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188 related items for PubMed ID: 8251496

  • 1. Alternative model for mechanism-based inhibition of Escherichia coli ribonucleotide reductase by 2'-azido-2'-deoxyuridine 5'-diphosphate.
    Salowe S, Bollinger JM, Ator M, Stubbe J, McCraken J, Peisach J, Samano MC, Robins MJ.
    Biochemistry; 1993 Nov 30; 32(47):12749-60. PubMed ID: 8251496
    [Abstract] [Full Text] [Related]

  • 2. Products of the inactivation of ribonucleoside diphosphate reductase from Escherichia coli with 2'-azido-2'-deoxyuridine 5'-diphosphate.
    Salowe SP, Ator MA, Stubbe J.
    Biochemistry; 1987 Jun 16; 26(12):3408-16. PubMed ID: 3307907
    [Abstract] [Full Text] [Related]

  • 3. Structure of the nitrogen-centered radical formed during inactivation of E. coli ribonucleotide reductase by 2'-azido-2'-deoxyuridine-5'-diphosphate: trapping of the 3'-ketonucleotide.
    Fritscher J, Artin E, Wnuk S, Bar G, Robblee JH, Kacprzak S, Kaupp M, Griffin RG, Bennati M, Stubbe J.
    J Am Chem Soc; 2005 Jun 01; 127(21):7729-38. PubMed ID: 15913363
    [Abstract] [Full Text] [Related]

  • 4. Inactivation of ribonucleotide reductase by (E)-2'-fluoromethylene-2'-deoxycytidine 5'-diphosphate: a paradigm for nucleotide mechanism-based inhibitors.
    van der Donk WA, Yu G, Silva DJ, Stubbe J, McCarthy JR, Jarvi ET, Matthews DP, Resvick RJ, Wagner E.
    Biochemistry; 1996 Jun 25; 35(25):8381-91. PubMed ID: 8679596
    [Abstract] [Full Text] [Related]

  • 5. Interaction of C225SR1 mutant subunit of ribonucleotide reductase with R2 and nucleoside diphosphates: tales of a suicidal enzyme.
    Mao SS, Holler TP, Bollinger JM, Yu GX, Johnston MI, Stubbe J.
    Biochemistry; 1992 Oct 13; 31(40):9744-51. PubMed ID: 1390750
    [Abstract] [Full Text] [Related]

  • 6. EPR distance measurements support a model for long-range radical initiation in E. coli ribonucleotide reductase.
    Bennati M, Robblee JH, Mugnaini V, Stubbe J, Freed JH, Borbat P.
    J Am Chem Soc; 2005 Nov 02; 127(43):15014-5. PubMed ID: 16248626
    [Abstract] [Full Text] [Related]

  • 7.
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  • 8. Inactivation of Escherichia coli ribonucleotide reductase by 2'-deoxy-2'-mercaptouridine 5'-diphosphate. Electron paramagnetic resonance evidence for a transient protein perthiyl radical.
    Covès J, Le Hir de Fallois L, Le Pape L, Décout JL, Fontecave M.
    Biochemistry; 1996 Jul 02; 35(26):8595-602. PubMed ID: 8679621
    [Abstract] [Full Text] [Related]

  • 9. Mechanism of inactivation of Escherichia coli ribonucleotide reductase by 2'-chloro-2'-deoxyuridine 5'-diphosphate: evidence for generation of a 2'-deoxy-3'-ketonucleotide via a net 1,2 hydrogen shift.
    Ator MA, Stubbe J.
    Biochemistry; 1985 Dec 03; 24(25):7214-21. PubMed ID: 3910098
    [Abstract] [Full Text] [Related]

  • 10. Detection of a new substrate-derived radical during inactivation of ribonucleotide reductase from Escherichia coli by gemcitabine 5'-diphosphate.
    van der Donk WA, Yu G, Pérez L, Sanchez RJ, Stubbe J, Samano V, Robins MJ.
    Biochemistry; 1998 May 05; 37(18):6419-26. PubMed ID: 9572859
    [Abstract] [Full Text] [Related]

