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343 related items for PubMed ID: 8316219

  • 1. Enzymatic and pH modulation of mitomycin C-induced DNA damage in mitomycin C-resistant HCT 116 human colon cancer cells.
    Pan SS, Yu F, Hipsher C.
    Mol Pharmacol; 1993 Jun; 43(6):870-7. PubMed ID: 8316219
    [Abstract] [Full Text] [Related]

  • 2. Effect of pH on DNA alkylation by enzyme-activated mitomycin C and porfiromycin.
    Yu F, Pan SS.
    Mol Pharmacol; 1993 Jun; 43(6):863-9. PubMed ID: 8391116
    [Abstract] [Full Text] [Related]

  • 3. NAD(P)H:quinone oxidoreductase expression and mitomycin C resistance developed by human colon cancer HCT 116 cells.
    Pan SS, Forrest GL, Akman SA, Hu LT.
    Cancer Res; 1995 Jan 15; 55(2):330-5. PubMed ID: 7812966
    [Abstract] [Full Text] [Related]

  • 4. The role of NAD(P)H:quinone oxidoreductase in mitomycin C- and porfiromycin-resistant HCT 116 human colon-cancer cells.
    Pan SS, Akman SA, Forrest GL, Hipsher C, Johnson R.
    Cancer Chemother Pharmacol; 1992 Jan 15; 31(1):23-31. PubMed ID: 1458556
    [Abstract] [Full Text] [Related]

  • 5. The NAD(P)H:quinone oxidoreductase locus in human colon carcinoma HCT 116 cells resistant to mitomycin C.
    Hu LT, Stamberg J, Pan S.
    Cancer Res; 1996 Nov 15; 56(22):5253-9. PubMed ID: 8912865
    [Abstract] [Full Text] [Related]

  • 6. Adducts of mitomycin C and DNA in EMT6 mouse mammary tumor cells: effects of hypoxia and dicumarol on adduct patterns.
    Bizanek R, Chowdary D, Arai H, Kasai M, Hughes CS, Sartorelli AC, Rockwell S, Tomasz M.
    Cancer Res; 1993 Nov 01; 53(21):5127-34. PubMed ID: 7693331
    [Abstract] [Full Text] [Related]

  • 7. Mitomycin C-DNA adducts generated by DT-diaphorase. Revised mechanism of the enzymatic reductive activation of mitomycin C.
    Suresh Kumar G, Lipman R, Cummings J, Tomasz M.
    Biochemistry; 1997 Nov 18; 36(46):14128-36. PubMed ID: 9369485
    [Abstract] [Full Text] [Related]

  • 8. DT-diaphorase as a target enzyme for biochemical modulation of mitomycin C.
    Saeki S, Nishiyama M, Toge T.
    Hiroshima J Med Sci; 1995 Sep 18; 44(3):55-63. PubMed ID: 8567314
    [Abstract] [Full Text] [Related]

  • 9. Tumor-specific synergistic therapy of mitomycin C: modulation of bioreductive activation.
    Sakamoto N, Toge T, Nishiyama M.
    Hiroshima J Med Sci; 1997 Jun 18; 46(2):67-73. PubMed ID: 9232934
    [Abstract] [Full Text] [Related]

  • 10. DT-diaphorase as a critical determinant of sensitivity to mitomycin C in human colon and gastric carcinoma cell lines.
    Mikami K, Naito M, Tomida A, Yamada M, Sirakusa T, Tsuruo T.
    Cancer Res; 1996 Jun 15; 56(12):2823-6. PubMed ID: 8665520
    [Abstract] [Full Text] [Related]

  • 11. NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.
    Traver RD, Horikoshi T, Danenberg KD, Stadlbauer TH, Danenberg PV, Ross D, Gibson NW.
    Cancer Res; 1992 Feb 15; 52(4):797-802. PubMed ID: 1737339
    [Abstract] [Full Text] [Related]

  • 12. Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells.
    Siegel D, Gibson NW, Preusch PC, Ross D.
    Cancer Res; 1990 Dec 01; 50(23):7483-9. PubMed ID: 1701346
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  • 17. [Mitomycin C and its bioreduction: relevance of NAD(P)H: quinone oxidoreductase activity to mitomycin C-induced DNA damage and cytotoxicity].
    Nishiyama M, Saeki S, Aogi K, Hirabayashi N, Toge T.
    Gan To Kagaku Ryoho; 1993 Jun 01; 20(8):1037-41. PubMed ID: 7685584
    [Abstract] [Full Text] [Related]

  • 18. [Mechanism of resistance to mitomycin C in a human bladder cancer cell line].
    Xu B, Sun Y, Singh SV.
    Zhonghua Zhong Liu Za Zhi; 1995 Sep 01; 17(5):343-6. PubMed ID: 8697971
    [Abstract] [Full Text] [Related]

  • 19. Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases.
    Beall HD, Mulcahy RT, Siegel D, Traver RD, Gibson NW, Ross D.
    Cancer Res; 1994 Jun 15; 54(12):3196-201. PubMed ID: 8205540
    [Abstract] [Full Text] [Related]

  • 20. Nonenzymatic reductive activation of 7-N-((2-([2-(gamma-L-glutamylamino)ethyl]dithio)ethyl))mitomycin C by thiol molecules: a novel mitomycin C derivative effective on mitomycin C-resistant tumor cells.
    Lee JH, Naito M, Tsuruo T.
    Cancer Res; 1994 May 01; 54(9):2398-403. PubMed ID: 8162587
    [Abstract] [Full Text] [Related]

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