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213 related items for PubMed ID: 8347619

  • 1. Real-time measurements of kinetics of EGF binding to soluble EGF receptor monomers and dimers support the dimerization model for receptor activation.
    Zhou M, Felder S, Rubinstein M, Hurwitz DR, Ullrich A, Lax I, Schlessinger J.
    Biochemistry; 1993 Aug 17; 32(32):8193-8. PubMed ID: 8347619
    [Abstract] [Full Text] [Related]

  • 2. Ligand-binding enhances the affinity of dimerization of the extracellular domain of the epidermal growth factor receptor.
    Odaka M, Kohda D, Lax I, Schlessinger J, Inagaki F.
    J Biochem; 1997 Jul 17; 122(1):116-21. PubMed ID: 9276679
    [Abstract] [Full Text] [Related]

  • 3. Two EGF molecules contribute additively to stabilization of the EGFR dimer.
    Lemmon MA, Bu Z, Ladbury JE, Zhou M, Pinchasi D, Lax I, Engelman DM, Schlessinger J.
    EMBO J; 1997 Jan 15; 16(2):281-94. PubMed ID: 9029149
    [Abstract] [Full Text] [Related]

  • 4. Stoichiometry, kinetic and binding analysis of the interaction between epidermal growth factor (EGF) and the extracellular domain of the EGF receptor.
    Domagala T, Konstantopoulos N, Smyth F, Jorissen RN, Fabri L, Geleick D, Lax I, Schlessinger J, Sawyer W, Howlett GJ, Burgess AW, Nice EC.
    Growth Factors; 2000 Jan 15; 18(1):11-29. PubMed ID: 10831070
    [Abstract] [Full Text] [Related]

  • 5. EGF induces increased ligand binding affinity and dimerization of soluble epidermal growth factor (EGF) receptor extracellular domain.
    Hurwitz DR, Emanuel SL, Nathan MH, Sarver N, Ullrich A, Felder S, Lax I, Schlessinger J.
    J Biol Chem; 1991 Nov 15; 266(32):22035-43. PubMed ID: 1657987
    [Abstract] [Full Text] [Related]

  • 6. The extracellular domain of the epidermal growth factor receptor. Studies on the affinity and stoichiometry of binding, receptor dimerization and a binding-domain mutant.
    Brown PM, Debanne MT, Grothe S, Bergsma D, Caron M, Kay C, O'Connor-McCourt MD.
    Eur J Biochem; 1994 Oct 01; 225(1):223-33. PubMed ID: 7925442
    [Abstract] [Full Text] [Related]

  • 7. EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization.
    Ferguson KM, Berger MB, Mendrola JM, Cho HS, Leahy DJ, Lemmon MA.
    Mol Cell; 2003 Feb 01; 11(2):507-17. PubMed ID: 12620237
    [Abstract] [Full Text] [Related]

  • 8. A 40-kDa epidermal growth factor/transforming growth factor alpha-binding domain produced by limited proteolysis of the extracellular domain of the epidermal growth factor receptor.
    Kohda D, Odaka M, Lax I, Kawasaki H, Suzuki K, Ullrich A, Schlessinger J, Inagaki F.
    J Biol Chem; 1993 Jan 25; 268(3):1976-81. PubMed ID: 8420971
    [Abstract] [Full Text] [Related]

  • 9. Epidermal growth factor (EGF) induces oligomerization of soluble, extracellular, ligand-binding domain of EGF receptor. A low resolution projection structure of the ligand-binding domain.
    Lax I, Mitra AK, Ravera C, Hurwitz DR, Rubinstein M, Ullrich A, Stroud RM, Schlessinger J.
    J Biol Chem; 1991 Jul 25; 266(21):13828-33. PubMed ID: 1856216
    [Abstract] [Full Text] [Related]

