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Journal Abstract Search

808 related items for PubMed ID: 8214760

  • 1. Identification of cytochrome P450 2E1 as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane, and methoxyflurane.
    Kharasch ED, Thummel KE.
    Anesthesiology; 1993 Oct; 79(4):795-807. PubMed ID: 8214760
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  • 3. Human liver microsomal enflurane defluorination catalyzed by cytochrome P-450 2E1.
    Thummel KE, Kharasch ED, Podoll T, Kunze K.
    Drug Metab Dispos; 1993 Oct; 21(2):350-7. PubMed ID: 8097708
    [Abstract] [Full Text] [Related]

  • 4. Metabolism by rat hepatic microsomes of fluorinated ether anesthetics following ethanol consumption.
    Rice SA, Dooley JR, Mazze RI.
    Anesthesiology; 1983 Mar; 58(3):237-41. PubMed ID: 6829959
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  • 5. Biotransformation of sevoflurane.
    Kharasch ED.
    Anesth Analg; 1995 Dec; 81(6 Suppl):S27-38. PubMed ID: 7486145
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  • 6. Lauric acid as a model substrate for the simultaneous determination of cytochrome P450 2E1 and 4A in hepatic microsomes.
    Clarke SE, Baldwin SJ, Bloomer JC, Ayrton AD, Sozio RS, Chenery RJ.
    Chem Res Toxicol; 1994 Dec; 7(6):836-42. PubMed ID: 7696540
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  • 8. P450-dependent and nonenzymatic human liver microsomal defluorination of fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A), a sevoflurane degradation product.
    Kharasch ED, Hankins DC.
    Drug Metab Dispos; 1996 Jun; 24(6):649-54. PubMed ID: 8781780
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  • 9. Stereoselective metabolism of enflurane by human liver cytochrome P450 2E1.
    Garton KJ, Yuen P, Meinwald J, Thummel KE, Kharasch ED.
    Drug Metab Dispos; 1995 Dec; 23(12):1426-30. PubMed ID: 8689955
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  • 11. Effect of phenytoin (DPH) treatment on methoxyflurane metabolism in rats.
    Caughey GH, Rice SA, Kosek JC, Mazze RI.
    J Pharmacol Exp Ther; 1979 Aug; 210(2):180-5. PubMed ID: 458627
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  • 13. Effect of streptozotocin-induced diabetes in the rat on the metabolism of fluorinated volatile anesthetics.
    Pantuck EJ, Pantuck CB, Conney AH.
    Anesthesiology; 1987 Jan; 66(1):24-8. PubMed ID: 3541691
    [Abstract] [Full Text] [Related]

  • 14. Clinical enflurane metabolism by cytochrome P450 2E1.
    Kharasch ED, Thummel KE, Mautz D, Bosse S.
    Clin Pharmacol Ther; 1994 Apr; 55(4):434-40. PubMed ID: 8162670
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  • 15. Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4.
    Spracklin DK, Thummel KE, Kharasch ED.
    Drug Metab Dispos; 1996 Sep; 24(9):976-83. PubMed ID: 8886607
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  • 16. Ethanol-inducible cytochrome P450 in rabbits metabolizes enflurane.
    Hoffman J, Konopka K, Buckhorn C, Koop DR, Waskell L.
    Br J Anaesth; 1989 Jul; 63(1):103-8. PubMed ID: 2765333
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  • 17. Enflurane, isoflurane, and methoxyflurane metabolism in rat hepatic microsomes from ethanol-treated animals.
    Van Dyke RA.
    Anesthesiology; 1983 Mar; 58(3):221-4. PubMed ID: 6829956
    [Abstract] [Full Text] [Related]

  • 18. Cytochrome P450 2E1 is the principal catalyst of human oxidative halothane metabolism in vitro.
    Spracklin DK, Hankins DC, Fisher JM, Thummel KE, Kharasch ED.
    J Pharmacol Exp Ther; 1997 Apr; 281(1):400-11. PubMed ID: 9103523
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  • 19. Kinetic analysis of the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by heterologously expressed human P450 enzymes and the effect of P450-specific chemical inhibitors on this activation in human liver microsomes.
    Patten CJ, Smith TJ, Murphy SE, Wang MH, Lee J, Tynes RE, Koch P, Yang CS.
    Arch Biochem Biophys; 1996 Sep 01; 333(1):127-38. PubMed ID: 8806763
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  • 20. Metabolism of synthane: comparison with in vivo and in vitro defluorination of other halogenated hydrocarbon anaesthetics.
    Mazze RI, Beppu WJ, Hitt BA.
    Br J Anaesth; 1979 Sep 01; 51(9):839-44. PubMed ID: 508489
    [Abstract] [Full Text] [Related]

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