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119 related items for PubMed ID: 8239647

  • 21. A single injection of fibronectin fragments into rabbit knee joints enhances catabolism in the articular cartilage followed by reparative responses but also induces systemic effects in the non-injected knee joints.
    Homandberg GA, Kang Y, Zhang J, Cole AA, Williams JM.
    Osteoarthritis Cartilage; 2001 Nov; 9(8):673-83. PubMed ID: 11795986
    [Abstract] [Full Text] [Related]

  • 22. Exposure of cartilage to a fibronectin fragment amplifies catabolic processes while also enhancing anabolic processes to limit damage.
    Homandberg GA, Wen C.
    J Orthop Res; 1998 Mar; 16(2):237-46. PubMed ID: 9621898
    [Abstract] [Full Text] [Related]

  • 23. Fibronectin fragments mediate matrix metalloproteinase upregulation and cartilage damage through proline rich tyrosine kinase 2, c-src, NF-kappaB and protein kinase Cdelta.
    Ding L, Guo D, Homandberg GA.
    Osteoarthritis Cartilage; 2009 Oct; 17(10):1385-92. PubMed ID: 19409294
    [Abstract] [Full Text] [Related]

  • 24. Fibronectin fragment inhibits xylosyltransferase-1 expression by regulating Sp1/Sp3- dependent transcription in articular chondrocytes.
    Hwang HS, Lee MH, Kim HA.
    Osteoarthritis Cartilage; 2019 May; 27(5):833-843. PubMed ID: 30685487
    [Abstract] [Full Text] [Related]

  • 25. The cartilage chondrolytic mechanism of fibronectin fragments involves MAP kinases: comparison of three fragments and native fibronectin.
    Ding L, Guo D, Homandberg GA.
    Osteoarthritis Cartilage; 2008 Oct; 16(10):1253-62. PubMed ID: 18396067
    [Abstract] [Full Text] [Related]

  • 26. Potential regulation of cartilage metabolism in osteoarthritis by fibronectin fragments.
    Homandberg GA.
    Front Biosci; 1999 Oct 15; 4():D713-30. PubMed ID: 10525477
    [Abstract] [Full Text] [Related]

  • 27. A fibronectin fragment induces type II collagen degradation by collagenase through an interleukin-1-mediated pathway.
    Yasuda T, Poole AR.
    Arthritis Rheum; 2002 Jan 15; 46(1):138-48. PubMed ID: 11817586
    [Abstract] [Full Text] [Related]

  • 28. The 45 kDa collagen-binding fragment of fibronectin induces matrix metalloproteinase-13 synthesis by chondrocytes and aggrecan degradation by aggrecanases.
    Stanton H, Ung L, Fosang AJ.
    Biochem J; 2002 May 15; 364(Pt 1):181-90. PubMed ID: 11988091
    [Abstract] [Full Text] [Related]

  • 29. The effects of hyaluronic acid on fibronectin fragment mediated cartilage chondrolysis in skeletally mature rabbits.
    Williams JM, Zhang J, Kang H, Ummadi V, Homandberg GA.
    Osteoarthritis Cartilage; 2003 Jan 15; 11(1):44-9. PubMed ID: 12505486
    [Abstract] [Full Text] [Related]

  • 30. Hyaluronic acid suppresses fibronectin fragment mediated cartilage chondrolysis: II. In vivo.
    Williams JM, Plaza V, Hui F, Wen C, Kuettner KE, Homandberg GA.
    Osteoarthritis Cartilage; 1997 Jul 15; 5(4):235-40. PubMed ID: 9404468
    [Abstract] [Full Text] [Related]

  • 31. Proteoglycan-degrading activity associated with the 40 kDa collagen-binding fragment of fibronectin.
    Chevalier X, Groult N, Emod I, Planchenault T.
    Br J Rheumatol; 1996 Jun 15; 35(6):506-14. PubMed ID: 8670569
    [Abstract] [Full Text] [Related]

  • 32. Effect of methylprednisolone acetate on proteoglycan and collagen metabolism of articular cartilage explants.
    Todhunter RJ, Fubini SL, Wootton JA, Lust G.
    J Rheumatol; 1996 Jul 15; 23(7):1207-13. PubMed ID: 8823694
    [Abstract] [Full Text] [Related]

  • 33. Fibronectin fragment-induced expression of matrix metalloproteinases is mediated by MyD88-dependent TLR-2 signaling pathway in human chondrocytes.
    Hwang HS, Park SJ, Cheon EJ, Lee MH, Kim HA.
    Arthritis Res Ther; 2015 Nov 12; 17():320. PubMed ID: 26563875
    [Abstract] [Full Text] [Related]

  • 34. Telopeptides of type II collagen upregulate proteinases and damage cartilage but are less effective than highly active fibronectin fragments.
    Guo D, Ding L, Homandberg GA.
    Inflamm Res; 2009 Mar 12; 58(3):161-9. PubMed ID: 19190855
    [Abstract] [Full Text] [Related]

  • 35. Fibronectin and proteoglycan synthesis in long term cultures of cartilage explants in Ham's F12 supplemented with insulin and calcium: effects of the addition of TGF-beta.
    Burton-Wurster N, Lust G.
    Arch Biochem Biophys; 1990 Nov 15; 283(1):27-33. PubMed ID: 2241173
    [Abstract] [Full Text] [Related]

  • 36. An N-terminal peptide from link protein stimulates proteoglycan biosynthesis in human articular cartilage in vitro.
    McKenna LA, Liu H, Sansom PA, Dean MF.
    Arthritis Rheum; 1998 Jan 15; 41(1):157-62. PubMed ID: 9433881
    [Abstract] [Full Text] [Related]

  • 37. Hyaluronan enhances cartilage repair through low grade tissue remodeling involving cytokines and matrix metalloproteinases.
    Homandberg GA, Ummadi V, Kang H.
    Inflamm Res; 2004 Oct 15; 53(10):534-43. PubMed ID: 15597148
    [Abstract] [Full Text] [Related]

  • 38. Altered biological activity of equine chondrocytes cultured in a three-dimensional fibrin matrix and supplemented with transforming growth factor beta-1.
    Fortier LA, Nixon AJ, Mohammed HO, Lust G.
    Am J Vet Res; 1997 Jan 15; 58(1):66-70. PubMed ID: 8989499
    [Abstract] [Full Text] [Related]

  • 39. Hyaluronan suppresses fibronectin fragment-mediated damage to human cartilage explant cultures by enhancing proteoglycan synthesis.
    Kang Y, Eger W, Koepp H, Williams JM, Kuettner KE, Homandberg GA.
    J Orthop Res; 1999 Nov 15; 17(6):858-69. PubMed ID: 10632453
    [Abstract] [Full Text] [Related]

  • 40. An N-terminal peptide from link protein can stimulate biosynthesis of collagen by human articular cartilage.
    Liu H, McKenna LA, Dean MF.
    Arch Biochem Biophys; 2000 Jun 01; 378(1):116-22. PubMed ID: 10871051
    [Abstract] [Full Text] [Related]

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