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280 related items for PubMed ID: 8247013

  • 1. Dominant and nondominant negative C-erbA beta 1 receptors associated with thyroid hormone resistance syndromes augment 12-O-tetradecanoyl-phorbol-13-acetate induction of the collagenase promoter and exhibit defective 3,5,3'-triiodothyronine-mediated repression.
    Ways DK, Qin W, Cook P, Parker PJ, Menke JB, Hao E, Smith AM, Jones C, Hershman JM, Geffner ME.
    Mol Endocrinol; 1993 Sep; 7(9):1112-20. PubMed ID: 8247013
    [Abstract] [Full Text] [Related]

  • 2. Divergent dimerization properties of mutant beta 1 thyroid hormone receptors are associated with different dominant negative activities.
    Hao E, Menke JB, Smith AM, Jones C, Geffner ME, Hershman JM, Wuerth JP, Samuels HH, Ways DK, Usala SJ.
    Mol Endocrinol; 1994 Jul; 8(7):841-51. PubMed ID: 7984146
    [Abstract] [Full Text] [Related]

  • 3. Effects of chronic phorbol ester treatment on protein kinase C activity, content, and gene expression in the human monoblastoid U937 cell.
    Ways DK, Qin W, Garris TO, Chen J, Hao E, Cooper DR, Usala SJ, Parker PJ, Cook PP.
    Cell Growth Differ; 1994 Feb; 5(2):161-9. PubMed ID: 8180129
    [Abstract] [Full Text] [Related]

  • 4. A homozygous deletion in the c-erbA beta thyroid hormone receptor gene in a patient with generalized thyroid hormone resistance: isolation and characterization of the mutant receptor.
    Usala SJ, Menke JB, Watson TL, Wondisford FE, Weintraub BD, Bérard J, Bradley WE, Ono S, Mueller OT, Bercu BB.
    Mol Endocrinol; 1991 Mar; 5(3):327-35. PubMed ID: 1653889
    [Abstract] [Full Text] [Related]

  • 5. Dominant-negative mutant thyroid hormone receptors prevent transcription from Xenopus thyroid hormone receptor beta gene promoter in response to thyroid hormone in Xenopus tadpoles in vivo.
    Ulisse S, Esslemont G, Baker BS, Krishna V, Chatterjee K, Tata JR.
    Proc Natl Acad Sci U S A; 1996 Feb 06; 93(3):1205-9. PubMed ID: 8577741
    [Abstract] [Full Text] [Related]

  • 6. Triiodothyroacetic acid has unique potential for therapy of resistance to thyroid hormone.
    Takeda T, Suzuki S, Liu RT, DeGroot LJ.
    J Clin Endocrinol Metab; 1995 Jul 06; 80(7):2033-40. PubMed ID: 7608251
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  • 8. An arginine to histidine mutation in codon 311 of the C-erbA beta gene results in a mutant thyroid hormone receptor that does not mediate a dominant negative phenotype.
    Geffner ME, Su F, Ross NS, Hershman JM, Van Dop C, Menke JB, Hao E, Stanzak RK, Eaton T, Samuels HH.
    J Clin Invest; 1993 Feb 06; 91(2):538-46. PubMed ID: 8381821
    [Abstract] [Full Text] [Related]

  • 9. Interaction of human beta 1 thyroid hormone receptor and its mutants with DNA and retinoid X receptor beta. T3 response element-dependent dominant negative potency.
    Meier CA, Parkison C, Chen A, Ashizawa K, Meier-Heusler SC, Muchmore P, Cheng SY, Weintraub BD.
    J Clin Invest; 1993 Oct 06; 92(4):1986-93. PubMed ID: 8408652
    [Abstract] [Full Text] [Related]

  • 10. A conserved C-terminal sequence that is deleted in v-ErbA is essential for the biological activities of c-ErbA (the thyroid hormone receptor).
    Saatcioglu F, Bartunek P, Deng T, Zenke M, Karin M.
    Mol Cell Biol; 1993 Jun 06; 13(6):3675-85. PubMed ID: 8098843
    [Abstract] [Full Text] [Related]

