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Journal Abstract Search

185 related items for PubMed ID: 8215408

  • 1. 6-substituted 3,4-benzocoumarins: a new structural class of inducers and inhibitors of CYP1A1-dependent activity.
    Liu H, Santostefano M, Lu Y, Safe S.
    Arch Biochem Biophys; 1993 Oct; 306(1):223-31. PubMed ID: 8215408
    [Abstract] [Full Text] [Related]

  • 2. 2-Phenylphenanthridinone and related compounds: aryl hydrocarbon receptor agonists and suicide inactivators of P4501A1.
    Liu H, Santostefano M, Safe S.
    Arch Biochem Biophys; 1994 Sep; 313(2):206-14. PubMed ID: 8080264
    [Abstract] [Full Text] [Related]

  • 3. Mechanism of action of aryl hydrocarbon receptor antagonists: inhibition of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 gene expression.
    Merchant M, Morrison V, Santostefano M, Safe S.
    Arch Biochem Biophys; 1992 Nov 01; 298(2):389-94. PubMed ID: 1329656
    [Abstract] [Full Text] [Related]

  • 4. Identification of 3'-methoxy-4'-nitroflavone as a pure aryl hydrocarbon (Ah) receptor antagonist and evidence for more than one form of the nuclear Ah receptor in MCF-7 human breast cancer cells.
    Lu YF, Santostefano M, Cunningham BD, Threadgill MD, Safe S.
    Arch Biochem Biophys; 1995 Jan 10; 316(1):470-7. PubMed ID: 7840652
    [Abstract] [Full Text] [Related]

  • 5. 6-substituted-1,3,8-trichlorodibenzofurans as 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonists in the rat: structure activity relationships.
    Astroff B, Safe S.
    Toxicology; 1989 Dec 15; 59(3):285-96. PubMed ID: 2631297
    [Abstract] [Full Text] [Related]

  • 6. 2,3,7,8-Tetrachlorodibenzo-p-dioxin versus 3-methylcholanthrene: comparative studies of Ah receptor binding, transformation, and induction of CYP1A1.
    Riddick DS, Huang Y, Harper PA, Okey AB.
    J Biol Chem; 1994 Apr 22; 269(16):12118-28. PubMed ID: 8163516
    [Abstract] [Full Text] [Related]

  • 7. Uroporphyrin accumulation associated with cytochrome P4501A induction in fish hepatoma cells exposed to aryl hydrocarbon receptor agonists, including 2,3,7,8-tetrachlorodibenzo-p-dioxin and planar chlorobiphenyls.
    Hahn ME, Chandran K.
    Arch Biochem Biophys; 1996 May 15; 329(2):163-74. PubMed ID: 8638948
    [Abstract] [Full Text] [Related]

  • 8. Mechanism of action of 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonists: characterization of 6-[125I]methyl-8-iodo-1,3-dichlorodibenzofuran-Ah receptor complexes.
    Piskorska-Pliszczynska J, Astroff B, Zacharewski T, Harris M, Rosengren R, Morrison V, Safe L, Safe S.
    Arch Biochem Biophys; 1991 Jan 15; 284(1):193-200. PubMed ID: 1846513
    [Abstract] [Full Text] [Related]

  • 9. 6-Methyl-1,3,8-trichlorodibenzofuran as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: inhibition of the induction of rat cytochrome P-450 isozymes and related monooxygenase activities.
    Astroff B, Zacharewski T, Safe S, Arlotto MP, Parkinson A, Thomas P, Levin W.
    Mol Pharmacol; 1988 Feb 15; 33(2):231-6. PubMed ID: 2828916
    [Abstract] [Full Text] [Related]

  • 10. Partial antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated induction of aryl hydrocarbon hydroxylase by 6-methyl-1,3,8-trichlorodibenzofuran: mechanistic studies.
    Harris M, Zacharewski T, Astroff B, Safe S.
    Mol Pharmacol; 1989 May 15; 35(5):729-35. PubMed ID: 2542761
    [Abstract] [Full Text] [Related]

