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PUBMED FOR HANDHELDS

Journal Abstract Search


177 related items for PubMed ID: 8304185

  • 1. Substituted-2-desamino-2-methyl-quinazolinones. A series of novel antitumour agents.
    Boyle FT, Matusiak ZS, Hughes LR, Slater AM, Stephens TC, Smith MN, Brown M, Kimbell R, Jackman AL.
    Adv Exp Med Biol; 1993; 338():585-8. PubMed ID: 8304185
    [No Abstract] [Full Text] [Related]

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  • 3. The duration of the inhibition of thymidylate synthase in intact L1210 cells exposed to two different classes of quinazoline analogues.
    Kimbell R, Jackman AL, Boyle FT, Hardcastle A, Aherne W.
    Adv Exp Med Biol; 1993; 338():597-600. PubMed ID: 8304189
    [No Abstract] [Full Text] [Related]

  • 4. A potent antitumour quinazoline inhibitor of thymidylate synthetase: synthesis, biological properties and therapeutic results in mice.
    Jones TR, Calvert AH, Jackman AL, Brown SJ, Jones M, Harrap KR.
    Eur J Cancer (1965); 1981 Jan; 17(1):11-9. PubMed ID: 7262141
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  • 5. Quinazoline antifolate thymidylate synthase inhibitors: gamma-linked L-D, D-D, and D-L dipeptide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583).
    Bavetsias V, Jackman AL, Kimbell R, Gibson W, Boyle FT, Bisset GM.
    J Med Chem; 1996 Jan 05; 39(1):73-85. PubMed ID: 8568829
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  • 6. Gamma-linked dipeptide analogues of 2-desamino-2-methyl-N10-propargyl-5,8- dideazafolate as antitumour agents.
    Jackman AL, Bisset GM, Jodrell DI, Gibson W, Kimbell R, Bavetsias V, Calvert AH, Harrap KR, Stephens TC, Smith MN.
    Adv Exp Med Biol; 1993 Jan 05; 338():579-84. PubMed ID: 8304184
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  • 8. Use of murine L5178Y lymphoma thymidine kinase mutants for in vitro and in vivo antitumour efficacy evaluation of novel thymidylate synthase inhibitors.
    Stephens TC, Smith MN, Waterman SE, McCloskey ML, Jackman AL, Boyle FT.
    Adv Exp Med Biol; 1993 Jan 05; 338():589-92. PubMed ID: 8304186
    [No Abstract] [Full Text] [Related]

  • 9. Quinazoline antifolate thymidylate synthase inhibitors: alkyl, substituted alkyl, and aryl substituents in the C2 position.
    Hughes LR, Jackman AL, Oldfield J, Smith RC, Burrows KD, Marsham PR, Bishop JA, Jones TR, O'Connor BM, Calvert AH.
    J Med Chem; 1990 Nov 05; 33(11):3060-7. PubMed ID: 2231606
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  • 10. The antitumour activity of ZD9331, a non-polyglutamatable quinazoline thymidylate synthase inhibitor.
    Jackman AL, Kimbell R, Brown M, Brunton L, Harrap KR, Wardleworth JM, Boyle FT.
    Adv Exp Med Biol; 1994 Nov 05; 370():185-8. PubMed ID: 7660886
    [No Abstract] [Full Text] [Related]

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  • 12. Comparison of the biological effects of selected 5,8-dideazafolate analogues with their 2-desamino counterparts.
    Hynes JB, Patil SA, Hagan RL, Cole A, Kohler W, Freisheim JH.
    J Med Chem; 1989 Apr 05; 32(4):852-6. PubMed ID: 2704031
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  • 14. Potent inhibition of thymidylate synthase by two series of nonclassical quinazolines.
    McNamara DJ, Berman EM, Fry DW, Werbel LM.
    J Med Chem; 1990 Jul 05; 33(7):2045-51. PubMed ID: 2362285
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  • 15. Quinazoline antifolate thymidylate synthase inhibitors: replacement of glutamic acid in the C2-methyl series.
    Marsham PR, Jackman AL, Barker AJ, Boyle FT, Pegg SJ, Wardleworth JM, Kimbell R, O'Connor BM, Calvert AH, Hughes LR.
    J Med Chem; 1995 Mar 17; 38(6):994-1004. PubMed ID: 7699716
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  • 16. Design and synthesis of Cyclopenta[g]quinazoline-based antifolates as inhibitors of thymidylate synthase and potential antitumor agents(,).
    Bavetsias V, Marriott JH, Melin C, Kimbell R, Matusiak ZS, Boyle FT, Jackman AL.
    J Med Chem; 2000 May 18; 43(10):1910-26. PubMed ID: 10821704
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  • 18. Estimation of the in vitro and in vivo inhibitory effects of antifolates upon thymidylate synthase (TS) in whole cells.
    Taylor GA, Jackman AL, Balmanno K, Hughes LR, Calvert AH.
    Adv Exp Med Biol; 1989 May 18; 253B():383-8. PubMed ID: 2610126
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