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281 related items for PubMed ID: 8294879

  • 1. Evidence for differential intracellular signaling via CD4 and CD8 molecules.
    Ravichandran KS, Burakoff SJ.
    J Exp Med; 1994 Feb 01; 179(2):727-32. PubMed ID: 8294879
    [Abstract] [Full Text] [Related]

  • 2. Requirement for kinase activity of CD4-associated p56lck in antibody-triggered T cell signal transduction.
    Chu K, Littman DR.
    J Biol Chem; 1994 Sep 30; 269(39):24095-101. PubMed ID: 7929062
    [Abstract] [Full Text] [Related]

  • 3. CD3-zeta surface expression is required for CD4-p56lck-mediated upregulation of T cell antigen receptor-CD3 signaling in T cells.
    Sancho J, Ledbetter JA, Choi MS, Kanner SB, Deans JP, Terhorst C.
    J Biol Chem; 1992 Apr 15; 267(11):7871-9. PubMed ID: 1532798
    [Abstract] [Full Text] [Related]

  • 4. Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules.
    Wiest DL, Yuan L, Jefferson J, Benveniste P, Tsokos M, Klausner RD, Glimcher LH, Samelson LE, Singer A.
    J Exp Med; 1993 Nov 01; 178(5):1701-12. PubMed ID: 8228817
    [Abstract] [Full Text] [Related]

  • 5. CD8 beta chain influences CD8 alpha chain-associated Lck kinase activity.
    Irie HY, Ravichandran KS, Burakoff SJ.
    J Exp Med; 1995 Apr 01; 181(4):1267-73. PubMed ID: 7699318
    [Abstract] [Full Text] [Related]

  • 6. Galectin-1 specifically modulates TCR signals to enhance TCR apoptosis but inhibit IL-2 production and proliferation.
    Vespa GN, Lewis LA, Kozak KR, Moran M, Nguyen JT, Baum LG, Miceli MC.
    J Immunol; 1999 Jan 15; 162(2):799-806. PubMed ID: 9916701
    [Abstract] [Full Text] [Related]

  • 7. TCR activation of ZAP70 is impaired in CD4+CD8+ thymocytes as a consequence of intrathymic interactions that diminish available p56lck.
    Wiest DL, Ashe JM, Abe R, Bolen JB, Singer A.
    Immunity; 1996 May 15; 4(5):495-504. PubMed ID: 8630734
    [Abstract] [Full Text] [Related]

  • 8. Molecular analysis of the interaction of p56lck with the CD4 and CD8 antigens.
    Rudd CE, Barber EK, Burgess KE, Hahn JY, Odysseos AD, Sy MS, Schlossman SF.
    Adv Exp Med Biol; 1991 May 15; 292():85-96. PubMed ID: 1835265
    [Abstract] [Full Text] [Related]

  • 9. Differential association of CD45 isoforms with CD4 and CD8 regulates the actions of specific pools of p56lck tyrosine kinase in T cell antigen receptor signal transduction.
    Dornan S, Sebestyen Z, Gamble J, Nagy P, Bodnar A, Alldridge L, Doe S, Holmes N, Goff LK, Beverley P, Szollosi J, Alexander DR.
    J Biol Chem; 2002 Jan 18; 277(3):1912-8. PubMed ID: 11694532
    [Abstract] [Full Text] [Related]

  • 10. The CD45 tyrosine phosphatase regulates specific pools of antigen receptor-associated p59fyn and CD4-associated p56lck tyrosine in human T-cells.
    Biffen M, McMichael-Phillips D, Larson T, Venkitaraman A, Alexander D.
    EMBO J; 1994 Apr 15; 13(8):1920-9. PubMed ID: 8168490
    [Abstract] [Full Text] [Related]

  • 11. CD4-mediated enhancement or inhibition of T cell activation does not require the CD4:p56lck association.
    Zerbib AC, Reske-Kunz AB, Lock P, Sékaly RP.
    J Exp Med; 1994 Jun 01; 179(6):1973-83. PubMed ID: 8195720
    [Abstract] [Full Text] [Related]

  • 12. CD5 acts as a tyrosine kinase substrate within a receptor complex comprising T-cell receptor zeta chain/CD3 and protein-tyrosine kinases p56lck and p59fyn.
    Burgess KE, Yamamoto M, Prasad KV, Rudd CE.
    Proc Natl Acad Sci U S A; 1992 Oct 01; 89(19):9311-5. PubMed ID: 1384049
    [Abstract] [Full Text] [Related]

  • 13. Tyrosine kinase activity of CD4-associated p56lck may not be required for CD4-dependent T-cell activation.
    Collins TL, Burakoff SJ.
    Proc Natl Acad Sci U S A; 1993 Dec 15; 90(24):11885-9. PubMed ID: 7505449
    [Abstract] [Full Text] [Related]

  • 14. Cross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation site.
    Luo KX, Sefton BM.
    Mol Cell Biol; 1990 Oct 15; 10(10):5305-13. PubMed ID: 2118992
    [Abstract] [Full Text] [Related]

  • 15. Human intestinal epithelial cell-induced CD8+ T cell activation is mediated through CD8 and the activation of CD8-associated p56lck.
    Li Y, Yio XY, Mayer L.
    J Exp Med; 1995 Oct 01; 182(4):1079-88. PubMed ID: 7561681
    [Abstract] [Full Text] [Related]

  • 16. Decreased signaling competence as a result of receptor overexpression: overexpression of CD4 reduces its ability to activate p56lck tyrosine kinase and to regulate T-cell antigen receptor expression in immature CD4+CD8+ thymocytes.
    Nakayama T, Wiest DL, Abraham KM, Munitz TI, Perlmutter RM, Singer A.
    Proc Natl Acad Sci U S A; 1993 Nov 15; 90(22):10534-8. PubMed ID: 7902564
    [Abstract] [Full Text] [Related]

  • 17. A kinase-independent function of Lck in potentiating antigen-specific T cell activation.
    Xu H, Littman DR.
    Cell; 1993 Aug 27; 74(4):633-43. PubMed ID: 8358792
    [Abstract] [Full Text] [Related]

  • 18. Positive and negative selection of thymocytes depends on Lck interaction with the CD4 and CD8 coreceptors.
    Trobridge PA, Forbush KA, Levin SD.
    J Immunol; 2001 Jan 15; 166(2):809-18. PubMed ID: 11145654
    [Abstract] [Full Text] [Related]

  • 19. Molecular associations between the T-lymphocyte antigen receptor complex and the surface antigens CD2, CD4, or CD8 and CD5.
    Beyers AD, Spruyt LL, Williams AF.
    Proc Natl Acad Sci U S A; 1992 Apr 01; 89(7):2945-9. PubMed ID: 1372996
    [Abstract] [Full Text] [Related]

  • 20. Intrathymic signalling in immature CD4+CD8+ thymocytes results in tyrosine phosphorylation of the T-cell receptor zeta chain.
    Nakayama T, Singer A, Hsi ED, Samelson LE.
    Nature; 1989 Oct 19; 341(6243):651-4. PubMed ID: 2477711
    [Abstract] [Full Text] [Related]

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