  • 11. Potentiation of CYP1A1 gene expression in MCF-7 human breast cancer cells cotreated with 2,3,7,8-tetrachlorodibenzo-p-dioxin and 12-O-tetradecanoylphorbol-13-acetate.
    Moore M, Narasimhan TR, Steinberg MA, Wang X, Safe S.
    Arch Biochem Biophys; 1993 Sep 15; 305(2):483-8. PubMed ID: 8396892
    [Abstract] [Full Text] [Related]

  • 12. Induction of cytochrome P450-dependent monooxygenase activities in rat hepatoma H-4-IIE cells in culture by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds: mechanistic studies using radiolabeled congeners.
    Zacharewski T, Harris M, Safe S.
    Arch Biochem Biophys; 1989 Aug 01; 272(2):344-55. PubMed ID: 2546497
    [Abstract] [Full Text] [Related]

  • 13. Ah receptor in mice genetically "nonresponsive" for cytochrome P4501A1 induction: cytosolic Ah receptor, transformation to the nuclear binding state, and induction of aryl hydrocarbon hydroxylase by halogenated and nonhalogenated aromatic hydrocarbons in embryonic tissues and cells.
    Harper PA, Golas CL, Okey AB.
    Mol Pharmacol; 1991 Nov 01; 40(5):818-26. PubMed ID: 1658612
    [Abstract] [Full Text] [Related]

  • 14. The mechanism of action of alpha-naphthoflavone as an inhibitor of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 gene expression.
    Merchant M, Arellano L, Safe S.
    Arch Biochem Biophys; 1990 Aug 15; 281(1):84-9. PubMed ID: 2166479
    [Abstract] [Full Text] [Related]

  • 15. Substituted flavones as aryl hydrocarbon (Ah) receptor agonists and antagonists.
    Lu YF, Santostefano M, Cunningham BD, Threadgill MD, Safe S.
    Biochem Pharmacol; 1996 Apr 26; 51(8):1077-87. PubMed ID: 8866830
    [Abstract] [Full Text] [Related]

  • 16. Mechanism of action of alpha-naphthoflavone as an Ah receptor antagonist in MCF-7 human breast cancer cells.
    Merchant M, Krishnan V, Safe S.
    Toxicol Appl Pharmacol; 1993 Jun 26; 120(2):179-85. PubMed ID: 8390116
    [Abstract] [Full Text] [Related]

  • 17. alpha-Naphthoflavone antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced murine lymphocyte ethoxyresorufin-O-deethylase activity and immunosuppression.
    Blank JA, Tucker AN, Sweatlock J, Gasiewicz TA, Luster MI.
    Mol Pharmacol; 1987 Jul 26; 32(1):169-72. PubMed ID: 3037301
    [Abstract] [Full Text] [Related]

  • 18. Characterization of the Ah receptor and aryl hydrocarbon hydroxylase induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin and benz(a)anthracene in the human A431 squamous cell carcinoma line.
    Harper PA, Golas CL, Okey AB.
    Cancer Res; 1988 May 01; 48(9):2388-95. PubMed ID: 2833345
    [Abstract] [Full Text] [Related]

  • 19. Effects of substituents on the cytosolic receptor-binding avidities and aryl hydrocarbon hydroxylase induction potencies of 7-substituted 2,3-dichlorodibenzo-p-dioxins. A quantitative structure-activity relationship analysis.
    Denomme MA, Homonoko K, Fujita T, Sawyer T, Safe S.
    Mol Pharmacol; 1985 Jun 01; 27(6):656-61. PubMed ID: 2987660
    [Abstract] [Full Text] [Related]

  • 20. Ah receptor mediating induction of cytochrome P450IA1 in a novel continuous human liver cell line (Mz-Hep-1). Detection by binding with [3H]2,3,7,8-tetrachlorodibenzo-p-dioxin and relationship to the activity of aryl hydrocarbon hydroxylase.
    Roberts EA, Johnson KC, Dippold WG.
    Biochem Pharmacol; 1991 Jul 15; 42(3):521-8. PubMed ID: 1650214
    [Abstract] [Full Text] [Related]

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