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Journal Abstract Search

161 related items for PubMed ID: 8381634

  • 1. Generation of drug-resistant variants of human immunodeficiency virus type 1 by in vitro passage in increasing concentrations of 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine.
    Gao Q, Gu Z, Hiscott J, Dionne G, Wainberg MA.
    Antimicrob Agents Chemother; 1993 Jan; 37(1):130-3. PubMed ID: 8381634
    [Abstract] [Full Text] [Related]

  • 2. Infectious amplification of wild-type human immunodeficiency virus from patients' lymphocytes and modulation by reverse transcriptase inhibitors in vitro.
    Mathez D, Schinazi RF, Liotta DC, Leibowitch J.
    Antimicrob Agents Chemother; 1993 Oct; 37(10):2206-11. PubMed ID: 7504908
    [Abstract] [Full Text] [Related]

  • 3. Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase.
    Tisdale M, Kemp SD, Parry NR, Larder BA.
    Proc Natl Acad Sci U S A; 1993 Jun 15; 90(12):5653-6. PubMed ID: 7685907
    [Abstract] [Full Text] [Related]

  • 4. Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides.
    Schinazi RF, Lloyd RM, Nguyen MH, Cannon DL, McMillan A, Ilksoy N, Chu CK, Liotta DC, Bazmi HZ, Mellors JW.
    Antimicrob Agents Chemother; 1993 Apr 15; 37(4):875-81. PubMed ID: 7684216
    [Abstract] [Full Text] [Related]

  • 5. The same mutation that encodes low-level human immunodeficiency virus type 1 resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine confers high-level resistance to the (-) enantiomer of 2',3'-dideoxy-3'-thiacytidine.
    Gao Q, Gu Z, Parniak MA, Cameron J, Cammack N, Boucher C, Wainberg MA.
    Antimicrob Agents Chemother; 1993 Jun 15; 37(6):1390-2. PubMed ID: 8392313
    [Abstract] [Full Text] [Related]

  • 6. Changes in drug sensitivity of human immunodeficiency virus type 1 during therapy with azidothymidine, dideoxycytidine, and dideoxyinosine: an in vitro comparative study.
    Shirasaka T, Yarchoan R, O'Brien MC, Husson RN, Anderson BD, Kojima E, Shimada T, Broder S, Mitsuya H.
    Proc Natl Acad Sci U S A; 1993 Jan 15; 90(2):562-6. PubMed ID: 8380641
    [Abstract] [Full Text] [Related]

  • 7. Anti-human immunodeficiency virus activities of the beta-L enantiomer of 2',3'-dideoxycytidine and its 5-fluoro derivative in vitro.
    Gosselin G, Schinazi RF, Sommadossi JP, Mathé C, Bergogne MC, Aubertin AM, Kirn A, Imbach JL.
    Antimicrob Agents Chemother; 1994 Jun 15; 38(6):1292-7. PubMed ID: 8092827
    [Abstract] [Full Text] [Related]

  • 8. Phosphatidyl-2',3'-dideoxy-3'-thiacytidine: synthesis and antiviral activity in hepatitis B-and HIV-1-infected cells.
    Xie H, Voronkov M, Liotta DC, Korba BA, Schinazi RF, Richman DD, Hostetler KY.
    Antiviral Res; 1995 Oct 15; 28(2):113-20. PubMed ID: 8585765
    [Abstract] [Full Text] [Related]

  • 9. Generation of multiple drug resistance by sequential in vitro passage of the human immunodeficiency virus type 1.
    Gao Q, Gu Z, Salomon H, Nagai K, Parniak MA, Wainberg MA.
    Arch Virol; 1994 Oct 15; 136(1-2):111-22. PubMed ID: 8002779
    [Abstract] [Full Text] [Related]

