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Journal Abstract Search

83 related items for PubMed ID: 8198608

  • 1. Purification and characterization of a novel metalloprotease from human brain with the ability to cleave substrates derived from the N-terminus of beta-amyloid protein.
    Schönlein C, Löffler J, Huber G.
    Biochem Biophys Res Commun; 1994 May 30; 201(1):45-53. PubMed ID: 8198608
    [Abstract] [Full Text] [Related]

  • 2. Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity.
    Yan R, Bienkowski MJ, Shuck ME, Miao H, Tory MC, Pauley AM, Brashier JR, Stratman NC, Mathews WR, Buhl AE, Carter DB, Tomasselli AG, Parodi LA, Heinrikson RL, Gurney ME.
    Nature; 1999 Dec 02; 402(6761):533-7. PubMed ID: 10591213
    [Abstract] [Full Text] [Related]

  • 3. The amyloid peptide precursor in Alzheimer's disease.
    Octave JN.
    Acta Neurol Belg; 1995 Dec 02; 95(4):197-209. PubMed ID: 8553793
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  • 4. A novel metalloprotease in rat brain cleaves the amyloid precursor protein of Alzheimer's disease generating amyloidogenic fragments.
    Mok SS, Evin G, Li QX, Smith AI, Beyreuther K, Masters CL, Small DH.
    Biochemistry; 1997 Jan 07; 36(1):156-63. PubMed ID: 8993329
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  • 5. BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein.
    Farzan M, Schnitzler CE, Vasilieva N, Leung D, Choe H.
    Proc Natl Acad Sci U S A; 2000 Aug 15; 97(17):9712-7. PubMed ID: 10931940
    [Abstract] [Full Text] [Related]

  • 6. Purification and cloning of amyloid precursor protein beta-secretase from human brain.
    Sinha S, Anderson JP, Barbour R, Basi GS, Caccavello R, Davis D, Doan M, Dovey HF, Frigon N, Hong J, Jacobson-Croak K, Jewett N, Keim P, Knops J, Lieberburg I, Power M, Tan H, Tatsuno G, Tung J, Schenk D, Seubert P, Suomensaari SM, Wang S, Walker D, Zhao J, McConlogue L, John V.
    Nature; 1999 Dec 02; 402(6761):537-40. PubMed ID: 10591214
    [Abstract] [Full Text] [Related]

  • 7. Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein.
    Nunan J, Williamson NA, Hill AF, Sernee MF, Masters CL, Small DH.
    J Neurosci Res; 2003 Nov 01; 74(3):378-85. PubMed ID: 14598314
    [Abstract] [Full Text] [Related]

  • 8. Genetic background regulates beta-amyloid precursor protein processing and beta-amyloid deposition in the mouse.
    Lehman EJ, Kulnane LS, Gao Y, Petriello MC, Pimpis KM, Younkin L, Dolios G, Wang R, Younkin SG, Lamb BT.
    Hum Mol Genet; 2003 Nov 15; 12(22):2949-56. PubMed ID: 14506131
    [Abstract] [Full Text] [Related]

  • 9. [Recent advances in Alzheimer's disease research--amyloid precursor protein trafficking, processing, and mutations in Alzheimer's disease linked genes].
    Fukatsu R, Tsuzuki K, Hayashi Y, Takamaru Y, Sasaki N, Yoshida T, Hatakeyama Y, Fuji N, Takahata N.
    Hokkaido Igaku Zasshi; 1997 Jan 15; 72(1):3-11. PubMed ID: 9086357
    [Abstract] [Full Text] [Related]

  • 10. P-glycoprotein efflux and other factors limit brain amyloid beta reduction by beta-site amyloid precursor protein-cleaving enzyme 1 inhibitors in mice.
    Meredith JE, Thompson LA, Toyn JH, Marcin L, Barten DM, Marcinkeviciene J, Kopcho L, Kim Y, Lin A, Guss V, Burton C, Iben L, Polson C, Cantone J, Ford M, Drexler D, Fiedler T, Lentz KA, Grace JE, Kolb J, Corsa J, Pierdomenico M, Jones K, Olson RE, Macor JE, Albright CF.
    J Pharmacol Exp Ther; 2008 Aug 15; 326(2):502-13. PubMed ID: 18499745
    [Abstract] [Full Text] [Related]

  • 11. Cloning and functional expression of a metalloendopeptidase from human brain with the ability to cleave a beta-APP substrate peptide.
    Thompson A, Huber G, Malherbe P.
    Biochem Biophys Res Commun; 1995 Aug 04; 213(1):66-73. PubMed ID: 7639763
    [Abstract] [Full Text] [Related]

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  • 13. Intracellular copper deficiency increases amyloid-beta secretion by diverse mechanisms.
    Cater MA, McInnes KT, Li QX, Volitakis I, La Fontaine S, Mercer JF, Bush AI.
    Biochem J; 2008 May 15; 412(1):141-52. PubMed ID: 18248325
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  • 17. Effects of peptides derived from BACE1 catalytic domain on APP processing.
    Yeon SW, Jeon YJ, Hwang EM, Kim TY.
    Peptides; 2007 Apr 15; 28(4):838-44. PubMed ID: 17293005
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  • 18. Inhibition of amyloid beta-peptide production by blockage of beta-secretase cleavage site of amyloid precursor protein.
    Na CH, Jeon SH, Zhang G, Olson GL, Chae CB.
    J Neurochem; 2007 Jun 15; 101(6):1583-95. PubMed ID: 17542811
    [Abstract] [Full Text] [Related]

  • 19. A metalloproteinase inhibitor domain in Alzheimer amyloid protein precursor.
    Miyazaki K, Hasegawa M, Funahashi K, Umeda M.
    Nature; 1993 Apr 29; 362(6423):839-41. PubMed ID: 8479521
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