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Journal Abstract Search

173 related items for PubMed ID: 8340361

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  • 3. Mutations which impede loop/sheet polymerization enhance the secretion of human alpha 1-antitrypsin deficiency variants.
    Sidhar SK, Lomas DA, Carrell RW, Foreman RC.
    J Biol Chem; 1995 Apr 14; 270(15):8393-6. PubMed ID: 7721731
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  • 4. Loop-sheet polymerization: the structural basis of Z alpha 1-antitrypsin accumulation in the liver.
    Lomas DA.
    Clin Sci (Lond); 1994 May 14; 86(5):489-95. PubMed ID: 8033502
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  • 5. Differential detection of PAS-positive inclusions formed by the Z, Siiyama, and Mmalton variants of alpha1-antitrypsin.
    Janciauskiene S, Eriksson S, Callea F, Mallya M, Zhou A, Seyama K, Hata S, Lomas DA.
    Hepatology; 2004 Nov 14; 40(5):1203-10. PubMed ID: 15486938
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  • 9. Conformational changes in serpins and the mechanism of alpha 1-antitrypsin deficiency.
    Carrell RW, Whisstock J, Lomas DA.
    Am J Respir Crit Care Med; 1994 Dec 14; 150(6 Pt 2):S171-5. PubMed ID: 7952655
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  • 11. A protein structural approach to the solution of biological problems: alpha 1-antitrypsin as a recent example.
    Lomas DA, Carrell RW.
    Am J Physiol; 1993 Sep 14; 265(3 Pt 1):L211-9. PubMed ID: 8214081
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  • 13. Loop-sheet mechanism of serpin polymerization tested by reactive center loop mutations.
    Yamasaki M, Sendall TJ, Harris LE, Lewis GM, Huntington JA.
    J Biol Chem; 2010 Oct 01; 285(40):30752-8. PubMed ID: 20667823
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  • 14. Alpha 1-antitrypsin-deficient variant Siiyama (Ser53[TCC] to Phe53[TTC]) is prevalent in Japan. Status of alpha 1-antitrypsin deficiency in Japan.
    Seyama K, Nukiwa T, Souma S, Shimizu K, Kira S.
    Am J Respir Crit Care Med; 1995 Dec 01; 152(6 Pt 1):2119-26. PubMed ID: 8520784
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  • 15. New insights into the structural basis of alpha 1-antitrypsin deficiency.
    Lomas DA.
    QJM; 1996 Nov 01; 89(11):807-12. PubMed ID: 8977959
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  • 17. 6-mer peptide selectively anneals to a pathogenic serpin conformation and blocks polymerization. Implications for the prevention of Z alpha(1)-antitrypsin-related cirrhosis.
    Mahadeva R, Dafforn TR, Carrell RW, Lomas DA.
    J Biol Chem; 2002 Mar 01; 277(9):6771-4. PubMed ID: 11773044
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  • 20. Defining the mechanism of polymerization in the serpinopathies.
    Ekeowa UI, Freeke J, Miranda E, Gooptu B, Bush MF, Pérez J, Teckman J, Robinson CV, Lomas DA.
    Proc Natl Acad Sci U S A; 2010 Oct 05; 107(40):17146-51. PubMed ID: 20855577
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