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Journal Abstract Search

306 related items for PubMed ID: 8326017

  • 1. Inhibition of Ca(2+)-dependent K+ transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives.
    Brugnara C, de Franceschi L, Alper SL.
    J Clin Invest; 1993 Jul; 92(1):520-6. PubMed ID: 8326017
    [Abstract] [Full Text] [Related]

  • 2.
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  • 3. Treatment with oral clotrimazole blocks Ca(2+)-activated K+ transport and reverses erythrocyte dehydration in transgenic SAD mice. A model for therapy of sickle cell disease.
    De Franceschi L, Saadane N, Trudel M, Alper SL, Brugnara C, Beuzard Y.
    J Clin Invest; 1994 Apr; 93(4):1670-6. PubMed ID: 7512989
    [Abstract] [Full Text] [Related]

  • 4. Therapeutic strategies for prevention of sickle cell dehydration.
    Brugnara C.
    Blood Cells Mol Dis; 2001 Apr; 27(1):71-80. PubMed ID: 11358364
    [Abstract] [Full Text] [Related]

  • 5. Effect of 1-chloro-2,4-dinitrobenzene on K+ transport in normal and sickle human red blood cells.
    Muzyamba MC, Gibson JS.
    J Physiol; 2003 Mar 15; 547(Pt 3):903-11. PubMed ID: 12576491
    [Abstract] [Full Text] [Related]

  • 6. The antifungal antibiotic, clotrimazole, inhibits Cl- secretion by polarized monolayers of human colonic epithelial cells.
    Rufo PA, Jiang L, Moe SJ, Brugnara C, Alper SL, Lencer WI.
    J Clin Invest; 1996 Nov 01; 98(9):2066-75. PubMed ID: 8903326
    [Abstract] [Full Text] [Related]

  • 7. ICA-17043, a novel Gardos channel blocker, prevents sickled red blood cell dehydration in vitro and in vivo in SAD mice.
    Stocker JW, De Franceschi L, McNaughton-Smith GA, Corrocher R, Beuzard Y, Brugnara C.
    Blood; 2003 Mar 15; 101(6):2412-8. PubMed ID: 12433690
    [Abstract] [Full Text] [Related]

  • 8. Novel inhibitors of the Gardos channel for the treatment of sickle cell disease.
    McNaughton-Smith GA, Burns JF, Stocker JW, Rigdon GC, Creech C, Arrington S, Shelton T, de Franceschi L.
    J Med Chem; 2008 Feb 28; 51(4):976-82. PubMed ID: 18232633
    [Abstract] [Full Text] [Related]

  • 9. Prevention of red cell dehydration: a possible new treatment for sickle cell disease.
    Mueller BU, Brugnara C.
    Pediatr Pathol Mol Med; 2001 Feb 28; 20(1):15-25. PubMed ID: 12673842
    [Abstract] [Full Text] [Related]

  • 10. Membrane transport of Na and K and cell dehydration in sickle erythrocytes.
    Brugnara C.
    Experientia; 1993 Feb 15; 49(2):100-9. PubMed ID: 8440348
    [Abstract] [Full Text] [Related]

  • 11. Abnormal permeability pathways in human red blood cells.
    Ellory JC, Robinson HC, Browning JA, Stewart GW, Gehl KA, Gibson JS.
    Blood Cells Mol Dis; 2007 Feb 15; 39(1):1-6. PubMed ID: 17434766
    [Abstract] [Full Text] [Related]

  • 12. Therapy with oral clotrimazole induces inhibition of the Gardos channel and reduction of erythrocyte dehydration in patients with sickle cell disease.
    Brugnara C, Gee B, Armsby CC, Kurth S, Sakamoto M, Rifai N, Alper SL, Platt OS.
    J Clin Invest; 1996 Mar 01; 97(5):1227-34. PubMed ID: 8636434
    [Abstract] [Full Text] [Related]

  • 13. The antifungal imidazole clotrimazole and its major in vivo metabolite are potent blockers of the calcium-activated potassium channel in murine erythroleukemia cells.
    Rittenhouse AR, Vandorpe DH, Brugnara C, Alper SL.
    J Membr Biol; 1997 May 15; 157(2):177-91. PubMed ID: 9151659
    [Abstract] [Full Text] [Related]

  • 14. Red cell volume-related ion transport systems in hemoglobinopathies.
    Canessa M.
    Hematol Oncol Clin North Am; 1991 Jun 15; 5(3):495-516. PubMed ID: 1650770
    [Abstract] [Full Text] [Related]

  • 15. N-acetylcysteine and clotrimazole inhibit sickle erythrocyte dehydration induced by 1-chloro-2,4-dinitrobenzene.
    Shartava A, Shah AK, Goodman SR.
    Am J Hematol; 1999 Sep 15; 62(1):19-24. PubMed ID: 10467272
    [Abstract] [Full Text] [Related]

  • 16. [Clinical trials of new therapeutic pharmacology for sickle cell disease].
    Brugnara C, de Franceschi L.
    Sante; 2006 Sep 15; 16(4):263-8. PubMed ID: 17446160
    [Abstract] [Full Text] [Related]

  • 17. Dehydration response of sickle cells to sickling-induced Ca(++) permeabilization.
    Lew VL, Etzion Z, Bookchin RM.
    Blood; 2002 Apr 01; 99(7):2578-85. PubMed ID: 11895796
    [Abstract] [Full Text] [Related]

  • 18. The feasibility of pharmacological volume control of sickle cells is dependent on the quantization of the transport pathways. A model study.
    Bennekou P.
    J Theor Biol; 1999 Jan 07; 196(1):129-37. PubMed ID: 9892561
    [Abstract] [Full Text] [Related]

  • 19. Erythrocyte dehydration in pathophysiology and treatment of sickle cell disease.
    Brugnara C.
    Curr Opin Hematol; 1995 Mar 07; 2(2):132-8. PubMed ID: 9371983
    [Abstract] [Full Text] [Related]

  • 20. The effect of abnormal hemoglobins on the membrane regulation of cell hydration.
    Clark MR, Shohet SB.
    Tex Rep Biol Med; 1995 Mar 07; 40():417-29. PubMed ID: 7034277
    [Abstract] [Full Text] [Related]

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