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Journal Abstract Search

228 related items for PubMed ID: 8265621

  • 1. Human cytochrome P450 3A4: enzymatic properties of a purified recombinant fusion protein containing NADPH-P450 reductase.
    Shet MS, Fisher CW, Holmans PL, Estabrook RW.
    Proc Natl Acad Sci U S A; 1993 Dec 15; 90(24):11748-52. PubMed ID: 8265621
    [Abstract] [Full Text] [Related]

  • 2. The effects of cytochrome b5, NADPH-P450 reductase, and lipid on the rate of 6 beta-hydroxylation of testosterone as catalyzed by a human P450 3A4 fusion protein.
    Shet MS, Faulkner KM, Holmans PL, Fisher CW, Estabrook RW.
    Arch Biochem Biophys; 1995 Apr 20; 318(2):314-21. PubMed ID: 7733659
    [Abstract] [Full Text] [Related]

  • 3. Reconstitution premixes for assays using purified recombinant human cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b5.
    Shaw PM, Hosea NA, Thompson DV, Lenius JM, Guengerich FP.
    Arch Biochem Biophys; 1997 Dec 01; 348(1):107-15. PubMed ID: 9390180
    [Abstract] [Full Text] [Related]

  • 4. High-level expression in Escherichia coli of enzymatically active fusion proteins containing the domains of mammalian cytochromes P450 and NADPH-P450 reductase flavoprotein.
    Fisher CW, Shet MS, Caudle DL, Martin-Wixtrom CA, Estabrook RW.
    Proc Natl Acad Sci U S A; 1992 Nov 15; 89(22):10817-21. PubMed ID: 1438282
    [Abstract] [Full Text] [Related]

  • 5. Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes.
    Yamazaki H, Nakano M, Imai Y, Ueng YF, Guengerich FP, Shimada T.
    Arch Biochem Biophys; 1996 Jan 15; 325(2):174-82. PubMed ID: 8561495
    [Abstract] [Full Text] [Related]

  • 6. Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.
    Yamazaki H, Johnson WW, Ueng YF, Shimada T, Guengerich FP.
    J Biol Chem; 1996 Nov 01; 271(44):27438-44. PubMed ID: 8910324
    [Abstract] [Full Text] [Related]

  • 7. Roles of divalent metal ions in oxidations catalyzed by recombinant cytochrome P450 3A4 and replacement of NADPH--cytochrome P450 reductase with other flavoproteins, ferredoxin, and oxygen surrogates.
    Yamazaki H, Ueng YF, Shimada T, Guengerich FP.
    Biochemistry; 1995 Jul 04; 34(26):8380-9. PubMed ID: 7599128
    [Abstract] [Full Text] [Related]

  • 8. Coexpression of genetically engineered fused enzyme between yeast NADPH-P450 reductase and human cytochrome P450 3A4 and human cytochrome b5 in yeast.
    Hayashi K, Sakaki T, Kominami S, Inouye K, Yabusaki Y.
    Arch Biochem Biophys; 2000 Sep 01; 381(1):164-70. PubMed ID: 11019832
    [Abstract] [Full Text] [Related]

  • 9. Molecular characterization of specifically active recombinant fused enzymes consisting of CYP3A4, NADPH-cytochrome P450 oxidoreductase, and cytochrome b5.
    Inui H, Maeda A, Ohkawa H.
    Biochemistry; 2007 Sep 04; 46(35):10213-21. PubMed ID: 17691855
    [Abstract] [Full Text] [Related]

  • 10. Construction of a human cytochrome P450 1A1: rat NADPH-cytochrome P450 reductase fusion protein cDNA and expression in Escherichia coli, purification, and catalytic properties of the enzyme in bacterial cells and after purification.
    Chun YJ, Shimada T, Guengerich FP.
    Arch Biochem Biophys; 1996 Jun 01; 330(1):48-58. PubMed ID: 8651703
    [Abstract] [Full Text] [Related]

