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Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

159 related items for PubMed ID: 8374044

  • 1. Mechanism-based inactivation of cytochrome P450 2B1 by 2-ethynylnaphthalene: identification of an active-site peptide.
    Roberts ES, Hopkins NE, Alworth WL, Hollenberg PF.
    Chem Res Toxicol; 1993; 6(4):470-9. PubMed ID: 8374044
    [Abstract] [Full Text] [Related]

  • 2. Identification of active-site peptides from 3H-labeled 2-ethynylnaphthalene-inactivated P450 2B1 and 2B4 using amino acid sequencing and mass spectrometry.
    Roberts ES, Hopkins NE, Zaluzec EJ, Gage DA, Alworth WL, Hollenberg PF.
    Biochemistry; 1994 Mar 29; 33(12):3766-71. PubMed ID: 8142377
    [Abstract] [Full Text] [Related]

  • 3. Mechanism-based inactivation of cytochrome P450 2B1 by 9-ethynylphenanthrene.
    Roberts ES, Hopkins NE, Zaluzec EJ, Gage DA, Alworth WL, Hollenberg PF.
    Arch Biochem Biophys; 1995 Nov 10; 323(2):295-302. PubMed ID: 7487091
    [Abstract] [Full Text] [Related]

  • 4. Inactivation of cytochrome P450 2B1 by benzyl isothiocyanate, a chemopreventative agent from cruciferous vegetables.
    Goosen TC, Kent UM, Brand L, Hollenberg PF.
    Chem Res Toxicol; 2000 Dec 10; 13(12):1349-59. PubMed ID: 11123978
    [Abstract] [Full Text] [Related]

  • 5. Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by 2-phenyl-2-(1-piperidinyl)propane.
    Chun J, Kent UM, Moss RM, Sayre LM, Hollenberg PF.
    Drug Metab Dispos; 2000 Aug 10; 28(8):905-11. PubMed ID: 10901699
    [Abstract] [Full Text] [Related]

  • 6. Identification of the heme adduct and an active site peptide modified during mechanism-based inactivation of rat liver cytochrome P450 2B1 by secobarbital.
    He K, Falick AM, Chen B, Nilsson F, Correia MA.
    Chem Res Toxicol; 1996 Aug 10; 9(3):614-22. PubMed ID: 8728507
    [Abstract] [Full Text] [Related]

  • 7. Inactivation of cytochrome P450s 2B1, 2B4, 2B6, and 2B11 by arylalkynes.
    Roberts ES, Hopkins NE, Foroozesh M, Alworth WL, Halpert JR, Hollenberg PF.
    Drug Metab Dispos; 1997 Nov 10; 25(11):1242-8. PubMed ID: 9351899
    [Abstract] [Full Text] [Related]

  • 8. Effect of 17-alpha-ethynylestradiol on activities of cytochrome P450 2B (P450 2B) enzymes: characterization of inactivation of P450s 2B1 and 2B6 and identification of metabolites.
    Kent UM, Mills DE, Rajnarayanan RV, Alworth WL, Hollenberg PF.
    J Pharmacol Exp Ther; 2002 Feb 10; 300(2):549-58. PubMed ID: 11805216
    [Abstract] [Full Text] [Related]

  • 9. Mechanistic studies of 9-ethynylphenanthrene-inactivated cytochrome P450 2B1.
    Roberts ES, Ballou DP, Hopkins NE, Alworth WL, Hollenberg PF.
    Arch Biochem Biophys; 1995 Nov 10; 323(2):303-12. PubMed ID: 7487092
    [Abstract] [Full Text] [Related]

  • 10. A role for threonine 302 in the mechanism-based inactivation of P450 2B4 by 2-ethynylnaphthalene.
    Roberts ES, Pernecky SJ, Alworth WL, Hollenberg PF.
    Arch Biochem Biophys; 1996 Jul 15; 331(2):170-6. PubMed ID: 8660695
    [Abstract] [Full Text] [Related]

  • 11. Peroxynitrite-mediated nitration of tyrosine and inactivation of the catalytic activity of cytochrome P450 2B1.
    Roberts ES, Lin Hl, Crowley JR, Vuletich JL, Osawa Y, Hollenberg PF.
    Chem Res Toxicol; 1998 Sep 15; 11(9):1067-74. PubMed ID: 9760281
    [Abstract] [Full Text] [Related]

  • 12. The functional role of threonine-205 in the mechanism-based inactivation of P450 2B1 by two ethynyl substrates: the importance of the F helix in catalysis.
    Lin HL, Kent UM, Zhang H, Waskell L, Hollenberg PF.
    J Pharmacol Exp Ther; 2004 Dec 15; 311(3):855-63. PubMed ID: 15302894
    [Abstract] [Full Text] [Related]

  • 13. Modification of cytochrome P450 1A2 enzymes by the mechanism-based inactivator 2-ethynylnaphthalene and the photoaffinity label 4-azidobiphenyl.
    Yun CH, Hammons GJ, Jones G, Martin MV, Hopkins NE, Alworth WL, Guengerich FP.
    Biochemistry; 1992 Nov 03; 31(43):10556-63. PubMed ID: 1420171
    [Abstract] [Full Text] [Related]

  • 14. Aryl acetylenes as mechanism-based inhibitors of cytochrome P450-dependent monooxygenase enzymes.
    Foroozesh M, Primrose G, Guo Z, Bell LC, Alworth WL, Guengerich FP.
    Chem Res Toxicol; 1997 Jan 03; 10(1):91-102. PubMed ID: 9074808
    [Abstract] [Full Text] [Related]

  • 15. Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by n-propylxanthate.
    Kent UM, Yanev S, Hollenberg PF.
    Chem Res Toxicol; 1999 Apr 03; 12(4):317-22. PubMed ID: 10207119
    [Abstract] [Full Text] [Related]

  • 16. Mechanism-based inactivation of cytochrome P-450-3A4 by mifepristone (RU486).
    He K, Woolf TF, Hollenberg PF.
    J Pharmacol Exp Ther; 1999 Feb 03; 288(2):791-7. PubMed ID: 9918590
    [Abstract] [Full Text] [Related]

  • 17. Suicide inhibitors of cytochrome P450 1A1 and P450 2B1.
    Hopkins NE, Foroozesh MK, Alworth WL.
    Biochem Pharmacol; 1992 Aug 18; 44(4):787-96. PubMed ID: 1510726
    [Abstract] [Full Text] [Related]

  • 18. Cumene hydroperoxide-mediated inactivation of cytochrome P450 2B1. Identification of an active site heme-modified peptide.
    Yao K, Falick AM, Patel N, Correia MA.
    J Biol Chem; 1993 Jan 05; 268(1):59-65. PubMed ID: 8416964
    [Abstract] [Full Text] [Related]

  • 19. Mechanism-based inactivation of cytochrome P450 2B1 by N-benzyl-1-aminobenzotriazole.
    Kent UM, Bend JR, Chamberlin BA, Gage DA, Hollenberg PF.
    Chem Res Toxicol; 1997 May 05; 10(5):600-8. PubMed ID: 9168259
    [Abstract] [Full Text] [Related]

  • 20. Mechanism-based inactivation of cytochrome P450 3A4 by 17 alpha-ethynylestradiol: evidence for heme destruction and covalent binding to protein.
    Lin HL, Kent UM, Hollenberg PF.
    J Pharmacol Exp Ther; 2002 Apr 05; 301(1):160-7. PubMed ID: 11907170
    [Abstract] [Full Text] [Related]

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