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Journal Abstract Search

135 related items for PubMed ID: 8246226

  • 21. Guinea pig whole blood 5-lipoxygenase assay: utility in the assessment of potential 5-lipoxygenase inhibitors.
    Spaethe SM, Snyder DW, Pechous PA, Clarke T, VanAlstyne EL.
    Biochem Pharmacol; 1992 Jan 22; 43(2):377-82. PubMed ID: 1310855
    [Abstract] [Full Text] [Related]

  • 22. Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models.
    Carty TJ, Sweeney FJ, Griffiths RJ, Eskra JD, Ernest MJ, Pillar JS, Cheng JD, Loose LD, Joseph PA, Pazoles PP, Moore PF, Nagahisa A, Murase S, Kadin SB.
    Inflamm Res; 1997 May 22; 46(5):168-79. PubMed ID: 9197987
    [Abstract] [Full Text] [Related]

  • 23. N-[(arylmethoxy)phenyl] carboxylic acids, hydroxamic acids, tetrazoles, and sulfonyl carboxamides. Potent orally active leukotriene D4 antagonists of novel structure.
    Musser JH, Kreft AF, Bender RH, Kubrak DM, Grimes D, Carlson RP, Hand JM, Chang J.
    J Med Chem; 1990 Jan 22; 33(1):240-5. PubMed ID: 2104935
    [Abstract] [Full Text] [Related]

  • 24. Nitroxide metabolites from alkylhydroxylamines and N-hydroxyurea derivatives resulting from reductive inhibition of soybean lipoxygenase.
    Chamulitrat W, Mason RP, Riendeau D.
    J Biol Chem; 1992 May 15; 267(14):9574-9. PubMed ID: 1315759
    [Abstract] [Full Text] [Related]

  • 25. Synthesis of 1,5-diarylpyrazol-3-propanoic acids towards inhibition of cyclooxygenase-1/2 activity and 5-lipoxygenase-mediated LTB4 formation.
    Ergün BC, Nuñez MT, Labeaga L, Ledo F, Darlington J, Bain G, Cakir B, Banoglu E.
    Arzneimittelforschung; 2010 May 15; 60(8):497-505. PubMed ID: 20863006
    [Abstract] [Full Text] [Related]

  • 26. 5-Lipoxygenase and cyclooxygenase inhibitory active constituents from Qianghuo (Notopterygium incisum).
    Zschocke S, Lehner M, Bauer R.
    Planta Med; 1997 Jun 15; 63(3):203-6. PubMed ID: 9265192
    [Abstract] [Full Text] [Related]

  • 27. Studies on 5-lipoxygenase inhibitors. I. Synthesis and 5-lipoxygenase-inhibitory activity of novel hydroxamic acid derivatives.
    Yatabe T, Kawai Y, Oku T, Tanaka H.
    Chem Pharm Bull (Tokyo); 1998 Jun 15; 46(6):966-72. PubMed ID: 9658575
    [Abstract] [Full Text] [Related]

  • 28. Inhibition of 5-lipoxygenase: development of hydroxamic acids and hydroxyureas as potential therapeutic agents.
    Salmon JA, Jackson WP, Garland LG.
    Adv Prostaglandin Thromboxane Leukot Res; 1991 Jun 15; 21A():109-12. PubMed ID: 1847758
    [No Abstract] [Full Text] [Related]

  • 29. Selective inhibition of arachidonate 5-lipoxygenase by novel acetohydroxamic acids: biochemical assessment in vitro and ex vivo.
    Tateson JE, Randall RW, Reynolds CH, Jackson WP, Bhattacherjee P, Salmon JA, Garland LG.
    Br J Pharmacol; 1988 Jun 15; 94(2):528-39. PubMed ID: 2840160
    [Abstract] [Full Text] [Related]

