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345 related items for PubMed ID: 8202083

  • 1. Requirement of the Pro-Cys-His-Arg sequence for O6-methylguanine-DNA methyltransferase activity revealed by saturation mutagenesis with negative and positive screening.
    Ihara K, Kawate H, Chueh LL, Hayakawa H, Sekiguchi M.
    Mol Gen Genet; 1994 May 25; 243(4):379-89. PubMed ID: 8202083
    [Abstract] [Full Text] [Related]

  • 2. Specific amino acid sequences required for O6-methylguanine-DNA methyltransferase activity: analyses of three residues at or near the methyl acceptor site.
    Chueh LL, Nakamura T, Nakatsu Y, Sakumi K, Hayakawa H, Sekiguchi M.
    Carcinogenesis; 1992 May 25; 13(5):837-43. PubMed ID: 1586996
    [Abstract] [Full Text] [Related]

  • 3. Site-directed mutation of the Escherichia coli ada gene: effects of substitution of methyl acceptor cysteine-321 by histidine in Ada protein.
    Tano K, Bhattacharyya D, Foote RS, Mural RJ, Mitra S.
    J Bacteriol; 1989 Mar 25; 171(3):1535-43. PubMed ID: 2493448
    [Abstract] [Full Text] [Related]

  • 4. Functional sites of the Ada regulatory protein of Escherichia coli. Analysis by amino acid substitutions.
    Takano K, Nakabeppu Y, Sekiguchi M.
    J Mol Biol; 1988 May 20; 201(2):261-71. PubMed ID: 3047400
    [Abstract] [Full Text] [Related]

  • 5. The role of the carboxyl-terminal tail in human O6-methylguanine DNA methyltransferase substrate specificity and temperature sensitivity.
    Morgan SE, Kelley MR, Pieper RO.
    J Biol Chem; 1993 Sep 15; 268(26):19802-9. PubMed ID: 8366118
    [Abstract] [Full Text] [Related]

  • 6. Site directed mutagenesis of two cysteine residues in the E. coli ogt O6-alkylguanine DNA alkyltransferase protein.
    Harris LC, Potter PM, Margison GP.
    Biochem Biophys Res Commun; 1992 Aug 31; 187(1):425-31. PubMed ID: 1520330
    [Abstract] [Full Text] [Related]

  • 7. Requirement for two conserved cysteine residues in the Ada protein of Escherichia coli for transactivation of the ada promoter.
    Taketomi A, Nakabeppu Y, Ihara K, Hart DJ, Furuichi M, Sekiguchi M.
    Mol Gen Genet; 1996 Mar 20; 250(5):523-32. PubMed ID: 8676855
    [Abstract] [Full Text] [Related]

  • 8. Purification to homogeneity and partial amino acid sequence of a fragment which includes the methyl acceptor site of the human DNA repair protein for O6-methylguanine.
    Major GN, Gardner EJ, Carne AF, Lawley PD.
    Nucleic Acids Res; 1990 Mar 25; 18(6):1351-9. PubMed ID: 2109306
    [Abstract] [Full Text] [Related]

  • 9. Specific recognition of O6-methylguanine in DNA by active site mutants of human O6-methylguanine-DNA methyltransferase.
    Hazra TK, Roy R, Biswas T, Grabowski DT, Pegg AE, Mitra S.
    Biochemistry; 1997 May 13; 36(19):5769-76. PubMed ID: 9153417
    [Abstract] [Full Text] [Related]

  • 10. Conformational change in human DNA repair enzyme O6-methylguanine-DNA methyltransferase upon alkylation of its active site by SN1 (indirect-acting) and SN2 (direct-acting) alkylating agents: breaking a "salt-link".
    Oh HK, Teo AK, Ali RB, Lim A, Ayi TC, Yarosh DB, Li BF.
    Biochemistry; 1996 Sep 24; 35(38):12259-66. PubMed ID: 8823159
    [Abstract] [Full Text] [Related]

  • 11. Cloning and expression of the Bacillus subtilis methyltransferase gene in Escherichia coli ada- cells.
    Kodama KI, Nakabeppu Y, Sekiguchi M.
    Mutat Res; 1989 Sep 24; 218(2):153-63. PubMed ID: 2505068
    [Abstract] [Full Text] [Related]

  • 12. Alteration of lysine 178 in the hinge region of the Escherichia coli ada protein interferes with activation of ada, but not alkA, transcription.
    Saget BM, Shevell DE, Walker GC.
    J Bacteriol; 1995 Mar 24; 177(5):1268-74. PubMed ID: 7868601
    [Abstract] [Full Text] [Related]

  • 13. A constitutive O6-methylguanine-DNA methyltransferase of Rhizobium meliloti.
    Kaufman A, Walker GC.
    Mutat Res; 1990 May 24; 235(3):165-9. PubMed ID: 2188120
    [Abstract] [Full Text] [Related]

  • 14. Mutagenic frequencies of site-specifically located O6-methylguanine in wild-type Escherichia coli and in a strain deficient in ada-methyltransferase.
    Rossi SC, Topal MD.
    J Bacteriol; 1991 Feb 24; 173(3):1201-7. PubMed ID: 1991716
    [Abstract] [Full Text] [Related]

  • 15. Crystal structure of a suicidal DNA repair protein: the Ada O6-methylguanine-DNA methyltransferase from E. coli.
    Moore MH, Gulbis JM, Dodson EJ, Demple B, Moody PC.
    EMBO J; 1994 Apr 01; 13(7):1495-501. PubMed ID: 8156986
    [Abstract] [Full Text] [Related]

  • 16. Characterization of cDNA encoding mouse DNA repair protein O6-methylguanine-DNA methyltransferase and high-level expression of the wild-type and mutant proteins in Escherichia coli.
    Shiota S, von Wronski MA, Tano K, Bigner DD, Brent TP, Mitra S.
    Biochemistry; 1992 Feb 25; 31(7):1897-903. PubMed ID: 1371399
    [Abstract] [Full Text] [Related]

  • 17. Repair of O6-benzylguanine by the Escherichia coli Ada and Ogt and the human O6-alkylguanine-DNA alkyltransferases.
    Goodtzova K, Kanugula S, Edara S, Pauly GT, Moschel RC, Pegg AE.
    J Biol Chem; 1997 Mar 28; 272(13):8332-9. PubMed ID: 9079656
    [Abstract] [Full Text] [Related]

  • 18. Structural and immunological comparison of indigenous human O6-methylguanine-DNA methyltransferase with that encoded by a cloned cDNA.
    von Wronski MA, Shiota S, Tano K, Mitra S, Bigner DD, Brent TP.
    J Biol Chem; 1991 Jan 15; 266(2):1064-70. PubMed ID: 1985934
    [Abstract] [Full Text] [Related]

  • 19. A single amino acid change in human O6-alkylguanine-DNA alkyltransferase decreasing sensitivity to inactivation by O6-benzylguanine.
    Crone TM, Pegg AE.
    Cancer Res; 1993 Oct 15; 53(20):4750-3. PubMed ID: 8402653
    [Abstract] [Full Text] [Related]

  • 20. Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine.
    Tano K, Shiota S, Collier J, Foote RS, Mitra S.
    Proc Natl Acad Sci U S A; 1990 Jan 15; 87(2):686-90. PubMed ID: 2405387
    [Abstract] [Full Text] [Related]

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