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Journal Abstract Search

195 related items for PubMed ID: 8292753

  • 1. Role of quinone methide in the in vitro toxicity of the skin tumor promoter butylated hydroxytoluene hydroperoxide.
    Guyton KZ, Thompson JA, Kensler TW.
    Chem Res Toxicol; 1993; 6(5):731-8. PubMed ID: 8292753
    [Abstract] [Full Text] [Related]

  • 2. Quinone methide mediates in vitro induction of ornithine decarboxylase by the tumor promoter butylated hydroxytoluene hydroperoxide.
    Guyton KZ, Dolan PM, Kensler TW.
    Carcinogenesis; 1994 May; 15(5):817-21. PubMed ID: 8200081
    [Abstract] [Full Text] [Related]

  • 3. Free radical-derived quinone methide mediates skin tumor promotion by butylated hydroxytoluene hydroperoxide: expanded role for electrophiles in multistage carcinogenesis.
    Guyton KZ, Bhan P, Kuppusamy P, Zweier JL, Trush MA, Kensler TW.
    Proc Natl Acad Sci U S A; 1991 Feb 01; 88(3):946-50. PubMed ID: 1846971
    [Abstract] [Full Text] [Related]

  • 4. Generation of reactive intermediates from the tumor promoter butylated hydroxytoluene hydroperoxide in isolated murine keratinocytes or by hematin.
    Taffe BG, Zweier JL, Pannell LK, Kensler TW.
    Carcinogenesis; 1989 Jul 01; 10(7):1261-8. PubMed ID: 2472232
    [Abstract] [Full Text] [Related]

  • 5. Tumor promotion by a hydroperoxide metabolite of butylated hydroxytoluene, 2,6-di-tert-butyl-4-hydroperoxy-4-methyl-2,5-cyclohexadienone, in mouse skin.
    Taffe BG, Kensler TW.
    Res Commun Chem Pathol Pharmacol; 1988 Sep 01; 61(3):291-303. PubMed ID: 3141995
    [Abstract] [Full Text] [Related]

  • 6. Lung toxicity and tumor promotion by hydroxylated derivatives of 2,6-di-tert-butyl-4-methylphenol (BHT) and 2-tert-butyl-4-methyl-6-iso-propylphenol: correlation with quinone methide reactivity.
    Kupfer R, Dwyer-Nield LD, Malkinson AM, Thompson JA.
    Chem Res Toxicol; 2002 Aug 01; 15(8):1106-12. PubMed ID: 12184795
    [Abstract] [Full Text] [Related]

  • 7. Studies using structural analogs and inbred strain differences to support a role for quinone methide metabolites of butylated hydroxytoluene (BHT) in mouse lung tumor promotion.
    Thompson JA, Carlson TJ, Sun Y, Dwyer-Nield LD, Malkinson AM.
    Toxicology; 2001 Mar 07; 160(1-3):197-205. PubMed ID: 11246140
    [Abstract] [Full Text] [Related]

  • 8. Mitogen-activated protein kinase (MAPK) activation by butylated hydroxytoluene hydroperoxide: implications for cellular survival and tumor promotion.
    Guyton KZ, Gorospe M, Kensler TW, Holbrook NJ.
    Cancer Res; 1996 Aug 01; 56(15):3480-5. PubMed ID: 8758915
    [Abstract] [Full Text] [Related]

  • 9. Formation and reactivity of alternative quinone methides from butylated hydroxytoluene: possible explanation for species-specific pneumotoxicity.
    Bolton JL, Sevestre H, Ibe BO, Thompson JA.
    Chem Res Toxicol; 1990 Aug 01; 3(1):65-70. PubMed ID: 2131827
    [Abstract] [Full Text] [Related]

  • 10. Electronic and structural requirements for metabolic activation of butylated hydroxytoluene analogs to their quinone methides, intermediates responsible for lung toxicity in mice.
    Yamamoto K, Kato S, Tajima K, Mizutani T.
    Biol Pharm Bull; 1997 May 01; 20(5):571-3. PubMed ID: 9178942
    [Abstract] [Full Text] [Related]

  • 11. Isotope effects on the metabolism and pulmonary toxicity of butylated hydroxytoluene in mice by deuteration of the 4-methyl group.
    Mizutani T, Yamamoto K, Tajima K.
    Toxicol Appl Pharmacol; 1983 Jun 30; 69(2):283-90. PubMed ID: 6868090
    [Abstract] [Full Text] [Related]

  • 12. Oxidation of butylated hydroxytoluene to toxic metabolites. Factors influencing hydroxylation and quinone methide formation by hepatic and pulmonary microsomes.
    Bolton JL, Thompson JA.
    Drug Metab Dispos; 1991 Jun 30; 19(2):467-72. PubMed ID: 1676656
    [Abstract] [Full Text] [Related]

  • 13. Immunochemical and proteomic analysis of covalent adducts formed by quinone methide tumor promoters in mouse lung epithelial cell lines.
    Meier BW, Gomez JD, Zhou A, Thompson JA.
    Chem Res Toxicol; 2005 Oct 30; 18(10):1575-85. PubMed ID: 16533022
    [Abstract] [Full Text] [Related]

  • 14. Relationship between the metabolism of butylated hydroxytoluene (BHT) and lung tumor promotion in mice.
    Thompson JA, Bolton JL, Malkinson AM.
    Exp Lung Res; 1991 Oct 30; 17(2):439-53. PubMed ID: 2050043
    [Abstract] [Full Text] [Related]

  • 15. The enzymatic formation and chemical reactivity of quinone methides correlate with alkylphenol-induced toxicity in rat hepatocytes.
    Bolton JL, Valerio LG, Thompson JA.
    Chem Res Toxicol; 1992 Oct 30; 5(6):816-22. PubMed ID: 1489934
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  • 18. Responses of tumorigenic and non-tumorigenic mouse lung epithelial cell lines to electrophilic metabolites of the tumor promoter butylated hydroxytoluene.
    Sun Y, Dwyer-Nield LD, Malkinson AM, Zhang YL, Thompson JA.
    Chem Biol Interact; 2003 Mar 06; 145(1):41-51. PubMed ID: 12606153
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  • 20. The role of 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone (BHT quinone methide) in the metabolism of butylated hydroxytoluene.
    Takahashi O, Hiraga K.
    Food Chem Toxicol; 1983 Jun 06; 21(3):279-83. PubMed ID: 6683224
    [Abstract] [Full Text] [Related]

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