  • 30. Differential effects of a series of hydroxamic acid derivatives on 5-lipoxygenase and cyclooxygenase from neutrophils and 12-lipoxygenase from platelets and their in vivo effects on inflammation and anaphylaxis.
    Huang FC, Shoupe TS, Lin CJ, Lee TD, Chan WK, Tan J, Schnapper M, Suh JT, Gordon RJ, Sonnino PA.
    J Med Chem; 1989 Aug 15; 32(8):1836-42. PubMed ID: 2502629
    [Abstract] [Full Text] [Related]

  • 31. Novel bishydroxamic acids as 5-lipoxygenase inhibitors.
    Ohemeng KA, Nguyen VN, Schwender CF, Singer M, Steber M, Ansell J, Hageman W.
    Bioorg Med Chem; 1994 Mar 15; 2(3):187-93. PubMed ID: 7922131
    [Abstract] [Full Text] [Related]

  • 32. Pseudoperoxidase activity of 5-lipoxygenase stimulated by potent benzofuranol and N-hydroxyurea inhibitors of the lipoxygenase reaction.
    Riendeau D, Falgueyret JP, Guay J, Ueda N, Yamamoto S.
    Biochem J; 1991 Feb 15; 274 ( Pt 1)(Pt 1):287-92. PubMed ID: 2001245
    [Abstract] [Full Text] [Related]

  • 33. Penta- and hexadienoic acid derivatives: a novel series of 5-lipoxygenase inhibitors.
    Malleron JL, Roussel G, Gueremy G, Ponsinet G, Robin JL, Terlain B, Tissieres JM.
    J Med Chem; 1990 Oct 15; 33(10):2744-9. PubMed ID: 2213827
    [Abstract] [Full Text] [Related]

  • 34. Methoxytetrahydropyrans. A new series of selective and orally potent 5-lipoxygenase inhibitors.
    Crawley GC, Dowell RI, Edwards PN, Foster SJ, McMillan RM, Walker ER, Waterson D, Bird TG, Bruneau P, Giroaeau JM.
    J Med Chem; 1992 Jul 10; 35(14):2600-9. PubMed ID: 1321908
    [Abstract] [Full Text] [Related]

  • 35. Sinapic acid phenethyl ester as a potent selective 5-lipoxygenase inhibitor: Synthesis and structure-activity relationship.
    Touaibia M, Hébert MJG, Levesque NA, Doiron JA, Doucet MS, Jean-François J, Cormier M, Boudreau LH, Surette ME.
    Chem Biol Drug Des; 2018 Nov 10; 92(5):1876-1887. PubMed ID: 29953727
    [Abstract] [Full Text] [Related]

  • 36. Inhibitory effects of maesanin and analogs on arachidonic acid metabolizing enzymes.
    Abourashed EA, Muhammad I, Resch M, Bauer R, el-Feraly FS, Hufford CD.
    Planta Med; 2001 Jun 10; 67(4):360-1. PubMed ID: 11458456
    [Abstract] [Full Text] [Related]

  • 37. 2-substituted indazolinones: orally active and selective 5-lipoxygenase inhibitors with anti-inflammatory activity.
    Foster SJ, Bruneau P, Walker ER, McMillan RM.
    Br J Pharmacol; 1990 Jan 10; 99(1):113-8. PubMed ID: 2110012
    [Abstract] [Full Text] [Related]

  • 38. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
    Rao PN, Chen QH, Knaus EE.
    J Med Chem; 2006 Mar 09; 49(5):1668-83. PubMed ID: 16509583
    [Abstract] [Full Text] [Related]

  • 39. Characterization of CGS 8515 as a selective 5-lipoxygenase (5-LO) inhibitor.
    Ku EC, Raychaudhuri A, Ghai G, Kimble EF, Lee WH, Colombo C, Dotson R, White D, Oglesby TD, Wasley JW.
    Adv Prostaglandin Thromboxane Leukot Res; 1989 Mar 09; 19():86-9. PubMed ID: 2526568
    [Abstract] [Full Text] [Related]

  • 40.
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