  • 11. c-ErbA, but not v-ErbA, competes with a putative erythroid repressor for binding to the carbonic anhydrase II promoter.
    Rascle A, Ghysdael J, Samarut J.
    Oncogene; 1994 Oct 06; 9(10):2853-67. PubMed ID: 7916146
    [Abstract] [Full Text] [Related]

  • 12. Functional characterization of the rat growth hormone promoter elements required for induction by thyroid hormone with and without a co-transfected beta type thyroid hormone receptor.
    Brent GA, Larsen PR, Harney JW, Koenig RJ, Moore DD.
    J Biol Chem; 1989 Jan 05; 264(1):178-82. PubMed ID: 2909514
    [Abstract] [Full Text] [Related]

  • 13. Thyroid hormone receptor-beta mutants associated with generalized resistance to thyroid hormone show defects in their ligand-sensitive repression function.
    Piedrafita FJ, Ortiz MA, Pfahl M.
    Mol Endocrinol; 1995 Nov 05; 9(11):1533-48. PubMed ID: 8584031
    [Abstract] [Full Text] [Related]

  • 14. Thyroid hormone resistance syndrome. Inhibition of normal receptor function by mutant thyroid hormone receptors.
    Chatterjee VK, Nagaya T, Madison LD, Datta S, Rentoumis A, Jameson JL.
    J Clin Invest; 1991 Jun 05; 87(6):1977-84. PubMed ID: 2040690
    [Abstract] [Full Text] [Related]

  • 15. Dominant negative inhibition by mutant thyroid hormone receptors is thyroid hormone response element and receptor isoform specific.
    Zavacki AM, Harney JW, Brent GA, Larsen PR.
    Mol Endocrinol; 1993 Oct 05; 7(10):1319-30. PubMed ID: 8264663
    [Abstract] [Full Text] [Related]

  • 16. An arginine to histidine mutation in codon 315 of the c-erbA beta thyroid hormone receptor in a kindred with generalized resistance to thyroid hormones results in a receptor with significant 3,5,3'-triiodothyronine binding activity.
    Cugini CD, Leidy JW, Chertow BS, Bérard J, Bradley WE, Menke JB, Hao EH, Usala SJ.
    J Clin Endocrinol Metab; 1992 May 05; 74(5):1164-70. PubMed ID: 1314846
    [Abstract] [Full Text] [Related]

  • 17. Synergistic activation of the rat growth hormone promoter by Pit-1 and the thyroid hormone receptor.
    Schaufele F, West BL, Baxter JD.
    Mol Endocrinol; 1992 Apr 05; 6(4):656-65. PubMed ID: 1584227
    [Abstract] [Full Text] [Related]

  • 18. Dominant negative transcriptional regulation by a mutant thyroid hormone receptor-beta in a family with generalized resistance to thyroid hormone.
    Sakurai A, Miyamoto T, Refetoff S, DeGroot LJ.
    Mol Endocrinol; 1990 Dec 05; 4(12):1988-94. PubMed ID: 2082193
    [Abstract] [Full Text] [Related]

  • 19. The thyroid hormone receptor interferes with transcriptional activation via the AP-1 complex.
    Schmidt ED, Cramer SJ, Offringa R.
    Biochem Biophys Res Commun; 1993 Apr 15; 192(1):151-60. PubMed ID: 8386506
    [Abstract] [Full Text] [Related]

  • 20. Understanding the molecular mechanism of dominant negative action of mutant thyroid hormone beta 1-receptors: the important role of the wild-type/mutant receptor heterodimer.
    Zhu XG, Yu CL, McPhie P, Wong R, Cheng SY.
    Endocrinology; 1996 Feb 15; 137(2):712-21. PubMed ID: 8593822
    [Abstract] [Full Text] [Related]


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