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2. P-glycoprotein-mediated renal tubular secretion of digoxin: the toxicological significance of the urine-blood barrier model. Ito S, Woodland C, Harper PA, Koren G. Life Sci; 1993; 53(2):PL25-31. PubMed ID: 8100040 [Abstract] [Full Text] [Related]
4. Energy-dependent transport of digoxin across renal tubular cell monolayers (LLC-PK1). Ito S, Koren G, Harper PA, Silverman M. Can J Physiol Pharmacol; 1993 Jan; 71(1):40-7. PubMed ID: 8099844 [Abstract] [Full Text] [Related]
5. Toxic digoxin-drug interactions: the major role of renal P-glycoprotein. Koren G, Woodland C, Ito S. Vet Hum Toxicol; 1998 Feb; 40(1):45-6. PubMed ID: 9467211 [Abstract] [Full Text] [Related]
6. A model for the prediction of digoxin-drug interactions at the renal tubular cell level. Woodland C, Ito S, Koren G. Ther Drug Monit; 1998 Apr; 20(2):134-8. PubMed ID: 9558126 [Abstract] [Full Text] [Related]
9. Digoxin-cyclosporin A interaction: modulation of the multidrug transporter P-glycoprotein in the kidney. Okamura N, Hirai M, Tanigawara Y, Tanaka K, Yasuhara M, Ueda K, Komano T, Hori R. J Pharmacol Exp Ther; 1993 Sep; 266(3):1614-9. PubMed ID: 8103797 [Abstract] [Full Text] [Related]
12. P-glycoprotein system as a determinant of drug interactions: the case of digoxin-verapamil. Verschraagen M, Koks CH, Schellens JH, Beijnen JH. Pharmacol Res; 1999 Oct; 40(4):301-6. PubMed ID: 10527640 [Abstract] [Full Text] [Related]
13. MDR1-mediated interaction of digoxin with antiarrhythmic or antianginal drugs. Kakumoto M, Takara K, Sakaeda T, Tanigawara Y, Kita T, Okumura K. Biol Pharm Bull; 2002 Dec; 25(12):1604-7. PubMed ID: 12499648 [Abstract] [Full Text] [Related]
17. Renal tubular cell handling of digoxin and ouabain--in vitro study using LLC-PK1 cell lines. Ito S, Harper PA, Koren G. Toxicol Lett; 1990 Sep; 53(1-2):189-91. PubMed ID: 2219165 [No Abstract] [Full Text] [Related]
18. Characterization of the major metabolites of verapamil as substrates and inhibitors of P-glycoprotein. Pauli-Magnus C, von Richter O, Burk O, Ziegler A, Mettang T, Eichelbaum M, Fromm MF. J Pharmacol Exp Ther; 2000 May; 293(2):376-82. PubMed ID: 10773005 [Abstract] [Full Text] [Related]
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