  • 10. The K65R mutant reverse transcriptase of HIV-1 cross-resistant to 2', 3'-dideoxycytidine, 2',3'-dideoxy-3'-thiacytidine, and 2',3'-dideoxyinosine shows reduced sensitivity to specific dideoxynucleoside triphosphate inhibitors in vitro.
    Gu Z, Fletcher RS, Arts EJ, Wainberg MA, Parniak MA.
    J Biol Chem; 1994 Nov 11; 269(45):28118-22. PubMed ID: 7525567
    [Abstract] [Full Text] [Related]

  • 11. Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes.
    Schinazi RF, Chu CK, Peck A, McMillan A, Mathis R, Cannon D, Jeong LS, Beach JW, Choi WB, Yeola S.
    Antimicrob Agents Chemother; 1992 Mar 11; 36(3):672-6. PubMed ID: 1320365
    [Abstract] [Full Text] [Related]

  • 12. Biological comparison of wild-type and zidovudine-resistant isolates of human immunodeficiency virus type 1 from the same subjects: susceptibility and resistance to other drugs.
    Rooke R, Parniak MA, Tremblay M, Soudeyns H, Li XG, Gao Q, Yao XJ, Wainberg MA.
    Antimicrob Agents Chemother; 1991 May 11; 35(5):988-91. PubMed ID: 1649576
    [Abstract] [Full Text] [Related]

  • 13. High-level resistance to (-) enantiomeric 2'-deoxy-3'-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase.
    Boucher CA, Cammack N, Schipper P, Schuurman R, Rouse P, Wainberg MA, Cameron JM.
    Antimicrob Agents Chemother; 1993 Oct 11; 37(10):2231-4. PubMed ID: 7504909
    [Abstract] [Full Text] [Related]

  • 14. Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine.
    Gu Z, Gao Q, Fang H, Salomon H, Parniak MA, Goldberg E, Cameron J, Wainberg MA.
    Antimicrob Agents Chemother; 1994 Feb 11; 38(2):275-81. PubMed ID: 7514855
    [Abstract] [Full Text] [Related]

  • 15. Bisheteroarylpiperazine reverse transcriptase inhibitor in combination with 3'-azido-3'-deoxythymidine or 2',3'-dideoxycytidine synergistically inhibits human immunodeficiency virus type 1 replication in vitro.
    Chong KT, Pagano PJ, Hinshaw RR.
    Antimicrob Agents Chemother; 1994 Feb 11; 38(2):288-93. PubMed ID: 7514857
    [Abstract] [Full Text] [Related]

  • 16. Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine.
    Gu Z, Gao Q, Li X, Parniak MA, Wainberg MA.
    J Virol; 1992 Dec 11; 66(12):7128-35. PubMed ID: 1279198
    [Abstract] [Full Text] [Related]

  • 17. Multiple-drug-resistant mutants of feline immunodeficiency virus selected with 2',3'-dideoxyinosine alone and in combination with 3'-azido-3'-deoxythymidine.
    Gobert JM, Remington KM, Zhu YQ, North TW.
    Antimicrob Agents Chemother; 1994 Apr 11; 38(4):861-4. PubMed ID: 8031060
    [Abstract] [Full Text] [Related]

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  • 19. Synthesis and anti-HIV-1 activity of 2'-"up"-fluoro analogues of active anti-AIDS nucleosides 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (DDC).
    Watanabe KA, Harada K, Zeidler J, Matulic-Adamic J, Takahashi K, Ren WY, Cheng LC, Fox JJ, Chou TC, Zhu QY.
    J Med Chem; 1990 Aug 11; 33(8):2145-50. PubMed ID: 1695683
    [Abstract] [Full Text] [Related]

  • 20. Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine.
    Schinazi RF, McMillan A, Cannon D, Mathis R, Lloyd RM, Peck A, Sommadossi JP, St Clair M, Wilson J, Furman PA.
    Antimicrob Agents Chemother; 1992 Nov 11; 36(11):2423-31. PubMed ID: 1283296
    [Abstract] [Full Text] [Related]

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