  • 10. Stabilization of an active dimeric form of the epidermal growth factor receptor by introduction of an inter-receptor disulfide bond.
    Sorokin A, Lemmon MA, Ullrich A, Schlessinger J.
    J Biol Chem; 1994 Apr 01; 269(13):9752-9. PubMed ID: 8144568
    [Abstract] [Full Text] [Related]

  • 11. Polymorphism of the epidermal growth factor receptor extracellular ligand binding domain: the dimer interface depends on domain stabilization.
    Zhang Z, Wriggers W.
    Biochemistry; 2011 Mar 29; 50(12):2144-56. PubMed ID: 21275429
    [Abstract] [Full Text] [Related]

  • 12. A variant epidermal growth factor receptor exhibits altered type alpha transforming growth factor binding and transmembrane signaling.
    Moriai T, Kobrin MS, Hope C, Speck L, Korc M.
    Proc Natl Acad Sci U S A; 1994 Oct 11; 91(21):10217-21. PubMed ID: 7937865
    [Abstract] [Full Text] [Related]

  • 13. Characterization of the N-oligosaccharides attached to the atypical Asn-X-Cys sequence of recombinant human epidermal growth factor receptor.
    Sato C, Kim JH, Abe Y, Saito K, Yokoyama S, Kohda D.
    J Biochem; 2000 Jan 11; 127(1):65-72. PubMed ID: 10731668
    [Abstract] [Full Text] [Related]

  • 14. Mechanism of epidermal growth factor receptor autophosphorylation and high-affinity binding.
    Böni-Schnetzler M, Pilch PF.
    Proc Natl Acad Sci U S A; 1987 Nov 11; 84(22):7832-6. PubMed ID: 3500470
    [Abstract] [Full Text] [Related]

  • 15. Identification of a determinant of epidermal growth factor receptor ligand-binding specificity using a truncated, high-affinity form of the ectodomain.
    Elleman TC, Domagala T, McKern NM, Nerrie M, Lönnqvist B, Adams TE, Lewis J, Lovrecz GO, Hoyne PA, Richards KM, Howlett GJ, Rothacker J, Jorissen RN, Lou M, Garrett TP, Burgess AW, Nice EC, Ward CW.
    Biochemistry; 2001 Jul 31; 40(30):8930-9. PubMed ID: 11467954
    [Abstract] [Full Text] [Related]

  • 16. Quantitation of the effect of ErbB2 on epidermal growth factor receptor binding and dimerization.
    Li Y, Macdonald-Obermann J, Westfall C, Piwnica-Worms D, Pike LJ.
    J Biol Chem; 2012 Sep 07; 287(37):31116-25. PubMed ID: 22822073
    [Abstract] [Full Text] [Related]

  • 17. Surfactant protein D suppresses lung cancer progression by downregulation of epidermal growth factor signaling.
    Hasegawa Y, Takahashi M, Ariki S, Asakawa D, Tajiri M, Wada Y, Yamaguchi Y, Nishitani C, Takamiya R, Saito A, Uehara Y, Hashimoto J, Kurimura Y, Takahashi H, Kuroki Y.
    Oncogene; 2015 Feb 12; 34(7):838-45. PubMed ID: 24608429
    [Abstract] [Full Text] [Related]

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  • 19. Different epidermal growth factor (EGF) receptor ligands show distinct kinetics and biased or partial agonism for homodimer and heterodimer formation.
    Macdonald-Obermann JL, Pike LJ.
    J Biol Chem; 2014 Sep 19; 289(38):26178-26188. PubMed ID: 25086039
    [Abstract] [Full Text] [Related]

  • 20. Gefitinib induces epidermal growth factor receptor dimers which alters the interaction characteristics with ¹²⁵I-EGF.
    Björkelund H, Gedda L, Barta P, Malmqvist M, Andersson K.
    PLoS One; 2011 Sep 19; 6(9):e24739. PubMed ID: 21931838
    [Abstract] [Full Text] [Related]

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