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223 related items for PubMed ID: 8297143

  • 1. In vitro antitumor activity of a new platinum complex, DWA2114R against human tumor cell lines.
    Akamatsu K, Saito H, Tsunenari T, Matsumoto T, Morikawa K, Koizumi M, Mitsui H, Koizumi K.
    Anticancer Res; 1993; 13(6A):2261-5. PubMed ID: 8297143
    [Abstract] [Full Text] [Related]

  • 2. Antitumor effects of three platinum complexes, (-)-(R)-2-aminomethylpyrrolidine(1,1-cyclobutanedicarboxylato)-platinum (II) monohydrate (DWA2114R), cis-diammine-(1,1-cyclobutanedicarboxylato)platinum(II) (CBDCA) and cis-diamminedichloroplatinum(II) (CDDP), in mice.
    Endo K, Akamatsu K, Matsumoto T, Morikawa K, Koizumi M, Mitsui H, Koizumi K.
    Anticancer Res; 1992; 12(1):49-58. PubMed ID: 1567181
    [Abstract] [Full Text] [Related]

  • 3. In vitro and in vivo antineoplastic activity of a new platinum antineoplastic agent, (R)-(-)-1,1-cyclobutanedicarboxylate (2-aminomethylpyrrolidine)-platinum (II) (DWA2114R) on freshly separated human tumor cells and human tumor xenografts transplanted in nude mice--a comparison with cis-diammine-dichloroplatinum (CDDP).
    Nio Y, Imai S, Shiraishi T, Tsubono M, Morimoto H, Tseng CC, Tobe T.
    Anticancer Res; 1991; 11(2):761-7. PubMed ID: 2064331
    [Abstract] [Full Text] [Related]

  • 4. [Effect of treatment schedule of an antitumor platinum complex, DWA2114R, on the antitumor activity].
    Endo K, Akamatsu K, Matsumoto T, Morikawa K, Koizumi M, Mitsui H, Koizumi K.
    Gan To Kagaku Ryoho; 1992 Feb; 19(2):223-8. PubMed ID: 1736834
    [Abstract] [Full Text] [Related]

  • 5. In vitro antitumor activity of a new platinum complex, cis-malonato [(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane] platinum (II) (SKI 2053R), against human lung and stomach cancer cell lines.
    Hong WS, Kim HT, Kim KH, Kim DK.
    Anticancer Res; 1995 Feb; 15(1):51-4. PubMed ID: 7733640
    [Abstract] [Full Text] [Related]

  • 6. [Combination therapy of a new platinum complex, DWA2114R with various antitumor agents against mouse tumors in vivo].
    Akamatsu K, Endo K, Tsunenari T, Matsumoto T, Kaiho S, Morikawa K, Koizumi M, Mitsui H, Koizumi K.
    Gan To Kagaku Ryoho; 1992 Feb; 19(2):229-35. PubMed ID: 1736835
    [Abstract] [Full Text] [Related]

  • 7. Toxicological and tumoricidal evaluations of a new platinum complex, (-)-(R)-2-aminomethylpyrrolidine(1,1-cyclobutanedicarboxylato+ ++)platinum( II) monohydrate, in rats.
    Akamatsu K, Endo K, Matsumoto T, Morikawa K, Koizumi M, Koizumi K, Mitsui H.
    Jpn J Cancer Res; 1991 Jun; 82(6):724-31. PubMed ID: 1906857
    [Abstract] [Full Text] [Related]

  • 8. Antitumor activity and cellular accumulation of a new platinum complex, (-)-(R)-2-aminomethylpyrrolidine(1,1-cyclobutanedicarboxylato)platinum( II) monohydrate, in cisplatin-sensitive and -resistant murine P388 leukemia cells.
    Kamisango K, Matsumoto T, Akamatsu K, Morikawa K, Tashiro T, Koizumi K.
    Jpn J Cancer Res; 1992 Mar; 83(3):304-11. PubMed ID: 1582895
    [Abstract] [Full Text] [Related]

  • 9. Platinum agents in the treatment of osteosarcoma: efficacy of cisplatin vs. carboplatin in human osteosarcoma cell lines.
    Robson H, Meyer S, Shalet SM, Anderson E, Roberts S, Eden OB.
    Med Pediatr Oncol; 2002 Dec; 39(6):573-80. PubMed ID: 12376980
    [Abstract] [Full Text] [Related]

  • 10. [Antitumor activity of a new platinum complex, (R)-(-)-2-aminomethylpyrrolidine (1, 1-cyclobutanedicarboxylato) platinum (II), against cisdiamminedichloroplatinum (II)-resistant murine leukemia cell line].
    Akamatsu K, Endo K, Matsumoto T, Kamisango K, Morikawa K, Koizumi M, Mitsui H, Koizumi K, Matsuno T.
    Gan To Kagaku Ryoho; 1990 Jan; 17(1):73-8. PubMed ID: 2404458
    [Abstract] [Full Text] [Related]

