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194 related items for PubMed ID: 8196657

  • 1. Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton.
    Prendergast GC, Davide JP, deSolms SJ, Giuliani EA, Graham SL, Gibbs JB, Oliff A, Kohl NE.
    Mol Cell Biol; 1994 Jun; 14(6):4193-202. PubMed ID: 8196657
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  • 2. Resistance of a variant ras-transformed cell line to phenotypic reversion by farnesyl transferase inhibitors.
    Prendergast GC, Davide JP, Lebowitz PF, Wechsler-Reya R, Kohl NE.
    Cancer Res; 1996 Jun 01; 56(11):2626-32. PubMed ID: 8653708
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  • 7. Farnesyltransferase inhibitors are inhibitors of Ras but not R-Ras2/TC21, transformation.
    Carboni JM, Yan N, Cox AD, Bustelo X, Graham SM, Lynch MJ, Weinmann R, Seizinger BR, Der CJ, Barbacid M.
    Oncogene; 1995 May 18; 10(10):1905-13. PubMed ID: 7761092
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  • 8. Reversal of the Ras-induced transformed phenotype by HR12, a novel ras farnesylation inhibitor, is mediated by the Mek/Erk pathway.
    Reuveni H, Geiger T, Geiger B, Levitzki A.
    J Cell Biol; 2000 Dec 11; 151(6):1179-92. PubMed ID: 11121434
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  • 9. Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice.
    Kohl NE, Wilson FR, Mosser SD, Giuliani E, deSolms SJ, Conner MW, Anthony NJ, Holtz WJ, Gomez RP, Lee TJ.
    Proc Natl Acad Sci U S A; 1994 Sep 13; 91(19):9141-5. PubMed ID: 8090782
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  • 12. Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes.
    Lerner EC, Qian Y, Blaskovich MA, Fossum RD, Vogt A, Sun J, Cox AD, Der CJ, Hamilton AD, Sebti SM.
    J Biol Chem; 1995 Nov 10; 270(45):26802-6. PubMed ID: 7592920
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  • 15. [Anti tumor activity of farnesyl transferase inhibitor].
    Yoshimatsu K, Nagasu T.
    Gan To Kagaku Ryoho; 1997 Jan 10; 24(2):145-55. PubMed ID: 9030225
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  • 18. Changes in p53 expression can modify cell shape of ras-transformed fibroblasts and epitheliocytes.
    Gloushankova N, Ossovskaya V, Vasiliev J, Chumakov P, Kopnin B.
    Oncogene; 1997 Dec 11; 15(24):2985-9. PubMed ID: 9416842
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  • 19. Ras-mediated suppression of TGFbetaRII expression in intestinal epithelial cells involves Raf-independent signaling.
    Bulus NM, Sheng HM, Sizemore N, Oldham SM, Barnett JV, Coffey RJ, Beauchamp DR, Barnard JA.
    Neoplasia; 2000 Dec 11; 2(4):357-64. PubMed ID: 11005570
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  • 20. Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells.
    James GL, Goldstein JL, Brown MS, Rawson TE, Somers TC, McDowell RS, Crowley CW, Lucas BK, Levinson AD, Marsters JC.
    Science; 1993 Jun 25; 260(5116):1937-42. PubMed ID: 8316834
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