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Journal Abstract Search


498 related items for PubMed ID: 8324738

  • 21. Inhibition of tobacco-specific nitrosamine 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK) tumorigenesis with aromatic isothiocyanates.
    Morse MA, Eklind KI, Hecht SS, Chung FL.
    IARC Sci Publ; 1991; (105):529-34. PubMed ID: 1855911
    [Abstract] [Full Text] [Related]

  • 22. Effect of dietary aromatic isothiocyanates fed subsequent to the administration of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone on lung tumorigenicity in mice.
    Morse MA, Reinhardt JC, Amin SG, Hecht SS, Stoner GD, Chung FL.
    Cancer Lett; 1990 Mar; 49(3):225-30. PubMed ID: 2317784
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  • 25. Kinetics and enzyme involvement in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in microsomes of rat lung and nasal mucosa.
    Smith TJ, Guo Z, Hong JY, Ning SM, Thomas PE, Yang CS.
    Carcinogenesis; 1992 Aug; 13(8):1409-14. PubMed ID: 1499091
    [Abstract] [Full Text] [Related]

  • 26. Effect of phenethyl isothiocyanate on the metabolism of tobacco-specific nitrosamines by cultured rat oral tissue.
    Murphy SE, Heiblum R, King PG, Bowman D, Davis WJ, Stoner GD.
    Carcinogenesis; 1991 Jun; 12(6):957-61. PubMed ID: 2044202
    [Abstract] [Full Text] [Related]

  • 27. Effect of tobacco smoke condensate on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by adult and fetal hamster microsomes.
    Jorquera R, Castonguay A, Schuller HM.
    Drug Metab Dispos; 1993 Jun; 21(2):318-24. PubMed ID: 8097703
    [Abstract] [Full Text] [Related]

  • 28. Effects of pregnancy and ethanol treatment on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by hamster liver and lung microsomes.
    Jorquera R, Castonguay A, Schuller HM.
    Drug Metab Dispos; 1992 Jun; 20(4):510-7. PubMed ID: 1356727
    [Abstract] [Full Text] [Related]

  • 29. 11Beta-hydroxysteroid dehydrogenase responsible for carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes.
    Maser E.
    Cancer Res; 1998 Jul 15; 58(14):2996-3003. PubMed ID: 9679962
    [Abstract] [Full Text] [Related]

  • 30. Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in peripheral human lung microsomes.
    Smith GB, Bend JR, Bedard LL, Reid KR, Petsikas D, Massey TE.
    Drug Metab Dispos; 2003 Sep 15; 31(9):1134-41. PubMed ID: 12920169
    [Abstract] [Full Text] [Related]

  • 31. Effects of watercress consumption on metabolism of a tobacco-specific lung carcinogen in smokers.
    Hecht SS, Chung FL, Richie JP, Akerkar SA, Borukhova A, Skowronski L, Carmella SG.
    Cancer Epidemiol Biomarkers Prev; 1995 Dec 15; 4(8):877-84. PubMed ID: 8634661
    [Abstract] [Full Text] [Related]

  • 32. Effects of dietary indoles and isothiocyanates on N-nitrosodimethylamine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone alpha-hydroxylation and DNA methylation in rat liver.
    Chung FL, Wang MY, Hecht SS.
    Carcinogenesis; 1985 Apr 15; 6(4):539-43. PubMed ID: 3986960
    [Abstract] [Full Text] [Related]

  • 33. Effects of citrus phytochemicals on liver and lung cytochrome P450 activity and on the in vitro metabolism of the tobacco-specific nitrosamine NNK.
    Bear WL, Teel RW.
    Anticancer Res; 2000 Apr 15; 20(5A):3323-9. PubMed ID: 11062760
    [Abstract] [Full Text] [Related]

  • 34. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human placental microsomes.
    Collazo NR, Sultatos LG.
    Biochem Pharmacol; 1995 Nov 27; 50(11):1933-41. PubMed ID: 8615875
    [Abstract] [Full Text] [Related]

  • 35. Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone pulmonary metabolism and tumorigenicity in mice by analogues of the investigational chemotherapeutic drug 4-ipomeanol.
    Lin JM, Desai DH, Morse MA, Amin S, Hecht SS.
    Chem Res Toxicol; 1992 Nov 27; 5(5):674-9. PubMed ID: 1446008
    [Abstract] [Full Text] [Related]

  • 36. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific carcinogen, by rabbit nasal microsomes and cytochrome P450s NMa and NMb.
    Hong JY, Ding X, Smith TJ, Coon MJ, Yang CS.
    Carcinogenesis; 1992 Nov 27; 13(11):2141-4. PubMed ID: 1423886
    [Abstract] [Full Text] [Related]

  • 37. A principal mechanism for the cancer chemopreventive activity of phenethyl isothiocyanate is modulation of carcinogen metabolism.
    Ioannides C, Konsue N.
    Drug Metab Rev; 2015 Aug 27; 47(3):356-73. PubMed ID: 26119477
    [Abstract] [Full Text] [Related]

  • 38. Chemopreventive efficacy of arylalkyl isothiocyanates and N-acetylcysteine for lung tumorigenesis in Fischer rats.
    Chung FL, Kelloff G, Steele V, Pittman B, Zang E, Jiao D, Rigotty J, Choi CI, Rivenson A.
    Cancer Res; 1996 Feb 15; 56(4):772-8. PubMed ID: 8631012
    [Abstract] [Full Text] [Related]

  • 39. Comparative metabolism of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol by rat cytochrome P450 2A3 and human cytochrome P450 2A13.
    Jalas JR, Ding X, Murphy SE.
    Drug Metab Dispos; 2003 Oct 15; 31(10):1199-202. PubMed ID: 12975327
    [Abstract] [Full Text] [Related]

  • 40. Quantitation of microsomal alpha-hydroxylation of the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Peterson LA, Mathew R, Hecht SS.
    Cancer Res; 1991 Oct 15; 51(20):5495-500. PubMed ID: 1913670
    [Abstract] [Full Text] [Related]


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