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Journal Abstract Search

174 related items for PubMed ID: 8390680

  • 1. Optimizing transmembrane domain helicity accelerates insulin receptor internalization and lateral mobility.
    Goncalves E, Yamada K, Thatte HS, Backer JM, Golan DE, Kahn CR, Shoelson SE.
    Proc Natl Acad Sci U S A; 1993 Jun 15; 90(12):5762-6. PubMed ID: 8390680
    [Abstract] [Full Text] [Related]

  • 2. An irregularity in the transmembrane domain helix correlates with the rate of insulin receptor internalization.
    Li SC, Deber CM, Shoelson SE.
    Biochemistry; 1994 Nov 29; 33(47):14333-8. PubMed ID: 7947843
    [Abstract] [Full Text] [Related]

  • 3. Role of the transmembrane domain and flanking amino acids in internalization and down-regulation of the insulin receptor.
    Yamada K, Carpentier JL, Cheatham B, Goncalves E, Shoelson SE, Kahn CR.
    J Biol Chem; 1995 Feb 17; 270(7):3115-22. PubMed ID: 7852393
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  • 4. Substitution of the insulin receptor transmembrane domain with the c-neu/erbB2 transmembrane domain constitutively activates the insulin receptor kinase in vitro.
    Yamada K, Goncalves E, Kahn CR, Shoelson SE.
    J Biol Chem; 1992 Jun 25; 267(18):12452-61. PubMed ID: 1352286
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  • 6. Deletion of C-terminal 113 amino acids impairs processing and internalization of human insulin receptor: comparison of receptors expressed in CHO and NIH-3T3 cells.
    Levy-Toledano R, Accili D, Taylor SI.
    Biochim Biophys Acta; 1993 Dec 16; 1220(1):1-14. PubMed ID: 8268238
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  • 8. Two sequences flanking the major autophosphorylation site of the insulin receptor are essential for tyrosine kinase activation.
    Leconte I, Clauser E.
    Biochem J; 1995 Mar 01; 306 ( Pt 2)(Pt 2):465-72. PubMed ID: 7887900
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  • 10. Insulin internalization in the absence of the insulin receptor tyrosine kinase domain is insufficient for mediating intracellular biological effects.
    Schranz DB, Rohilla AM, Anderson C, Wood WM, Berhanu P.
    Biochem Biophys Res Commun; 1996 Oct 14; 227(2):600-7. PubMed ID: 8878559
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  • 11. Activation of insulin receptor signaling by a single amino acid substitution in the transmembrane domain.
    Longo N, Shuster RC, Griffin LD, Langley SD, Elsas LJ.
    J Biol Chem; 1992 Jun 25; 267(18):12416-9. PubMed ID: 1618747
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  • 12. Substitution of the insulin receptor transmembrane domain with that of glycophorin A inhibits insulin action.
    Gardin A, Auzan C, Clauser E, Malherbe T, Aunis D, Crémel G, Hubert P.
    FASEB J; 1999 Aug 25; 13(11):1347-57. PubMed ID: 10428759
    [Abstract] [Full Text] [Related]

  • 13. Insulin receptors internalize by a rapid, saturable pathway requiring receptor autophosphorylation and an intact juxtamembrane region.
    Backer JM, Shoelson SE, Haring E, White MF.
    J Cell Biol; 1991 Dec 25; 115(6):1535-45. PubMed ID: 1757462
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  • 14. The insulin receptor juxtamembrane region contains two independent tyrosine/beta-turn internalization signals.
    Backer JM, Shoelson SE, Weiss MA, Hua QX, Cheatham RB, Haring E, Cahill DC, White MF.
    J Cell Biol; 1992 Aug 25; 118(4):831-9. PubMed ID: 1500426
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  • 15. The level of insulin receptor tyrosine kinase activity modulates the activities of phosphatidylinositol 3-kinase, microtubule-associated protein, and S6 kinases.
    Wilden PA, Kahn CR.
    Mol Endocrinol; 1994 May 25; 8(5):558-67. PubMed ID: 8058065
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  • 16. The role of insulin receptor kinase domain autophosphorylation in receptor-mediated activities. Analysis with insulin and anti-receptor antibodies.
    Wilden PA, Siddle K, Haring E, Backer JM, White MF, Kahn CR.
    J Biol Chem; 1992 Jul 05; 267(19):13719-27. PubMed ID: 1320027
    [Abstract] [Full Text] [Related]

  • 17. Asn229 in the third helix of VPAC1 receptor is essential for receptor activation but not for receptor phosphorylation and internalization: comparison with Asn216 in VPAC2 receptor.
    Nachtergael I, Gaspard N, Langlet C, Robberecht P, Langer I.
    Cell Signal; 2006 Dec 05; 18(12):2121-30. PubMed ID: 16650965
    [Abstract] [Full Text] [Related]

  • 18. Insulin receptor transmembrane signaling: evidence for an intermolecular oligomerization mechanism of activation.
    Mynarcik DC, Whittaker J.
    J Recept Signal Transduct Res; 1995 Dec 05; 15(7-8):887-904. PubMed ID: 8673722
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  • 19. A domain of the insulin receptor required for endocytosis in rat fibroblasts.
    Thies RS, Webster NJ, McClain DA.
    J Biol Chem; 1990 Jun 15; 265(17):10132-7. PubMed ID: 2161833
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  • 20. Cysteine-524 is not the only residue involved in the formation of disulphide-bonded dimers of the insulin receptor.
    Macaulay SL, Polites M, Hewish DR, Ward CW.
    Biochem J; 1994 Oct 15; 303 ( Pt 2)(Pt 2):575-81. PubMed ID: 7980420
    [Abstract] [Full Text] [Related]

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