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759 related items for PubMed ID: 8325965

  • 1. Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase.
    Swart P, Swart AC, Waterman MR, Estabrook RW, Mason JI.
    J Clin Endocrinol Metab; 1993 Jul; 77(1):98-102. PubMed ID: 8325965
    [Abstract] [Full Text] [Related]

  • 2. Steroid 17 alpha-hydroxylase and 17,20-lyase activities of P450c17: contributions of serine106 and P450 reductase.
    Lin D, Black SM, Nagahama Y, Miller WL.
    Endocrinology; 1993 Jun; 132(6):2498-506. PubMed ID: 8504753
    [Abstract] [Full Text] [Related]

  • 3. Characterization of the adrenal cytochrome P450C17 in the hamster, a small animal model for the study of adrenal dehydroepiandrosterone biosynthesis.
    Cloutier M, Fleury A, Courtemanche J, Ducharme L, Mason JI, Lehoux JG.
    DNA Cell Biol; 1997 Mar; 16(3):357-68. PubMed ID: 9115645
    [Abstract] [Full Text] [Related]

  • 4. The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway.
    Flück CE, Miller WL, Auchus RJ.
    J Clin Endocrinol Metab; 2003 Aug; 88(8):3762-6. PubMed ID: 12915666
    [Abstract] [Full Text] [Related]

  • 5. Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.
    Yamazaki H, Shimada T.
    Arch Biochem Biophys; 1997 Oct 01; 346(1):161-9. PubMed ID: 9328296
    [Abstract] [Full Text] [Related]

  • 6. The role of cytochrome b5 in the biosynthesis of androgens by human P450c17.
    Katagiri M, Kagawa N, Waterman MR.
    Arch Biochem Biophys; 1995 Mar 10; 317(2):343-7. PubMed ID: 7893148
    [Abstract] [Full Text] [Related]

  • 7. Ketoconazole inhibition of the bifunctional cytochrome P450c17 does not affect androgen formation from the endogenous lyase substrate. The catalytic site remains refractory in the course of intermediary hydroxyprogesterone processing.
    Kühn-Velten WN, Lessmann M.
    Biochem Pharmacol; 1992 Dec 15; 44(12):2371-8. PubMed ID: 1472102
    [Abstract] [Full Text] [Related]

  • 8. Expression of bovine 17 alpha-hydroxylase cytochrome P-450 cDNA in nonsteroidogenic (COS 1) cells.
    Zuber MX, Simpson ER, Waterman MR.
    Science; 1986 Dec 05; 234(4781):1258-61. PubMed ID: 3535074
    [Abstract] [Full Text] [Related]

  • 9. Progesterone metabolism in hepatic microsomes. Effect of the cytochrome P-450 inhibitor, ketoconazole, and the NADPH 5 alpha-reductase inhibitor, 4-MA, upon the metabolic profile in human, monkey, dog, and rat.
    Swinney DC.
    Drug Metab Dispos; 1990 Dec 05; 18(6):859-65. PubMed ID: 1981529
    [Abstract] [Full Text] [Related]

  • 10. Simultaneous transfection of COS-1 cells with mitochondrial and microsomal steroid hydroxylases: incorporation of a steroidogenic pathway into nonsteroidogenic cells.
    Zuber MX, Mason JI, Simpson ER, Waterman MR.
    Proc Natl Acad Sci U S A; 1988 Feb 05; 85(3):699-703. PubMed ID: 2829199
    [Abstract] [Full Text] [Related]

  • 11. Regulation of cholesterol side-chain cleavage and 17 alpha-hydroxylase/lyase activities in proliferating human theca interna cells in long term monolayer culture.
    McAllister JM, Kerin JF, Trant JM, Estabrook RW, Mason JI, Waterman MR, Simpson ER.
    Endocrinology; 1989 Oct 05; 125(4):1959-66. PubMed ID: 2676474
    [Abstract] [Full Text] [Related]

  • 12. The lithocholic acid 6 beta-hydroxylase cytochrome P-450, CYP 3A10, is an active catalyst of steroid-hormone 6 beta-hydroxylation.
    Chang TK, Teixeira J, Gil G, Waxman DJ.
    Biochem J; 1993 Apr 15; 291 ( Pt 2)(Pt 2):429-33. PubMed ID: 8484723
    [Abstract] [Full Text] [Related]

  • 13. Ovine steroid 17alpha-hydroxylase cytochrome P450: characteristics of the hydroxylase and lyase activities of the adrenal cortex enzyme.
    Swart P, Lombard N, Swart AC, van der Merwe T, Murry BA, Nicol M, Ian Mason J.
    Arch Biochem Biophys; 2003 Jan 01; 409(1):145-52. PubMed ID: 12464253
    [Abstract] [Full Text] [Related]

  • 14. A single amino acid residue, Ala 105, confers 16alpha-hydroxylase activity to human cytochrome P450 17alpha-hydroxylase/17,20 lyase.
    Swart AC, Storbeck KH, Swart P.
    J Steroid Biochem Mol Biol; 2010 Apr 01; 119(3-5):112-20. PubMed ID: 20043997
    [Abstract] [Full Text] [Related]

  • 15. Kinetic control of steroidogenesis by steroid concentration in guinea pig adrenal microsomes.
    Higuchi A, Kominami S, Takemori S.
    Biochim Biophys Acta; 1991 Jul 30; 1084(3):240-6. PubMed ID: 1888770
    [Abstract] [Full Text] [Related]

  • 16. Role of electron transport in the regulation of the lyase activity of C21 side-chain cleavage P-450 from porcine adrenal and testicular microsomes.
    Yanagibashi K, Hall PF.
    J Biol Chem; 1986 Jun 25; 261(18):8429-33. PubMed ID: 3487544
    [Abstract] [Full Text] [Related]

  • 17. In vitro effect of 16alpha-hydroxyprogesterone on the enzyme activities related to androgen production in human testes.
    Inano H, Tamaoki B.
    Acta Endocrinol (Copenh); 1978 Aug 25; 88(4):768-77. PubMed ID: 581117
    [Abstract] [Full Text] [Related]

  • 18. Modulation of 17alpha-hydroxylase/17,20-lyase activity of guinea pig cytochrome P450c17 by site-directed mutagenesis.
    Beaudoin C, Lavallée B, Tremblay Y, Hum DW, Breton R, de Launoit Y, Bélanger A.
    DNA Cell Biol; 1998 Aug 25; 17(8):707-15. PubMed ID: 9726253
    [Abstract] [Full Text] [Related]

  • 19. CYP17A1 exhibits 17αhydroxylase/17,20-lyase activity towards 11β-hydroxyprogesterone and 11-ketoprogesterone metabolites in the C11-oxy backdoor pathway.
    van Rooyen D, Yadav R, Scott EE, Swart AC.
    J Steroid Biochem Mol Biol; 2020 May 25; 199():105614. PubMed ID: 32007561
    [Abstract] [Full Text] [Related]

  • 20. The function of recombinant cytochrome P450s in intact Escherichia coli cells: the 17 alpha-hydroxylation of progesterone and pregnenolone by P450c17.
    Shet MS, Fisher CW, Estabrook RW.
    Arch Biochem Biophys; 1997 Mar 01; 339(1):218-25. PubMed ID: 9056252
    [Abstract] [Full Text] [Related]

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