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Journal Abstract Search

103 related items for PubMed ID: 8216452

  • 1. Synthesis and biological activity of a series of aryl tropanyl esters and amides chemically related to 1H-indole-3-carboxylic acid endo 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester. Development of a 5-HT4 agonist endowed with potent antinociceptive activity.
    Romanelli MN, Ghelardini C, Dei S, Matucci R, Mori F, Scapecchi S, Teodori E, Bartolini A, Galli A, Giotti A.
    Arzneimittelforschung; 1993 Aug; 43(8):913-8. PubMed ID: 8216452
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  • 2. Roles of serotonin receptor subtypes for the antinociception of 5-HT in the spinal cord of rats.
    Jeong CY, Choi JI, Yoon MH.
    Eur J Pharmacol; 2004 Oct 19; 502(3):205-11. PubMed ID: 15476746
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  • 3. 2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxamides with selective affinity for the 5-HT(4) receptor: synthesis and structure-affinity and structure-activity relationships of a new series of partial agonist and antagonist derivatives.
    Tapia I, Alonso-Cires L, López-Tudanca PL, Mosquera R, Labeaga L, Innerárity A, Orjales A.
    J Med Chem; 1999 Jul 29; 42(15):2870-80. PubMed ID: 10425096
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  • 4. 2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists.
    Mattsson C, Sonesson C, Sandahl A, Greiner HE, Gassen M, Plaschke J, Leibrock J, Böttcher H.
    Bioorg Med Chem Lett; 2005 Oct 01; 15(19):4230-4. PubMed ID: 16055331
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  • 5. Further structure-activity relationships in the series of tropanyl esters endowed with potent antinociceptive activity.
    Scapecchi S, Giorgi A, Bellucci C, Dei S, Ghelardini C, Manetti D, Romanelli MN, Teodori E.
    Farmaco; 1998 Dec 30; 53(12):764-72. PubMed ID: 10230057
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  • 6. Synthesis and 5-HT3 receptor affinity of new quinolinecarboxylic acid derivatives.
    Orjales A, Alonso-Cires L, López-Tudanca PL, Tapia I, Labeaga L, Mosquera R.
    Drug Des Discov; 2000 Dec 30; 16(4):271-9. PubMed ID: 10807033
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  • 8. Antinociceptive profile of 3-alpha-tropanyl 2-(4-Cl-phenoxy)butyrate (SM-21) [corrected]: a novel analgesic with a presynaptic cholinergic mechanism of action.
    Ghelardini C, Galeotti N, Gualtieri F, Bellucci C, Manetti D, Giotti A, Malmberg-Aiello P, Galli A, Bartolini A.
    J Pharmacol Exp Ther; 1997 Jul 30; 282(1):430-9. PubMed ID: 9223584
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  • 13. Synthesis and serotonergic activity of 3-[2-(pyrrolidin-1-yl)ethyl]indoles: potent agonists for the h5-HT1D receptor with high selectivity over the h5-HT1B receptor.
    Sternfeld F, Guiblin AR, Jelley RA, Matassa VG, Reeve AJ, Hunt PA, Beer MS, Heald A, Stanton JA, Sohal B, Watt AP, Street LJ.
    J Med Chem; 1999 Feb 25; 42(4):677-90. PubMed ID: 10052975
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  • 14. The selective 5-HT1B receptor inverse agonist 1'-methyl-5-[[2'-methyl-4'-(5-methyl-1,2, 4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-f]indole-3,4'-piperidine] (SB-224289) potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo.
    Gaster LM, Blaney FE, Davies S, Duckworth DM, Ham P, Jenkins S, Jennings AJ, Joiner GF, King FD, Mulholland KR, Wyman PA, Hagan JJ, Hatcher J, Jones BJ, Middlemiss DN, Price GW, Riley G, Roberts C, Routledge C, Selkirk J, Slade PD.
    J Med Chem; 1998 Apr 09; 41(8):1218-35. PubMed ID: 9548813
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  • 19. Synthesis and structure-activity relationships of potent and orally active 5-HT4 receptor antagonists: indazole and benzimidazolone derivatives.
    Schaus JM, Thompson DC, Bloomquist WE, Susemichel AD, Calligaro DO, Cohen ML.
    J Med Chem; 1998 May 21; 41(11):1943-55. PubMed ID: 9599243
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