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Journal Abstract Search

555 related items for PubMed ID: 8386278

  • 1. Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites.
    Grakoui A, McCourt DW, Wychowski C, Feinstone SM, Rice CM.
    J Virol; 1993 May; 67(5):2832-43. PubMed ID: 8386278
    [Abstract] [Full Text] [Related]

  • 2. Hepatitis C virus NS3 serine proteinase: trans-cleavage requirements and processing kinetics.
    Lin C, Prágai BM, Grakoui A, Xu J, Rice CM.
    J Virol; 1994 Dec; 68(12):8147-57. PubMed ID: 7966606
    [Abstract] [Full Text] [Related]

  • 3. Specificity of the hepatitis C virus NS3 serine protease: effects of substitutions at the 3/4A, 4A/4B, 4B/5A, and 5A/5B cleavage sites on polyprotein processing.
    Kolykhalov AA, Agapov EV, Rice CM.
    J Virol; 1994 Nov; 68(11):7525-33. PubMed ID: 7933136
    [Abstract] [Full Text] [Related]

  • 4. Substrate determinants for cleavage in cis and in trans by the hepatitis C virus NS3 proteinase.
    Bartenschlager R, Ahlborn-Laake L, Yasargil K, Mous J, Jacobsen H.
    J Virol; 1995 Jan; 69(1):198-205. PubMed ID: 7983710
    [Abstract] [Full Text] [Related]

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  • 6. Complex formation between the NS3 serine-type proteinase of the hepatitis C virus and NS4A and its importance for polyprotein maturation.
    Bartenschlager R, Lohmann V, Wilkinson T, Koch JO.
    J Virol; 1995 Dec; 69(12):7519-28. PubMed ID: 7494258
    [Abstract] [Full Text] [Related]

  • 7. Substrate specificity of the NS3 serine proteinase of hepatitis C virus as determined by mutagenesis at the NS3/NS4A junction.
    Leinbach SS, Bhat RA, Xia SM, Hum WT, Stauffer B, Davis AR, Hung PP, Mizutani S.
    Virology; 1994 Oct; 204(1):163-9. PubMed ID: 8091650
    [Abstract] [Full Text] [Related]

  • 8. Bovine viral diarrhea virus NS3 serine proteinase: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replication.
    Xu J, Mendez E, Caron PR, Lin C, Murcko MA, Collett MS, Rice CM.
    J Virol; 1997 Jul; 71(7):5312-22. PubMed ID: 9188600
    [Abstract] [Full Text] [Related]

  • 9. The hepatitis C virus NS3 serine proteinase and NS4A cofactor: establishment of a cell-free trans-processing assay.
    Lin C, Rice CM.
    Proc Natl Acad Sci U S A; 1995 Aug 15; 92(17):7622-6. PubMed ID: 7644466
    [Abstract] [Full Text] [Related]

  • 10. Mutagenesis of conserved residues at the yellow fever virus 3/4A and 4B/5 dibasic cleavage sites: effects on cleavage efficiency and polyprotein processing.
    Lin C, Chambers TJ, Rice CM.
    Virology; 1993 Feb 15; 192(2):596-604. PubMed ID: 8421901
    [Abstract] [Full Text] [Related]

  • 11. An in vitro assay for hepatitis C virus NS3 serine proteinase.
    Bouffard P, Bartenschlager R, Ahlborn-Laake L, Mous J, Roberts N, Jacobsen H.
    Virology; 1995 May 10; 209(1):52-9. PubMed ID: 7747484
    [Abstract] [Full Text] [Related]

  • 12. Cleavage at a novel site in the NS4A region by the yellow fever virus NS2B-3 proteinase is a prerequisite for processing at the downstream 4A/4B signalase site.
    Lin C, Amberg SM, Chambers TJ, Rice CM.
    J Virol; 1993 Apr 10; 67(4):2327-35. PubMed ID: 8445732
    [Abstract] [Full Text] [Related]

  • 13. Proteolytic processing of a Murray Valley encephalitis virus non-structural polyprotein segment containing the viral proteinase: accumulation of a NS3-4A precursor which requires mature NS3 for efficient processing.
    Lobigs M.
    J Gen Virol; 1992 Sep 10; 73 ( Pt 9)():2305-12. PubMed ID: 1328486
    [Abstract] [Full Text] [Related]

  • 14. Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins.
    Failla C, Tomei L, De Francesco R.
    J Virol; 1994 Jun 10; 68(6):3753-60. PubMed ID: 8189513
    [Abstract] [Full Text] [Related]

  • 15. The hepatitis C virus NS4A protein: interactions with the NS4B and NS5A proteins.
    Lin C, Wu JW, Hsiao K, Su MS.
    J Virol; 1997 Sep 10; 71(9):6465-71. PubMed ID: 9261364
    [Abstract] [Full Text] [Related]

  • 16. The hepatitis C virus NS3 proteinase: structure and function of a zinc-containing serine proteinase.
    De Francesco R, Pessi A, Steinkühler C.
    Antivir Ther; 1998 Sep 10; 3(Suppl 3):99-109. PubMed ID: 10726060
    [Abstract] [Full Text] [Related]

  • 17. Virus-specific cofactor requirement and chimeric hepatitis C virus/GB virus B nonstructural protein 3.
    Butkiewicz N, Yao N, Zhong W, Wright-Minogue J, Ingravallo P, Zhang R, Durkin J, Standring DN, Baroudy BM, Sangar DV, Lemon SM, Lau JY, Hong Z.
    J Virol; 2000 May 10; 74(9):4291-301. PubMed ID: 10756044
    [Abstract] [Full Text] [Related]

  • 18. The design and synthesis of potent inhibitors of hepatitis C virus NS3-4A proteinase.
    Attwood MR, Bennett JM, Campbell AD, Canning GG, Carr MG, Conway E, Dunsdon RM, Greening JR, Jones PS, Kay PB, Handa BK, Hurst DN, Jennings NS, Jordan S, Keech E, O'Brien MA, Overton HA, King-Underwood J, Raynham TM, Stenson KP, Wilkinson CS, Wilkinson TC, Wilson FX.
    Antivir Chem Chemother; 1999 Sep 10; 10(5):259-73. PubMed ID: 10574181
    [Abstract] [Full Text] [Related]

  • 19. Enhancement of hepatitis C virus NS3 proteinase activity by association with NS4A-specific synthetic peptides: identification of sequence and critical residues of NS4A for the cofactor activity.
    Butkiewicz NJ, Wendel M, Zhang R, Jubin R, Pichardo J, Smith EB, Hart AM, Ingram R, Durkin J, Mui PW, Murray MG, Ramanathan L, Dasmahapatra B.
    Virology; 1996 Nov 15; 225(2):328-38. PubMed ID: 8918919
    [Abstract] [Full Text] [Related]

  • 20. Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions.
    Bartenschlager R, Ahlborn-Laake L, Mous J, Jacobsen H.
    J Virol; 1993 Jul 15; 67(7):3835-44. PubMed ID: 8389908
    [Abstract] [Full Text] [Related]

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