  • 11. Cysteinyl and substrate radical formation in active site mutant E441Q of Escherichia coli class I ribonucleotide reductase.
    Persson AL, Sahlin M, Sjöberg BM.
    J Biol Chem; 1998 Nov 20; 273(47):31016-20. PubMed ID: 9812999
    [Abstract] [Full Text] [Related]

  • 12. Stereodefined synthesis of O3'-labeled uracil nucleosides. 3'-[(17)O]-2'-Azido-2'-deoxyuridine 5'-diphosphate as a probe for the mechanism of inactivation of ribonucleotide reductases.
    Wnuk SF, Chowdhury SM, Garcia PI, Robins MJ.
    J Org Chem; 2002 Mar 22; 67(6):1816-9. PubMed ID: 11895397
    [Abstract] [Full Text] [Related]

  • 13. A substrate radical intermediate in the reaction between ribonucleotide reductase from Escherichia coli and 2'-azido-2'-deoxynucleoside diphosphates.
    Sjöberg BM, Gräslund A, Eckstein F.
    J Biol Chem; 1983 Jul 10; 258(13):8060-7. PubMed ID: 6305969
    [Abstract] [Full Text] [Related]

  • 14. A model for the role of multiple cysteine residues involved in ribonucleotide reduction: amazing and still confusing.
    Mao SS, Holler TP, Yu GX, Bollinger JM, Booker S, Johnston MI, Stubbe J.
    Biochemistry; 1992 Oct 13; 31(40):9733-43. PubMed ID: 1382592
    [Abstract] [Full Text] [Related]

  • 15. High-field EPR detection of a disulfide radical anion in the reduction of cytidine 5'-diphosphate by the E441Q R1 mutant of Escherichia coli ribonucleotide reductase.
    Lawrence CC, Bennati M, Obias HV, Bar G, Griffin RG, Stubbe J.
    Proc Natl Acad Sci U S A; 1999 Aug 03; 96(16):8979-84. PubMed ID: 10430881
    [Abstract] [Full Text] [Related]

  • 16. Restoring proper radical generation by azide binding to the iron site of the E238A mutant R2 protein of ribonucleotide reductase from Escherichia coli.
    Assarsson M, Andersson ME, Högbom M, Persson BO, Sahlin M, Barra AL, Sjöberg BM, Nordlund P, Gräslund A.
    J Biol Chem; 2001 Jul 20; 276(29):26852-9. PubMed ID: 11328804
    [Abstract] [Full Text] [Related]

  • 17. High-field pulsed electron-electron double resonance spectroscopy to determine the orientation of the tyrosyl radicals in ribonucleotide reductase.
    Denysenkov VP, Prisner TF, Stubbe J, Bennati M.
    Proc Natl Acad Sci U S A; 2006 Sep 05; 103(36):13386-90. PubMed ID: 16938868
    [Abstract] [Full Text] [Related]

  • 18. Mechanism of ribonucleotide reductase from herpes simplex virus type 1. Evidence for 3' carbon-hydrogen bond cleavage and inactivation by nucleotide analogs.
    Ator MA, Stubbe J, Spector T.
    J Biol Chem; 1986 Mar 15; 261(8):3595-9. PubMed ID: 3005293
    [Abstract] [Full Text] [Related]

  • 19. Kinetics of transient radicals in Escherichia coli ribonucleotide reductase. Formation of a new tyrosyl radical in mutant protein R2.
    Katterle B, Sahlin M, Schmidt PP, Pötsch S, Logan DT, Gräslund A, Sjöberg BM.
    J Biol Chem; 1997 Apr 18; 272(16):10414-21. PubMed ID: 9099682
    [Abstract] [Full Text] [Related]

  • 20. Electron transfer properties of the R2 protein of ribonucleotide reductase from Escherichia coli.
    Silva KE, Elgren TE, Que L, Stankovich MT.
    Biochemistry; 1995 Oct 31; 34(43):14093-103. PubMed ID: 7578006
    [Abstract] [Full Text] [Related]

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