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PUBMED FOR HANDHELDS

Journal Abstract Search


131 related items for PubMed ID: 8263786

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  • 3. Effects of a 2,3-oxidosqualene-lanosterol cyclase inhibitor 2,3:22,23-dioxidosqualene and 24,25-epoxycholesterol on the regulation of cholesterol biosynthesis in human hepatoma cell line HepG2.
    Dollis D, Schuber F.
    Biochem Pharmacol; 1994 Jul 05; 48(1):49-57. PubMed ID: 8043030
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  • 6. Inhibition of cholesterol biosynthesis in 3T3 fibroblasts by 2-aza-2,3-dihydrosqualene, a rationally designed 2,3-oxidosqualene cyclase inhibitor.
    Gerst N, Schuber F, Viola F, Cattel L.
    Biochem Pharmacol; 1986 Dec 01; 35(23):4243-50. PubMed ID: 3790151
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  • 9. N-[(1,5,9)-trimethyl-decyl]-4 alpha,10-dimethyl-8-aza-trans-decal-3 beta-ol a novel potent inhibitor of 2,3-oxidosqualene cycloartenol and lanosterol cyclases.
    Taton M, Benveniste P, Rahier A.
    Biochem Biophys Res Commun; 1986 Jul 31; 138(2):764-70. PubMed ID: 3741433
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  • 12. Effects of a novel 2,3-oxidosqualene cyclase inhibitor on the regulation of cholesterol biosynthesis in HepG2 cells.
    Mark M, Muller P, Maier R, Eisele B.
    J Lipid Res; 1996 Jan 31; 37(1):148-58. PubMed ID: 8820110
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  • 13. RPR 107393, a potent squalene synthase inhibitor and orally effective cholesterol-lowering agent: comparison with inhibitors of HMG-CoA reductase.
    Amin D, Rutledge RZ, Needle SN, Galczenski HF, Neuenschwander K, Scotese AC, Maguire MP, Bush RC, Hele DJ, Bilder GE, Perrone MH.
    J Pharmacol Exp Ther; 1997 May 31; 281(2):746-52. PubMed ID: 9152381
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  • 14. Lord of the rings--the mechanism for oxidosqualene:lanosterol cyclase becomes crystal clear.
    Huff MW, Telford DE.
    Trends Pharmacol Sci; 2005 Jul 31; 26(7):335-40. PubMed ID: 15951028
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  • 16. Quinuclidine inhibitors of 2,3-oxidosqualene cyclase-lanosterol synthase: optimization from lipid profiles.
    Brown GR, Hollinshead DM, Stokes ES, Clarke DS, Eakin MA, Foubister AJ, Glossop SC, Griffiths D, Johnson MC, McTaggart F, Mirrlees DJ, Smith GJ, Wood R.
    J Med Chem; 1999 Apr 08; 42(7):1306-11. PubMed ID: 10197973
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  • 17. Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro.
    Flint OP, Masters BA, Gregg RE, Durham SK.
    Toxicol Appl Pharmacol; 1997 Jul 08; 145(1):91-8. PubMed ID: 9221828
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  • 18. Inhibitors of cholesterol biosynthesis. Further studies of the metabolism of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one in rat liver preparations.
    Monger DJ, Schroepfer GJ.
    Chem Phys Lipids; 1988 May 08; 47(1):21-46. PubMed ID: 3396133
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  • 20. [Inhibition of cholesterol biosynthesis in rabbit hepatocytes by 3-beta-(omega-hydroxyalkoxy)cholest-5-enes].
    Maliugin AV, Novikov DK, Kosykh VA, Kosenkov EI, Medvedeva NV, Valentinova NV, Shteĭnshneĭder AIa, Misharin AIu.
    Bioorg Khim; 1996 Jul 08; 22(7):541-7. PubMed ID: 8992960
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