  • 11. The omega-hydroxlyation of lauric acid: oxidation of 12-hydroxlauric acid to dodecanedioic acid by a purified recombinant fusion protein containing P450 4A1 and NADPH-P450 reductase.
    Shet Ms, Fisher CW, Holmans PL, Estabrook RW.
    Arch Biochem Biophys; 1996 Jun 01; 330(1):199-208. PubMed ID: 8651697
    [Abstract] [Full Text] [Related]

  • 12. Optimization of yeast-expressed human liver cytochrome P450 3A4 catalytic activities by coexpressing NADPH-cytochrome P450 reductase and cytochrome b5.
    Peyronneau MA, Renaud JP, Truan G, Urban P, Pompon D, Mansuy D.
    Eur J Biochem; 1992 Jul 01; 207(1):109-16. PubMed ID: 1628642
    [Abstract] [Full Text] [Related]

  • 13. Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions.
    Yamazaki H, Gillam EM, Dong MS, Johnson WW, Guengerich FP, Shimada T.
    Arch Biochem Biophys; 1997 Jun 15; 342(2):329-37. PubMed ID: 9186495
    [Abstract] [Full Text] [Related]

  • 14. Expression of cytochrome P450 3A5 in Escherichia coli: effects of 5' modification, purification, spectral characterization, reconstitution conditions, and catalytic activities.
    Gillam EM, Guo Z, Ueng YF, Yamazaki H, Cock I, Reilly PE, Hooper WD, Guengerich FP.
    Arch Biochem Biophys; 1995 Mar 10; 317(2):374-84. PubMed ID: 7893152
    [Abstract] [Full Text] [Related]

  • 15. Purification and enzymatic properties of a recombinant fusion protein expressed in Escherichia coli containing the domains of bovine P450 17A and rat NADPH-P450 reductase.
    Shet MS, Fisher CW, Arlotto MP, Shackleton CH, Holmans PL, Martin-Wixtrom CA, Saeki Y, Estabrook RW.
    Arch Biochem Biophys; 1994 Jun 10; 311(2):402-17. PubMed ID: 8203904
    [Abstract] [Full Text] [Related]

  • 16. Influence of glutathione on the catalytic activity of reconstituted cytochrome P450 3A4.
    Kim BR, Kim DH.
    Biochem Biophys Res Commun; 1998 Jan 06; 242(1):209-12. PubMed ID: 9439637
    [Abstract] [Full Text] [Related]

  • 17. In vitro metabolism of terfenadine by a purified recombinant fusion protein containing cytochrome P4503A4 and NADPH-P450 reductase. Comparison to human liver microsomes and precision-cut liver tissue slices.
    Rodrigues AD, Mulford DJ, Lee RD, Surber BW, Kukulka MJ, Ferrero JL, Thomas SB, Shet MS, Estabrook RW.
    Drug Metab Dispos; 1995 Jul 06; 23(7):765-75. PubMed ID: 7587966
    [Abstract] [Full Text] [Related]

  • 18. Expression of cytochrome P450 3A7 in Escherichia coli: effects of 5' modification and catalytic characterization of recombinant enzyme expressed in bicistronic format with NADPH-cytochrome P450 reductase.
    Gillam EM, Wunsch RM, Ueng YF, Shimada T, Reilly PE, Kamataki T, Guengerich FP.
    Arch Biochem Biophys; 1997 Oct 01; 346(1):81-90. PubMed ID: 9328287
    [Abstract] [Full Text] [Related]

  • 19. Reconstitution of the enzymatic activities of cytochrome P450s using recombinant flavocytochromes containing rat cytochrome b(5) fused to NADPH--cytochrome P450 reductase with various membrane-binding segments.
    Gilep AA, Guryev OL, Usanov SA, Estabrook RW.
    Arch Biochem Biophys; 2001 Jun 15; 390(2):215-21. PubMed ID: 11396924
    [Abstract] [Full Text] [Related]

  • 20. Enhancement of cytochrome P-450 3A4 catalytic activities by cytochrome b(5) in bacterial membranes.
    Yamazaki H, Nakajima M, Nakamura M, Asahi S, Shimada N, Gillam EM, Guengerich FP, Shimada T, Yokoi T.
    Drug Metab Dispos; 1999 Sep 15; 27(9):999-1004. PubMed ID: 10460798
    [Abstract] [Full Text] [Related]

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