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Journal Abstract Search


160 related items for PubMed ID: 8230119

  • 1. 5-HT3 receptor antagonists. 3. Quinoline derivatives which may be effective in the therapy of irritable bowel syndrome.
    Kishibayashi N, Miwa Y, Hayashi H, Ishii A, Ichikawa S, Nonaka H, Yokoyama T, Suzuki F.
    J Med Chem; 1993 Oct 29; 36(22):3286-92. PubMed ID: 8230119
    [Abstract] [Full Text] [Related]

  • 2. 5-HT3 receptor antagonists. 2. 4-Hydroxy-3-quinolinecarboxylic acid derivatives.
    Hayashi H, Miwa Y, Ichikawa S, Yoda N, Miki I, Ishii A, Kono M, Yasuzawa T, Suzuki F.
    J Med Chem; 1993 Mar 05; 36(5):617-26. PubMed ID: 8496941
    [Abstract] [Full Text] [Related]

  • 3. Pharmacological properties of KF18259, a novel 5-HT3-receptor antagonist, in rats: inhibition of the distal colonic function.
    Kishibayashi N, Ichikawa S, Yokoyama T, Ishii A, Karasawa A.
    Jpn J Pharmacol; 1993 Dec 05; 63(4):495-502. PubMed ID: 8121082
    [Abstract] [Full Text] [Related]

  • 4. Comparison of the effects of trimebutine and YM114 (KAE-393), a novel 5-HT3 receptor antagonist, on stress-induced defecation.
    Miyata K, Ito H, Yamano M, Hidaka K, Kamato T, Nishida A, Yuki H.
    Eur J Pharmacol; 1993 Dec 07; 250(2):303-10. PubMed ID: 8112388
    [Abstract] [Full Text] [Related]

  • 5. Effect of FK1052, a potent 5-hydroxytryptamine3 and 5-hydroxytryptamine4 receptor dual antagonist, on colonic function in vivo.
    Kadowaki M, Nagakura Y, Tomoi M, Mori J, Kohsaka M.
    J Pharmacol Exp Ther; 1993 Jul 07; 266(1):74-80. PubMed ID: 8331576
    [Abstract] [Full Text] [Related]

  • 6. 5-HT3 receptor antagonists. 1. New quinoline derivatives.
    Hayashi H, Miwa Y, Miki I, Ichikawa S, Yoda N, Ishii A, Kono M, Suzuki F.
    J Med Chem; 1992 Dec 25; 35(26):4893-902. PubMed ID: 1479589
    [Abstract] [Full Text] [Related]

  • 7. Effect of ramosetron on conditioned emotional stress-induced colonic dysfunction as a model of irritable bowel syndrome in rats.
    Funatsu T, Takeuchi A, Hirata T, Keto Y, Akuzawa S, Sasamata M.
    Eur J Pharmacol; 2007 Nov 14; 573(1-3):190-5. PubMed ID: 17658508
    [Abstract] [Full Text] [Related]

  • 8. The function of 5-HT3 receptors on colonic transit in rats.
    Haga K, Asano K, Fukuda T, Kobayakawa T.
    Obes Res; 1995 Dec 14; 3 Suppl 5():801S-810S. PubMed ID: 8653566
    [Abstract] [Full Text] [Related]

  • 9. Effect of YNS-15P, a new alpha-2 adrenoceptor antagonist, on stress-stimulated colonic propulsion in rats.
    Yamamoto O, Niida H, Tajima K, Shirouchi Y, Kyotani Y, Ueda F, Kise M, Kimura K.
    J Pharmacol Exp Ther; 1998 Nov 14; 287(2):691-6. PubMed ID: 9808698
    [Abstract] [Full Text] [Related]

  • 10. Effect of GK-128 [2-[(2-methylimidazol-1-yl)methyl]-benzo[f]thiochromen-1-one monohydrochloride hemihydrate], a selective 5-hydroxytryptamine3 receptor antagonist, on colonic function in rats.
    Ito C, Isobe Y, Kawamura R, Kiuchi Y, Tsuchida K, Higuchi S.
    J Pharmacol Exp Ther; 1997 Jan 14; 280(1):67-72. PubMed ID: 8996183
    [Abstract] [Full Text] [Related]

