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190 related items for PubMed ID: 8246147

  • 1. Chelation of zinc antagonizes the neuromuscular blocking properties of the seven serotypes of botulinum neurotoxin as well as tetanus toxin.
    Simpson LL, Coffield JA, Bakry N.
    J Pharmacol Exp Ther; 1993 Nov; 267(2):720-7. PubMed ID: 8246147
    [Abstract] [Full Text] [Related]

  • 2. Lectins from Triticum vulgaris and Limax flavus are universal antagonists of botulinum neurotoxin and tetanus toxin.
    Bakry N, Kamata Y, Simpson LL.
    J Pharmacol Exp Ther; 1991 Sep; 258(3):830-6. PubMed ID: 1653841
    [Abstract] [Full Text] [Related]

  • 3. The binding fragment from tetanus toxin antagonizes the neuromuscular blocking actions of botulinum toxin.
    Simpson LL.
    J Pharmacol Exp Ther; 1984 Apr; 229(1):182-7. PubMed ID: 6707933
    [Abstract] [Full Text] [Related]

  • 4. Use of pharmacologic antagonists to deduce commonalities of biologic activity among clostridial neurotoxins.
    Simpson LL.
    J Pharmacol Exp Ther; 1988 Jun; 245(3):867-72. PubMed ID: 2455038
    [Abstract] [Full Text] [Related]

  • 5. Fragment C of tetanus toxin antagonizes the neuromuscular blocking properties of native tetanus toxin.
    Simpson LL.
    J Pharmacol Exp Ther; 1984 Mar; 228(3):600-4. PubMed ID: 6707911
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of vacuolar adenosine triphosphatase antagonizes the effects of clostridial neurotoxins but not phospholipase A2 neurotoxins.
    Simpson LL, Coffield JA, Bakry N.
    J Pharmacol Exp Ther; 1994 Apr; 269(1):256-62. PubMed ID: 8169833
    [Abstract] [Full Text] [Related]

  • 7. Ammonium chloride and methylamine hydrochloride antagonize clostridial neurotoxins.
    Simpson LL.
    J Pharmacol Exp Ther; 1983 Jun; 225(3):546-52. PubMed ID: 6864519
    [Abstract] [Full Text] [Related]

  • 8. Cleavage of SNAP-25 by botulinum toxin type A requires receptor-mediated endocytosis, pH-dependent translocation, and zinc.
    Kalandakanond S, Coffield JA.
    J Pharmacol Exp Ther; 2001 Mar; 296(3):980-6. PubMed ID: 11181932
    [Abstract] [Full Text] [Related]

  • 9. Exchanging the minimal cell binding fragments of tetanus neurotoxin in botulinum neurotoxin A and B impacts their toxicity at the neuromuscular junction and central neurons.
    Höltje M, Schulze S, Strotmeier J, Mahrhold S, Richter K, Binz T, Bigalke H, Ahnert-Hilger G, Rummel A.
    Toxicon; 2013 Dec 01; 75():108-21. PubMed ID: 23817019
    [Abstract] [Full Text] [Related]

  • 10. Tetanus toxin and neuronal membranes: the relationship between binding and toxicity.
    Bakry N, Kamata Y, Sorensen R, Simpson LL.
    J Pharmacol Exp Ther; 1991 Aug 01; 258(2):613-9. PubMed ID: 1865360
    [Abstract] [Full Text] [Related]

  • 11. [Structure and function of botulinum toxin].
    Fujii N.
    Hokkaido Igaku Zasshi; 1995 Jan 01; 70(1):19-28. PubMed ID: 7744367
    [Abstract] [Full Text] [Related]

  • 12. Identification of the site at which phospholipase A2 neurotoxins localize to produce their neuromuscular blocking effects.
    Simpson LL, Lautenslager GT, Kaiser II, Middlebrook JL.
    Toxicon; 1993 Jan 01; 31(1):13-26. PubMed ID: 8446959
    [Abstract] [Full Text] [Related]

  • 13. The interaction between aminoquinolines and presynaptically acting neurotoxins.
    Simpson LL.
    J Pharmacol Exp Ther; 1982 Jul 01; 222(1):43-8. PubMed ID: 6283072
    [Abstract] [Full Text] [Related]

  • 14. Botulinum neurotoxin type E: studies on mechanism of action and on structure-activity relationships.
    Simpson LL, Dasgupta BR.
    J Pharmacol Exp Ther; 1983 Jan 01; 224(1):135-40. PubMed ID: 6294275
    [Abstract] [Full Text] [Related]

  • 15. In vitro characterization of botulinum toxin types A, C and D action on human tissues: combined electrophysiologic, pharmacologic and molecular biologic approaches.
    Coffield JA, Bakry N, Zhang RD, Carlson J, Gomella LG, Simpson LL.
    J Pharmacol Exp Ther; 1997 Mar 01; 280(3):1489-98. PubMed ID: 9067339
    [Abstract] [Full Text] [Related]

  • 16. [Molecular mechanism of action of tetanus toxin and botulinum neurotoxins].
    Poulain B.
    Pathol Biol (Paris); 1994 Feb 01; 42(2):173-82. PubMed ID: 7916455
    [Abstract] [Full Text] [Related]

  • 17. Botulinum toxin and tetanus toxin recognize similar membrane determinants.
    Simpson LL.
    Brain Res; 1984 Jul 02; 305(1):177-80. PubMed ID: 6331597
    [Abstract] [Full Text] [Related]

  • 18. Use of monoclonal antibodies as probes for the structure and biological activity of botulinum neurotoxin.
    Simpson LL, Kamata Y, Kozaki S.
    J Pharmacol Exp Ther; 1990 Oct 02; 255(1):227-32. PubMed ID: 2213557
    [Abstract] [Full Text] [Related]

  • 19. Pharmacological experiments on the binding and internalization of the 50,000 dalton carboxyterminus of tetanus toxin at the cholinergic neuromuscular junction.
    Simpson LL.
    J Pharmacol Exp Ther; 1985 Jul 02; 234(1):100-5. PubMed ID: 2409271
    [Abstract] [Full Text] [Related]

  • 20. Action of botulinum A toxin and tetanus toxin on synaptic transmission.
    Dreyer F, Becker C, Bigalke H, Funk J, Penner R, Rosenberg F, Ziegler M.
    J Physiol (Paris); 1984 Jul 02; 79(4):252-8. PubMed ID: 6152293
    [Abstract] [Full Text] [Related]

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