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Journal Abstract Search

326 related items for PubMed ID: 8206679

  • 1. Anti-Tac(Fab)-PE40, a recombinant double-chain immunotoxin which kills interleukin-2-receptor-bearing cells and induces complete remission in an in vivo tumor model.
    Kreitman RJ, Chang CN, Hudson DV, Queen C, Bailon P, Pastan I.
    Int J Cancer; 1994 Jun 15; 57(6):856-64. PubMed ID: 8206679
    [Abstract] [Full Text] [Related]

  • 2. Recombinant single-chain immunotoxins against T and B cell leukemias.
    Kreitman RJ, Pastan I.
    Leuk Lymphoma; 1994 Mar 15; 13(1-2):1-10. PubMed ID: 8025511
    [Abstract] [Full Text] [Related]

  • 3. Single-chain immunotoxin fusions between anti-Tac and Pseudomonas exotoxin: relative importance of the two toxin disulfide bonds.
    Kreitman RJ, Batra JK, Seetharam S, Chaudhary VK, FitzGerald DJ, Pastan I.
    Bioconjug Chem; 1993 Mar 15; 4(2):112-20. PubMed ID: 7873642
    [Abstract] [Full Text] [Related]

  • 4. Cytotoxic and antitumor activity of a recombinant immunotoxin composed of disulfide-stabilized anti-Tac Fv fragment and truncated Pseudomonas exotoxin.
    Reiter Y, Kreitman RJ, Brinkmann U, Pastan I.
    Int J Cancer; 1994 Jul 01; 58(1):142-9. PubMed ID: 8014011
    [Abstract] [Full Text] [Related]

  • 5. Recombinant immunotoxins containing anti-Tac(Fv) and derivatives of Pseudomonas exotoxin produce complete regression in mice of an interleukin-2 receptor-expressing human carcinoma.
    Kreitman RJ, Bailon P, Chaudhary VK, FitzGerald DJ, Pastan I.
    Blood; 1994 Jan 15; 83(2):426-34. PubMed ID: 8286741
    [Abstract] [Full Text] [Related]

  • 6. Cytotoxicity of recombinant Fab and Fv immunotoxins on adult T-cell leukemia lymph node and blood cells in the presence of soluble interleukin-2 receptor.
    Saito T, Kreitman RJ, Hanada S, Makino T, Utsunomiya A, Sumizawa T, Arima T, Chang CN, Hudson D, Pastan I.
    Cancer Res; 1994 Feb 15; 54(4):1059-64. PubMed ID: 8313362
    [Abstract] [Full Text] [Related]

  • 7. The recombinant immunotoxin anti-Tac(Fv)-Pseudomonas exotoxin 40 is cytotoxic toward peripheral blood malignant cells from patients with adult T-cell leukemia.
    Kreitman RJ, Chaudhary VK, Waldmann T, Willingham MC, FitzGerald DJ, Pastan I.
    Proc Natl Acad Sci U S A; 1990 Nov 15; 87(21):8291-5. PubMed ID: 2236041
    [Abstract] [Full Text] [Related]

  • 8. Accumulation of a recombinant immunotoxin in a tumor in vivo: fewer than 1000 molecules per cell are sufficient for complete responses.
    Kreitman RJ, Pastan I.
    Cancer Res; 1998 Mar 01; 58(5):968-75. PubMed ID: 9500458
    [Abstract] [Full Text] [Related]

  • 9. Anti-Tac(Fv)-PE40, a single chain antibody Pseudomonas fusion protein directed at interleukin 2 receptor bearing cells.
    Batra JK, FitzGerald D, Gately M, Chaudhary VK, Pastan I.
    J Biol Chem; 1990 Sep 05; 265(25):15198-202. PubMed ID: 2118522
    [Abstract] [Full Text] [Related]

  • 10. Recombinant anti-erbB2 immunotoxins containing Pseudomonas exotoxin.
    Batra JK, Kasprzyk PG, Bird RE, Pastan I, King CR.
    Proc Natl Acad Sci U S A; 1992 Jul 01; 89(13):5867-71. PubMed ID: 1352878
    [Abstract] [Full Text] [Related]

