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Journal Abstract Search


147 related items for PubMed ID: 8230131

  • 1. Orally active central dopamine and serotonin receptor ligands: 5-, 6-, 7-, and 8-[[trifluoromethyl)sulfonyl]oxy]-2-(di-n-propylamino)tetralins and the formation of active metabolites in vivo.
    Sonesson C, Boije M, Svensson K, Ekman A, Carlsson A, Romero AG, Martin IJ, Duncan JN, King LJ, Wikström H.
    J Med Chem; 1993 Oct 29; 36(22):3409-16. PubMed ID: 8230131
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  • 5. Oral cavity absorption of (R)-8-hydroxy-2-(di-n-propylamino)tetralin and (S)-8-acetyl-2-(di-n-propylamino)tetralin in the rat.
    Yu H, Liu Y, Hacksell U, Lewander T.
    J Pharm Pharmacol; 1996 Jan 29; 48(1):41-5. PubMed ID: 8722493
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  • 8. 8-Hydroxy-2-(alkylamino)tetralins and related compounds as central 5-hydroxytryptamine receptor agonists.
    Arvidsson LE, Hacksell U, Johansson AM, Nilsson JL, Lindberg P, Sanchez D, Wikström H, Svensson K, Hjorth S, Carlsson A.
    J Med Chem; 1984 Jan 29; 27(1):45-51. PubMed ID: 6418888
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  • 9. Central dopaminergic and 5-hydroxytryptaminergic effects of C3-methylated derivatives of 8-hydroxy-2-(di-n-propylamino)tetralin.
    Mellin C, Björk L, Karlén A, Johansson AM, Sundell S, Kenne L, Nelson DL, Andén NE, Hacksell U.
    J Med Chem; 1988 Jun 29; 31(6):1130-40. PubMed ID: 2967376
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  • 10. (S)- and (R)-8-(di-n-propylamino)-6,7,8,9-tetrahydro-3H-benz[e]indole-1- carbaldehyde: a new class of orally active 5-HT1A-receptor agonists.
    Stjernlöf P, Gullme M, Elebring T, Andersson B, Wikström H, Lagerquist S, Svensson K, Ekman A, Carlsson A, Sundell S.
    J Med Chem; 1993 Jul 23; 36(15):2059-65. PubMed ID: 8340910
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  • 11. (R)- and (S)-8-acetyl-2-(dipropylamino)tetralin (LY-41): two novel 5-HT1A receptor agonists.
    Yu H, Liu Y, Hacksell U, Lewander T.
    Eur J Pharmacol; 1993 Jan 26; 231(1):69-76. PubMed ID: 8444282
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  • 12. (+)-cis-8-Hydroxy-1-methyl-2-(di-n-propylamino)tetralin: a potent and highly stereoselective 5-hydroxytryptamine receptor agonist.
    Arvidsson LE, Johansson AM, Hacksell U, Nilsson JL, Svensson K, Hjorth S, Magnusson T, Carlsson A, Andersson B, Wikström H.
    J Med Chem; 1987 Nov 26; 30(11):2105-9. PubMed ID: 2959776
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  • 13. Centrally acting serotonergic agents. Synthesis and structure-activity relationships of C-1- or C-3-substituted derivatives of 8-hydroxy-2-(di-n-propylamino)tetralin.
    Lin CH, Haadsma-Svensson SR, Lahti RA, McCall RB, Piercey MF, Schreur PJ, VonVoigtlander PF, Chidester CG.
    J Med Chem; 1993 Mar 19; 36(6):671-82. PubMed ID: 8459396
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  • 14. Thiophene analogs of naphthoxazines and 2-aminotetralins: bioisosteres with improved relative oral bioavailability, as compared to 5-OH-DPAT.
    Rodenhuis N, Timmerman W, Wikström HV, Dijkstra D.
    Eur J Pharmacol; 2000 Apr 14; 394(2-3):255-63. PubMed ID: 10771291
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  • 15. Resolved N,N-dialkylated 2-amino-8-hydroxytetralins: stereoselective interactions with 5-HT1A receptors in the brain.
    Björk L, Höök BB, Nelson DL, Andén NE, Hacksell U.
    J Med Chem; 1989 Apr 14; 32(4):779-83. PubMed ID: 2522991
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  • 16. Derivatives of 2-(dipropylamino)tetralin: effect of the C8-substituent on the interaction with 5-HT1A receptors.
    Liu Y, Yu H, Svensson BE, Cortizo L, Lewander T, Hacksell U.
    J Med Chem; 1993 Dec 24; 36(26):4221-9. PubMed ID: 7506312
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  • 17. Derivatives of cis-2-amino-8-hydroxy-1-methyltetralin: mixed 5-HT1A-receptor agonists and dopamine D2-receptor antagonists.
    Liu Y, Yu H, Mohell N, Nordvall G, Lewander T, Hacksell U.
    J Med Chem; 1995 Jan 06; 38(1):150-60. PubMed ID: 7530773
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  • 18. Additive hypothermic effects of the 5-HT1A receptor agonist 8-OH-DPAT and the dopamine D2/3 receptor agonist 7-OH-DPAT in the rat.
    Eltayb A, Lindblom S, Oerther S, Ahlenius S.
    Acta Physiol Scand; 2001 Jul 06; 172(3):205-9. PubMed ID: 11472307
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  • 19. (S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: a putative 5-HT1A-receptor antagonist.
    Hillver SE, Björk L, Li YL, Svensson B, Ross S, Andén NE, Hacksell U.
    J Med Chem; 1990 Jun 06; 33(6):1541-4. PubMed ID: 2140413
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  • 20. 5-Hydroxy-2-methyl-2-(di-n-propylamino)tetralin: synthesis and central pharmacological effects.
    Hacksell U, Arvidsson LE, Johansson AM, Nilsson JL, Sanchez D, Andersson B, Lindberg P, Wikström H, Hjorth S, Svensson K.
    Acta Pharm Suec; 1985 Jun 06; 22(2):65-74. PubMed ID: 2996294
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