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Journal Abstract Search

176 related items for PubMed ID: 8226741

  • 1. Mechanisms of camptothecin resistance in yeast DNA topoisomerase I mutants.
    Knab AM, Fertala J, Bjornsti MA.
    J Biol Chem; 1993 Oct 25; 268(30):22322-30. PubMed ID: 8226741
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  • 2. A camptothecin-resistant DNA topoisomerase I mutant exhibits altered sensitivities to other DNA topoisomerase poisons.
    Knab AM, Fertala J, Bjornsti MA.
    J Biol Chem; 1995 Mar 17; 270(11):6141-8. PubMed ID: 7890748
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  • 3. Camptothecin sensitivity is mediated by the pleiotropic drug resistance network in yeast.
    Reid RJ, Kauh EA, Bjornsti MA.
    J Biol Chem; 1997 May 02; 272(18):12091-9. PubMed ID: 9115278
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  • 4. Yeast Saccharomyces cerevisiae as a model system to study the cytotoxic activity of the antitumor drug camptothecin.
    Bjornsti MA, Knab AM, Benedetti P.
    Cancer Chemother Pharmacol; 1994 May 02; 34 Suppl():S1-5. PubMed ID: 8070016
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  • 5. Increased camptothecin toxicity induced in mammalian cells expressing Saccharomyces cerevisiae DNA topoisomerase I.
    Hann C, Evans DL, Fertala J, Benedetti P, Bjornsti MA, Hall DJ.
    J Biol Chem; 1998 Apr 03; 273(14):8425-33. PubMed ID: 9525954
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  • 6. Camptothecin resistance from a single mutation changing glycine 363 of human DNA topoisomerase I to cysteine.
    Benedetti P, Fiorani P, Capuani L, Wang JC.
    Cancer Res; 1993 Sep 15; 53(18):4343-8. PubMed ID: 8395982
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  • 7. An engineered mutant of vaccinia virus DNA topoisomerase I is sensitive to the anti-cancer drug camptothecin.
    Gupta M, Zhu CX, Tse-Dinh YC.
    J Biol Chem; 1992 Dec 05; 267(34):24177-80. PubMed ID: 1332948
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  • 8. Peptide sequencing and site-directed mutagenesis identify tyrosine-727 as the active site tyrosine of Saccharomyces cerevisiae DNA topoisomerase I.
    Lynn RM, Bjornsti MA, Caron PR, Wang JC.
    Proc Natl Acad Sci U S A; 1989 May 05; 86(10):3559-63. PubMed ID: 2542938
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  • 14. Covalent and noncovalent DNA binding by mutants of vaccinia DNA topoisomerase I.
    Morham SG, Shuman S.
    J Biol Chem; 1992 Aug 05; 267(22):15984-92. PubMed ID: 1322412
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  • 15. DNA topoisomerase I domain interactions impact enzyme activity and sensitivity to camptothecin.
    Wright CM, van der Merwe M, DeBrot AH, Bjornsti MA.
    J Biol Chem; 2015 May 08; 290(19):12068-78. PubMed ID: 25795777
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  • 16. Expression of human DNA topoisomerase I in yeast cells lacking yeast DNA topoisomerase I: restoration of sensitivity of the cells to the antitumor drug camptothecin.
    Bjornsti MA, Benedetti P, Viglianti GA, Wang JC.
    Cancer Res; 1989 Nov 15; 49(22):6318-23. PubMed ID: 2553253
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  • 17. Domain interactions affecting human DNA topoisomerase I catalysis and camptothecin sensitivity.
    Fiorani P, Amatruda JF, Silvestri A, Butler RH, Bjornsti MA, Benedetti P.
    Mol Pharmacol; 1999 Dec 15; 56(6):1105-15. PubMed ID: 10570037
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  • 20. Locking the DNA topoisomerase I protein clamp inhibits DNA rotation and induces cell lethality.
    Woo MH, Losasso C, Guo H, Pattarello L, Benedetti P, Bjornsti MA.
    Proc Natl Acad Sci U S A; 2003 Nov 25; 100(24):13767-72. PubMed ID: 14585933
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