  • 11. Mik-beta 1(Fv)-PE40, a recombinant immunotoxin cytotoxic toward cells bearing the beta-chain of the IL-2 receptor.
    Kreitman RJ, Schneider WP, Queen C, Tsudo M, Fitzgerald DJ, Waldmann TA, Pastan I.
    J Immunol; 1992 Oct 15; 149(8):2810-5. PubMed ID: 1401913
    [Abstract] [Full Text] [Related]

  • 12. B3(Fab)-PE38M: a recombinant immunotoxin in which a mutant form of Pseudomonas exotoxin is fused to the Fab fragment of monoclonal antibody B3.
    Choe M, Webber KO, Pastan I.
    Cancer Res; 1994 Jul 01; 54(13):3460-7. PubMed ID: 8012967
    [Abstract] [Full Text] [Related]

  • 13. Single-chain immunotoxins directed at the human transferrin receptor containing Pseudomonas exotoxin A or diphtheria toxin: anti-TFR(Fv)-PE40 and DT388-anti-TFR(Fv).
    Batra JK, Fitzgerald DJ, Chaudhary VK, Pastan I.
    Mol Cell Biol; 1991 Apr 01; 11(4):2200-5. PubMed ID: 2005905
    [Abstract] [Full Text] [Related]

  • 14. TGF alpha-anti-Tac(Fv)-PE40: a bifunctional toxin cytotoxic for cells with EGF or IL2 receptors.
    Batra JK, Chaudhary VK, FitzGerald D, Pastan I.
    Biochem Biophys Res Commun; 1990 Aug 31; 171(1):1-6. PubMed ID: 2393383
    [Abstract] [Full Text] [Related]

  • 15. Characterization of B1(Fv)PE38 and B1(dsFv)PE38: single-chain and disulfide-stabilized Fv immunotoxins with increased activity that cause complete remissions of established human carcinoma xenografts in nude mice.
    Benhar I, Pastan I.
    Clin Cancer Res; 1995 Sep 31; 1(9):1023-9. PubMed ID: 9816075
    [Abstract] [Full Text] [Related]

  • 16. Activity of a single-chain immunotoxin that selectively kills lymphoma and other B-lineage cells expressing the CD40 antigen.
    Francisco JA, Gilliland LK, Stebbins MR, Norris NA, Ledbetter JA, Siegall CB.
    Cancer Res; 1995 Jul 15; 55(14):3099-104. PubMed ID: 7541711
    [Abstract] [Full Text] [Related]

  • 17. Antitumor activity of the single-chain immunotoxin BR96 sFv-PE40 against established breast and lung tumor xenografts.
    Friedman PN, Chace DF, Trail PA, Siegall CB.
    J Immunol; 1993 Apr 01; 150(7):3054-61. PubMed ID: 8454873
    [Abstract] [Full Text] [Related]

  • 18. Recombinant toxins containing the variable domains of the anti-Tac monoclonal antibody to the interleukin-2 receptor kill malignant cells from patients with chronic lymphocytic leukemia.
    Kreitman RJ, Chaudhary VK, Kozak RW, FitzGerald DJ, Waldman TA, Pastan I.
    Blood; 1992 Nov 01; 80(9):2344-52. PubMed ID: 1421405
    [Abstract] [Full Text] [Related]

  • 19. In vitro and in vivo characterization of BR96 sFv-PE40. A single-chain immunotoxin fusion protein that cures human breast carcinoma xenografts in athymic mice and rats.
    Siegall CB, Chace D, Mixan B, Garrigues U, Wan H, Paul L, Wolff E, Hellström I, Hellström KE.
    J Immunol; 1994 Mar 01; 152(5):2377-84. PubMed ID: 8133048
    [Abstract] [Full Text] [Related]

  • 20. Cytotoxic activities of recombinant immunotoxins composed of Pseudomonas toxin or diphtheria toxin toward lymphocytes from patients with adult T-cell leukemia.
    Kreitman RJ, Chaudhary VK, Waldmann TA, Hanchard B, Cranston B, FitzGerald DJ, Pastan I.
    Leukemia; 1993 Apr 01; 7(4):553-62. PubMed ID: 8464234
    [Abstract] [Full Text] [Related]

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