  • 11. Role of the serotonin3 receptor in stress-induced defecation.
    Miyata K, Kamato T, Nishida A, Ito H, Yuki H, Yamano M, Tsutsumi R, Katsuyama Y, Honda K.
    J Pharmacol Exp Ther; 1992 Apr 14; 261(1):297-303. PubMed ID: 1560375
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of stress-stimulated colonic propulsion by alpha 2-adrenoceptor antagonists in rats.
    Yamamoto O, Niida H, Tajima K, Shirouchi Y, Masui Y, Ueda F, Kise M, Kimura K.
    Neurogastroenterol Motil; 1998 Dec 14; 10(6):523-32. PubMed ID: 10050258
    [Abstract] [Full Text] [Related]

  • 13. Characteristics of inhibitory effects of serotonin (5-HT)3-receptor antagonists, YM060 and YM114 (KAE-393), on the von Bezold-Jarisch reflex induced by 2-Methyl-5-HT, veratridine and electrical stimulation of vagus nerves in anesthetized rats.
    Yamano M, Ito H, Kamato T, Miyata K.
    Jpn J Pharmacol; 1995 Dec 14; 69(4):351-6. PubMed ID: 8786638
    [Abstract] [Full Text] [Related]

  • 14. Serotonin (5-HT)3 receptor blocking activities of YM060, a novel 4,5,6,7-tetrahydrobenzimidazole derivative, and its enantiomer in anesthetized rats.
    Miyata K, Kamato T, Yamano M, Nishida A, Ito H, Katsuyama Y, Yuki H, Tsutsumi R, Ohta M, Takeda M.
    J Pharmacol Exp Ther; 1991 Nov 14; 259(2):815-9. PubMed ID: 1941629
    [Abstract] [Full Text] [Related]

  • 15. Effects of YM905, a novel muscarinic M3-receptor antagonist, on experimental models of bowel dysfunction in vivo.
    Kobayashi S, Ikeda K, Suzuki M, Yamada T, Miyata K.
    Jpn J Pharmacol; 2001 Jul 14; 86(3):281-8. PubMed ID: 11488427
    [Abstract] [Full Text] [Related]

  • 16. Evaluation of the pharmacological profile of ramosetron, a novel therapeutic agent for irritable bowel syndrome.
    Hirata T, Keto Y, Funatsu T, Akuzawa S, Sasamata M.
    J Pharmacol Sci; 2007 Jul 14; 104(3):263-73. PubMed ID: 17652911
    [Abstract] [Full Text] [Related]

  • 17. Benzoxazines. II. Synthesis, conformational analysis, and structure--activity relationships of 3,4-dihydro-2H-1,4-benzoxazine-8-carboxamide derivatives as potent and long-acting serotonin-3 (5-HT3) receptor antagonists.
    Kuroita T, Marubayashi N, Sano M, Kanzaki K, Inaba K, Kawakita T.
    Chem Pharm Bull (Tokyo); 1996 Nov 14; 44(11):2051-60. PubMed ID: 8945770
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and structure-activity relationships of 2,3-dihydrobenzofuran-7-carboxamide derivatives as potent serotonin-3 (5-HT3) receptor antagonists.
    Kuroita T, Yasumoto M, Inaba K, Sakamori M, Takehara S, Kawakita T.
    Chem Pharm Bull (Tokyo); 1994 Jan 14; 42(1):95-100. PubMed ID: 8124772
    [Abstract] [Full Text] [Related]

  • 19. Novel 5-hydroxytryptamine (5-HT3) receptor antagonists. III. Pharmacological evaluations and molecular modeling studies of optically active 4,5,6,7-tetrahydro-1H-benzimidazole derivatives.
    Ohta M, Suzuki T, Furuya T, Kurihara H, Tokunaga T, Miyata K, Yanagisawa I.
    Chem Pharm Bull (Tokyo); 1996 Sep 14; 44(9):1707-16. PubMed ID: 8855365
    [Abstract] [Full Text] [Related]

  • 20. Species difference in the 5-hydroxytryptamine3 receptor associated with the von Bezold-Jarisch reflex.
    Yamano M, Ito H, Kamato T, Miyata K.
    Arch Int Pharmacodyn Ther; 1995 Sep 14; 330(2):177-89. PubMed ID: 8861711
    [Abstract] [Full Text] [Related]


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