoferil).
    Makishima M, Umesono K, Shudo K, Naoe T, Kishi K, Honma Y.
    Blood; 1998 Jun 15; 91(12):4715-26. PubMed ID: 9616170
    [Abstract] [Full Text] [Related]

  • 20. Granulocytic differentiation of human NB4 promyelocytic leukemia cells induced by all-trans retinoic acid metabolites.
    Idres N, Benoît G, Flexor MA, Lanotte M, Chabot GG.
    Cancer Res; 2001 Jan 15; 61(2):700-5. PubMed ID: 11212271
    [Abstract] [Full Text] [Related]


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