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122 related items for PubMed ID: 8213345

  • 1. In vitro pharmacology of BAY X1005, a new inhibitor of leukotriene synthesis.
    Fruchtmann R, Mohrs KH, Hatzelmann A, Raddatz S, Fugmann B, Junge B, Horstmann H, Müller-Peddinghaus R.
    Agents Actions; 1993 Mar; 38(3-4):188-95. PubMed ID: 8213345
    [Abstract] [Full Text] [Related]

  • 2. Ca2+ ionophore A23187-stimulated secretion of azurophil granules in human polymorphonuclear leukocytes is largely mediated by endogenously formed leukotriene B4.
    Hatzelmann A, Fruchtmann R, Mohrs KH, Raddatz S, Müller-Peddinghaus R.
    Biochem Pharmacol; 1994 Jul 05; 48(1):31-9. PubMed ID: 8043028
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  • 3. BAY X1005, a new selective inhibitor of leukotriene synthesis: pharmacology and pharmacokinetics.
    Müller-Peddinghaus R, Fruchtmann R, Ahr HJ, Beckermann B, Bühner K, Fugmann B, Junge B, Matzke M, Kohlsdorfer C, Raddatz S.
    J Lipid Mediat; 1993 Jul 05; 6(1-3):245-8. PubMed ID: 8395246
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  • 4. Mode of action of the new selective leukotriene synthesis inhibitor BAY X 1005 ((R)-2-[4-(quinolin-2-yl-methoxy)phenyl]-2-cyclopentyl acetic acid) and structurally related compounds.
    Hatzelmann A, Fruchtmann R, Mohrs KH, Raddatz S, Müller-Peddinghaus R.
    Biochem Pharmacol; 1993 Jan 07; 45(1):101-11. PubMed ID: 8381000
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  • 5. (R)-2-[4-(quinolin-2-yl-methoxy)phenyl]-2-cyclopentyl] acetic acid (BAY x1005), a potent leukotriene synthesis inhibitor: effects on anti-IgE challenge in human airways.
    Gorenne I, Labat C, Gascard JP, Norel X, Müller-Peddinghaus R, Mohrs KH, Taylor WA, Gardiner PJ, Brink C.
    J Pharmacol Exp Ther; 1994 Feb 07; 268(2):868-72. PubMed ID: 8114000
    [Abstract] [Full Text] [Related]

  • 6. BAY X1005, a new inhibitor of leukotriene synthesis: in vivo inflammation pharmacology and pharmacokinetics.
    Müller-Peddinghaus R, Kohlsdorfer C, Theisen-Popp P, Fruchtmann R, Perzborn E, Beckermann B, Bühner K, Ahr HJ, Mohrs KH.
    J Pharmacol Exp Ther; 1993 Oct 07; 267(1):51-7. PubMed ID: 8229782
    [Abstract] [Full Text] [Related]

  • 7. Pharmacology of the 5-lipoxygenase inhibitors BAY Y 1015 and BAY X 1005 in the horse.
    Cunningham FM, Andrews M, Landoni MF, Lees P.
    J Vet Pharmacol Ther; 1997 Aug 07; 20(4):296-307. PubMed ID: 9280370
    [Abstract] [Full Text] [Related]

  • 8. Pharmacological modulation of human platelet leukotriene C4-synthase.
    Sala A, Folco G, Henson PM, Murphy RC.
    Biochem Pharmacol; 1997 Mar 21; 53(6):905-8. PubMed ID: 9113110
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of antigen-induced contraction of guinea-pig airways by a leukotriene synthesis inhibitor, BAY x1005.
    Gardiner PJ, Cuthbert NJ, Francis HP, Fitzgerald MF, Thompson AM, Carpenter TG, Patel UP, Newton BB, Mohrs K, Müller-Peddinghaus R.
    Eur J Pharmacol; 1994 Jun 02; 258(1-2):95-102. PubMed ID: 7925604
    [Abstract] [Full Text] [Related]

  • 10. Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models.
    Carty TJ, Sweeney FJ, Griffiths RJ, Eskra JD, Ernest MJ, Pillar JS, Cheng JD, Loose LD, Joseph PA, Pazoles PP, Moore PF, Nagahisa A, Murase S, Kadin SB.
    Inflamm Res; 1997 May 02; 46(5):168-79. PubMed ID: 9197987
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  • 12. Ionophore A23187-induced leukotriene biosynthesis in equine granulocytes-neutrophils, but not eosinophils require exogenous arachidonic acid.
    Lindberg A, Tornhamre S, Mugnai S, Lindgren J.
    Biochim Biophys Acta; 1998 Mar 30; 1391(2):247-55. PubMed ID: 9555040
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  • 18. Methoxytetrahydropyrans. A new series of selective and orally potent 5-lipoxygenase inhibitors.
    Crawley GC, Dowell RI, Edwards PN, Foster SJ, McMillan RM, Walker ER, Waterson D, Bird TG, Bruneau P, Giroaeau JM.
    J Med Chem; 1992 Jul 10; 35(14):2600-9. PubMed ID: 1321908
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  • 19. Nedocromil sodium inhibits the A23187- and opsonized zymosan-induced leukotriene formation by human eosinophils but not by human neutrophils.
    Bruijnzeel PL, Hamelink ML, Kok PT, Kreukniet J.
    Br J Pharmacol; 1989 Mar 10; 96(3):631-6. PubMed ID: 2541846
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  • 20. In vivo sex differences in leukotriene biosynthesis in zymosan-induced peritonitis.
    Rossi A, Pergola C, Pace S, Rådmark O, Werz O, Sautebin L.
    Pharmacol Res; 2014 Sep 10; 87():1-7. PubMed ID: 24892983
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