  • 11. [Antitumor activity of a new platinum complex (R)-(-)-2-aminomethylpyrrolidine (1,1-cyclobutane dicarboxylato) platinum (II) (DWA2114R) by its serial administration].
    Akamatsu K, Endo K, Matsumoto T, Kamisango K, Morikawa K, Koizumi M, Mitsui H, Koizumi K, Matsuno T.
    Gan To Kagaku Ryoho; 1989 May; 16(5):2039-43. PubMed ID: 2658840
    [Abstract] [Full Text] [Related]

  • 12. Establishment and characterization of acquired resistance to platinum anticancer drugs in human ovarian carcinoma cells.
    Misawa T, Kikkawa F, Maeda O, Obata NH, Higashide K, Suganuma N, Tomoda Y.
    Jpn J Cancer Res; 1995 Jan; 86(1):88-94. PubMed ID: 7737915
    [Abstract] [Full Text] [Related]

  • 13. [Flow cytometric analysis of the effect of DWA2114R on the cell cycle traverse of RPMI 8402 cells--comparison with CDDP].
    Takamoto S, Souma R.
    Gan To Kagaku Ryoho; 1992 Apr; 19(4):469-76. PubMed ID: 1558396
    [Abstract] [Full Text] [Related]

  • 14. In vitro antitumor mechanism of a new platinum complex, (-)-(R)-2-aminomethylpyrrolidine(1,1-cyclobutanedicarboxylato+ ++) platinum(II).
    Akamatsu K, Endo K, Matsumoto T, Morikawa K, Koizumi M, Mitsui H, Koizumi K.
    Anticancer Res; 1991 Apr; 11(1):151-5. PubMed ID: 2018348
    [Abstract] [Full Text] [Related]

  • 15. Antitumor activity against human tumor samples of cis-diamminedichloroplatinum(II) and analogues at equivalent in vitro myelotoxic concentrations.
    Fan D, Baker FL, Khokhar AR, Ajani JA, Tomasovic B, Newman RA, Brock WA, Tueni E, Spitzer G.
    Cancer Res; 1988 Jun 01; 48(11):3135-9. PubMed ID: 3365698
    [Abstract] [Full Text] [Related]

  • 16. Potent antitumour activity of (-)-(R)-2-aminomethylpyrrolidine (1,1-cyclobutanedicarboxylato)platinum(II) monohydrate (DWA2114R) against advanced L1210 leukaemia in mice.
    Akamatsu K, Endo K, Matsumoto T, Kamisango K, Morikawa K, Koizumi M, Koizumi K.
    Br J Cancer; 1992 Nov 01; 66(5):827-32. PubMed ID: 1419625
    [Abstract] [Full Text] [Related]

  • 17. Potentiation by interleukin 1 alpha of cisplatin and carboplatin antitumor activity: schedule-dependent and pharmacokinetic effects in the RIF-1 tumor model.
    Chang MJ, Yu WD, Reyno LM, Modzelewski RA, Egorin MJ, Erkmen K, Vlock DR, Furmanski P, Johnson CS.
    Cancer Res; 1994 Oct 15; 54(20):5380-6. PubMed ID: 7923169
    [Abstract] [Full Text] [Related]

  • 18. The interactions of (-)-(R)-2-aminomethylpyrrolidine (1,1-cyclobutanedicarboxylato)platinum(II) monohydrate (DWA2114R) and related compounds with deoxyribonucleic acid.
    Morikawa K, Matsumoto T, Matsuoka Y, Koizumi K.
    Chem Pharm Bull (Tokyo); 1992 Jan 15; 40(1):212-9. PubMed ID: 1576676
    [Abstract] [Full Text] [Related]

  • 19. In vitro cytotoxicity, pharmacokinetics and ex vivo pharmacodynamics of a new platinum compound, cis-malonato [(4R,5R-4,5-bis(aminomethyl)-1,3-dioxolane-2-spiro-1'-cyclopentane] platinum (II).
    Kim DK, Kim HT, Cho YB, Kim TS, Kim KH, Hong WS.
    Anticancer Res; 1996 Jan 15; 16(1):251-6. PubMed ID: 8615617
    [Abstract] [Full Text] [Related]

  • 20. A new anticancer platinum compound, (-)-(R)-2-aminomethyl-pyrrolidine(1,1-cyclobutanedicarboxylato) platinum(II): DNA interstrand crosslinking, repair and lethal effects in normal human, Fanconi's anaemia and xeroderma pigmentosum cells.
    Fujiwara Y, Nakamura M, Yokoo S.
    Br J Cancer; 1993 Jun 15; 67(6):1285-92. PubMed ID: 8512813
    [Abstract] [Full Text] [Related]

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