These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Differential alterations of dihydrofolate reductase gene in human leukemia cell lines made resistant to various folate analogues. Miyachi H, Takemura Y, Kobayashi H, Ando K, Ando Y. Jpn J Cancer Res; 1993 Jan; 84(1):9-12. PubMed ID: 8449831 [Abstract] [Full Text] [Related]
3. Expression of variant dihydrofolate reductase with decreased binding affinity to antifolates in MOLT-3 human leukemia cell lines resistant to trimetrexate. Miyachi H, Takemura Y, Kobayashi H, Ando Y. Cancer Lett; 1995 Jan 06; 88(1):93-9. PubMed ID: 7850779 [Abstract] [Full Text] [Related]
4. Dihydrofolate reductase gene expression characterized by the PCR assay in human leukemia cells. Miyachi H, Han H, Scanlon KJ. In Vivo; 1991 Jan 06; 5(1):7-12. PubMed ID: 1932630 [Abstract] [Full Text] [Related]
6. Sequence analysis of a human gene responsible for drug resistance: a rapid method for manual and automated direct sequencing of products generated by the polymerase chain reaction. Dicker AP, Volkenandt M, Adamo A, Barreda C, Bertino JR. Biotechniques; 1989 Sep 06; 7(8):830-8. PubMed ID: 2698661 [Abstract] [Full Text] [Related]
7. Plasmodium falciparum: gene mutations and amplification of dihydrofolate reductase genes in parasites grown in vitro in presence of pyrimethamine. Thaithong S, Ranford-Cartwright LC, Siripoon N, Harnyuttanakorn P, Kanchanakhan NS, Seugorn A, Rungsihirunrat K, Cravo PV, Beale GH. Exp Parasitol; 2001 Jun 06; 98(2):59-70. PubMed ID: 11465989 [Abstract] [Full Text] [Related]
8. Mutations leading to antifolate resistance in Chinese hamster ovary cells after exposure to the alkylating agent ethylmethanesulfonate. Fanin R, Banerjee D, Volkenandt M, Waltham M, Li WW, Dicker AP, Schweitzer BI, Bertino JR. Mol Pharmacol; 1993 Jul 06; 44(1):13-21. PubMed ID: 8341268 [Abstract] [Full Text] [Related]
9. Molecular mechanisms of resistance to antifolates, a review. Banerjee D, Ercikan-Abali E, Waltham M, Schnieders B, Hochhauser D, Li WW, Fan J, Gorlick R, Goker E, Bertino JR. Acta Biochim Pol; 1995 Jul 06; 42(4):457-64. PubMed ID: 8852336 [Abstract] [Full Text] [Related]
10. Generation of dual resistance to 4-hydroperoxycyclophosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class 1 gene and a mutated dihydrofolate reductase gene. Takebe N, Zhao SC, Adhikari D, Mineishi S, Sadelain M, Hilton J, Colvin M, Banerjee D, Bertino JR. Mol Ther; 2001 Jan 06; 3(1):88-96. PubMed ID: 11162315 [Abstract] [Full Text] [Related]
11. [Study on the genetic alterations in MTX-resistant cells by differential polymerase chain reaction]. Zhang Y, Deng XY, Zhang XL, Zhang GY, Li P, Fu SB. Yi Chuan Xue Bao; 2003 Apr 06; 30(4):321-4. PubMed ID: 12812055 [Abstract] [Full Text] [Related]
13. Molecular and karyological analysis of methotrexate-resistant and -sensitive human leukemic CCRF-CEM cells. Mini E, Srimatkandada S, Medina WD, Moroson BA, Carman MD, Bertino JR. Cancer Res; 1985 Jan 06; 45(1):317-24. PubMed ID: 3855283 [Abstract] [Full Text] [Related]
16. [Mice transduced with double-mutant dihydrofolate reductase-cytidine deaminase fusion gene attained protection from high dose chemotherapy]. Lu P, Lu Y, Pang K, Wang SB, Chen JQ, Xu HM, Wang JK, Zhao SC. Zhonghua Wai Ke Za Zhi; 2005 Aug 01; 43(15):998-1001. PubMed ID: 16194358 [Abstract] [Full Text] [Related]
17. Associations of antifolate resistance in vitro and point mutations in dihydrofolate reductase and dihydropteroate synthetase genes of Plasmodium falciparum. Biswas S. J Postgrad Med; 2004 Aug 01; 50(1):17-20. PubMed ID: 15047993 [Abstract] [Full Text] [Related]
18. Use of a semi-nested PCR diagnosis test to evaluate antifolate resistance of Plasmodium falciparum isolates. Eldin de Pecoulas P, Abdallah B, Dje MK, Basco LK, le Bras J, Mazabraud A. Mol Cell Probes; 1995 Dec 01; 9(6):391-7. PubMed ID: 8808309 [Abstract] [Full Text] [Related]