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546 related items for PubMed ID: 8257416

  • 1. Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.
    Arcaro A, Wymann MP.
    Biochem J; 1993 Dec 01; 296 ( Pt 2)(Pt 2):297-301. PubMed ID: 8257416
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  • 2. Platelet-derived growth factor-induced phosphatidylinositol 3-kinase activation mediates actin rearrangements in fibroblasts.
    Wymann M, Arcaro A.
    Biochem J; 1994 Mar 15; 298 Pt 3(Pt 3):517-20. PubMed ID: 8141762
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  • 5. Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase.
    Okada T, Sakuma L, Fukui Y, Hazeki O, Ui M.
    J Biol Chem; 1994 Feb 04; 269(5):3563-7. PubMed ID: 8106399
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  • 7. Phosphatidylinositol (3,4,5)-trisphosphate stimulates phosphorylation of pleckstrin in human platelets.
    Zhang J, Falck JR, Reddy KK, Abrams CS, Zhao W, Rittenhouse SE.
    J Biol Chem; 1995 Sep 29; 270(39):22807-10. PubMed ID: 7559410
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  • 8. Phosphatidylinositol 3-kinase mediates chemoattractant-stimulated, CD11b/CD18-dependent cell-cell adhesion of human neutrophils: evidence for an ERK-independent pathway.
    Capodici C, Hanft S, Feoktistov M, Pillinger MH.
    J Immunol; 1998 Feb 15; 160(4):1901-9. PubMed ID: 9469452
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  • 9. Cyclic AMP-increasing agents interfere with chemoattractant-induced respiratory burst in neutrophils as a result of the inhibition of phosphatidylinositol 3-kinase rather than receptor-operated Ca2+ influx.
    Ahmed MU, Hazeki K, Hazeki O, Katada T, Ui M.
    J Biol Chem; 1995 Oct 06; 270(40):23816-22. PubMed ID: 7559558
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  • 10. Regulation of phosphatidylinositol 3-kinase activity and phosphatidylinositol 3,4,5-trisphosphate accumulation by neutrophil priming agents.
    Cadwallader KA, Condliffe AM, McGregor A, Walker TR, White JF, Stephens LR, Chilvers ER.
    J Immunol; 2002 Sep 15; 169(6):3336-44. PubMed ID: 12218155
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  • 11. Antagonists of phosphatidylinositol 3-kinase block activation of several novel protein kinases in neutrophils.
    Ding J, Vlahos CJ, Liu R, Brown RF, Badwey JA.
    J Biol Chem; 1995 May 12; 270(19):11684-91. PubMed ID: 7744808
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  • 12. Protein kinase C activity is not involved in N-formylmethionyl-leucyl-phenylalanine-induced phospholipase D activation in human neutrophils, but is essential for concomitant NADPH oxidase activation: studies with a staurosporine analogue with improved selectivity for protein kinase C.
    Kessels GC, Krause KH, Verhoeven AJ.
    Biochem J; 1993 Jun 15; 292 ( Pt 3)(Pt 3):781-5. PubMed ID: 8391255
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  • 13. Enhancement of chemotactic peptide-induced activation of phosphoinositide 3-kinase by granulocyte-macrophage colony-stimulating factor and its relation to the cytokine-mediated priming of neutrophil superoxide-anion production.
    Kodama T, Hazeki K, Hazeki O, Okada T, Ui M.
    Biochem J; 1999 Jan 15; 337 ( Pt 2)(Pt 2):201-9. PubMed ID: 9882616
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  • 14. The phosphatidylinositol 3-kinase inhibitor wortmannin markedly reduces chemotactic peptide-induced locomotion and increases in cytoskeletal actin in human neutrophils.
    Niggli V, Keller H.
    Eur J Pharmacol; 1997 Sep 17; 335(1):43-52. PubMed ID: 9371545
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  • 15. Increased breakdown of phosphatidylinositol 4,5-bisphosphate is not an initiating factor for actin assembly in human neutrophils.
    Bengtsson T, Rundquist I, Stendahl O, Wymann MP, Andersson T.
    J Biol Chem; 1988 Nov 25; 263(33):17385-9. PubMed ID: 2846563
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  • 16. Demethoxyviridin and wortmannin block phospholipase C and D activation in the human neutrophil.
    Bonser RW, Thompson NT, Randall RW, Tateson JE, Spacey GD, Hodson HF, Garland LG.
    Br J Pharmacol; 1991 May 25; 103(1):1237-41. PubMed ID: 1908735
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  • 17. Wortmannin inhibits insulin secretion in pancreatic islets and beta-TC3 cells independent of its inhibition of phosphatidylinositol 3-kinase.
    Gao Z, Konrad RJ, Collins H, Matschinsky FM, Rothenberg PL, Wolf BA.
    Diabetes; 1996 Jul 25; 45(7):854-62. PubMed ID: 8666133
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  • 18. Thrombin stimulates wortmannin-inhibitable phosphoinositide 3-kinase and membrane blebbing in CHRF-288 cells.
    Vemuri GS, Zhang J, Huang R, Keen JH, Rittenhouse SE.
    Biochem J; 1996 Mar 15; 314 ( Pt 3)(Pt 3):805-10. PubMed ID: 8615773
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  • 19. Initiation and maintenance of NGF-stimulated neurite outgrowth requires activation of a phosphoinositide 3-kinase.
    Jackson TR, Blader IJ, Hammonds-Odie LP, Burga CR, Cooke F, Hawkins PT, Wolf AG, Heldman KA, Theibert AB.
    J Cell Sci; 1996 Feb 15; 109 ( Pt 2)(0 2):289-300. PubMed ID: 8838652
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  • 20. Phosphorylation of the platelet p47 phosphoprotein is mediated by the lipid products of phosphoinositide 3-kinase.
    Toker A, Bachelot C, Chen CS, Falck JR, Hartwig JH, Cantley LC, Kovacsovics TJ.
    J Biol Chem; 1995 Dec 08; 270(49):29525-31. PubMed ID: 7493994
    [Abstract] [Full Text] [Related]


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